Izinto eziluncedo kwiBanga le-Pharmaceutical HPMC

HPMC iye yaba yenye excipients amayeza asetyenziswa kakhulu ekhaya nakwamanye amazwe, kuba HPMC iingenelo ukuba ezinye excipients abanazo.

1. Ukunyibilika kwamanzi

Inyibilika kumanzi abandayo angaphantsi kwe-40 ° C okanye i-70% ye-ethanol, ngokusisiseko ayinyibiliki emanzini ashushu ngaphezu kwe-60 ° C, kodwa i-gel.

2. Ukungangeni kweMichiza

HPMC luhlobo non-ionici-cellulose ether. Isisombululo sayo asinayo i-ionic kwaye ayisebenzisi kunye neetyuwa zetsimbi okanye i-ionic organic compounds. Ngoko ke, abanye abancedisi abaphenduli kunye nayo ngexesha lenkqubo yokulungiselela.

3. Ukuzinza

Izinzile kwi-asidi kunye ne-alkali, kwaye inokugcinwa ixesha elide phakathi kwe-pH 3 kunye ne-11 ngaphandle kotshintsho olucacileyo kwi-viscosity. Isisombululo samanzi se-HPMC sinomphumela wokulwa nokubola kwaye sinokugcina uzinzo oluhle lwe-viscosity ngexesha lokugcinwa kwexesha elide. Uzinzo lomgangatho wamayeza asebenzisa i-HPMC njengabancedisi bamalungiselelo lungcono kunolo lwamayeza asebenzisa izincedisi zesintu (ezifana ne-dextrin, istatshi, njl. njl.).

4. I-viscosity ehlengahlengiswayo

I-viscosity derivatives eyahlukeneyo ye-HPMC inokuxutywa ngokwemilinganiselo eyahlukeneyo, kwaye i-viscosity yayo inokutshintsha ngokwemigaqo ethile, kwaye inobudlelwane obuhle bomgca, ngoko umlinganiselo unokukhethwa ngokweemfuno. 2.5 I-Metabolism inert ye-HPMC ayixutywanga okanye i-metabolized emzimbeni, kwaye ayinikezeli ubushushu, ngoko ke i-excipient ekhuselekileyo yokulungiselela amayeza. .

5. Ukhuseleko

I-HPMC ithathwa njengezinto ezingeyotyhefu nezingacaphukisiyo.