1. Litšobotsi tse sa tšoaneng
Hydroxypropyl methylcellulose: phofo e tšoeu kapa e sa bosoeu e nang le fibrous kapa granular, e leng ea mefuta e fapaneng ea li-ether tse sa tšoaneng tsa cellulose tse tsoakiloeng. Ke polymer ea semi-synthetic, e sa sebetseng, e nang le viscoelastic.
Hydroxyethyl cellulose: (HEC) ke bosehla bo bosoeu kapa bo bobebe, bo se nang monko, bo se nang chefo kapa bo tiileng ba phofshoana, bo lokiselitsoeng ka etherification ea alkaline cellulose le ethylene oxide (kapa chloroethanol). Ke ea li-non-ionic soluble cellulose ethers.
2. Litšebeliso tse fapaneng
Hydroxypropyl methylcellulose: E sebelisoa e le motenya, dispersant le stabilizer indastering ea ho roala, 'me e na le tumellano e ntle ea metsi kapa lihlahisoa tsa tlhaho. E le ho tlosa pente; e le dispersant tlhahiso ea polyvinyl chloride, ke moemeli ea ka sehloohong ea thusang bakeng sa ho lokisoa ha PVC ka ho emisa polymerization; e boetse e sebelisoa haholo indastering ea letlalo, lihlahisoa tsa pampiri, ho boloka litholoana le meroho le indastering ea masela.
Hydroxyethyl cellulose: e sebelisoa e le sekhomaretsi, surfactant, colloidal protective agent, dispersant, emulsifier le dispersion stabilizer, joalo-joalo E na le mefuta e mengata ea likopo tsa ho roala, li-inki, likhoele, ho daea, ho etsa pampiri, litlolo, chefo e bolaeang likokoanyana, ts'ebetso ea liminerale, ho ntšoa ha oli. le meriana.
3. Fapaneng solubility
Hydroxypropyl methylcellulose: E batla e sa qhibilihe ka ho feletseng ka ethanol, ether, le acetone; e ruruhile ho ba motsoako o hlakileng kapa o fokolang oa colloidal ka metsing a batang.
Hydroxyethyl cellulose: e na le thepa ea ho tiisa, ho emisa, ho kopanya, ho etsa emulsifying, ho hasanya le ho boloka mongobo. Litharollo tse nang le mefuta e fapaneng ea viscosity li ka lokisoa. E na le ho qhibiliha ha letsoai ka mokhoa o ikhethang ho li-electrolyte.
Hydroxypropyl methylcellulose (HPMC) Thepa ea 'mele le ea lik'hemik'hale:
1. Ponahalo: MC e tšoeu kapa e batla e le tšoeu ea fibrous kapa granular powder, ha e na monko.
2. Thepa: MC e batla e sa qhibilihe ka ho feletseng ka ethanol, ether le acetone. E hasana le ho ruruha ka potlako metsing a chesang a 80 ~ 90 ℃, 'me e qhibiliha kapele ka mor'a ho pholile. Tharollo ea metsi e tsitsitse haholo mocheso oa kamore 'me e ka gel ka mocheso o phahameng,' me gel e ka fetoha ka tharollo ka mocheso. E na le mongobo o motle haholo, dispersibility, adhesion, thickening, emulsification, ho boloka metsi le thepa ea ho etsa filimi, hammoho le ho se lekane ha mafura. Filimi e entsoeng e na le ho tiea ho hoholo, ho tenyetseha le ho pepeseha. Hobane ha e na ionic, e ka lumellana le li-emulsifiers tse ling, empa ho bonolo ho tsoa letsoai 'me tharollo e tsitsitse ka har'a mefuta ea PH2-12.
3. Boima bo bonahalang: 0.30-0.70g / cm3, boima bo ka bang 1.3g / cm3.
2. Mokhoa oa ho qhala:
Sehlahisoa sa MC se kenyelletsoa ka ho toba metsing, se tla kopanya ebe se qhibiliha, empa ho qhibiliha hona ho lieha haholo ebile ho thata.Mekhoa e meraro e latelang ea ho qhibiliha e hlahisoa, 'me mosebedisi a ka khetha mokhoa o loketseng ka ho fetisisa ho ea ka boemo ba tšebeliso:
1. Mokhoa oa metsi a chesang: Kaha MC ha e qhale metsing a chesang, MC e ka qhalakanngoa ka ho lekana metsing a chesang qalong. Ha e pholile ka mor'a moo, mekhoa e 'meli e tloaelehileng e hlalosoa ka tsela e latelang:
1). Kenya palo e hlokahalang ea metsi a chesang ka har'a sets'oants'o 'me ue chese ho fihlela ho 70°C. Butle-butle eketsa MC tlas'a pherekano butle, qala ho phaphamala holim'a metsi, ebe butle-butle u theha seretse, 'me u phophole seretse tlas'a pherekano.
2). Kenya 1/3 kapa 2/3 ea palo e hlokahalang ea metsi ka har'a sets'oants'o 'me ue chese ho 70 ℃. Latela mokhoa oa 1) ho qhalakanya MC ho lokisetsa slurry ea metsi a chesang; ebe o eketsa palo e setseng ea metsi a batang kapa metsi a leqhoa Ka har'a slurry ea metsi a chesang, pholisa motsoako ka mor'a ho hlohlelletsa.
2. Mokhoa oa ho kopanya phofo: Kopanya likaroloana tsa phofo tsa MC ka tekanyo e lekanang kapa e khōloanyane ea lisebelisoa tse ling tsa phofo ho li qhalakanya ka ho feletseng ka ho kopanya ho omileng, ebe o eketsa metsi ho qhibiliha, ebe MC e ka qhibiliha ntle le ho kopanya.
3. Organic solvent wetting method: pele o qhalakanya kapa moisten MC ka solvent organic, tse kang ethanol, ethylene glycol kapa oli, ebe o eketsa metsi ho qhibiliha, joale MC e ka boela ea qhibiliha hantle ka nako ena.
3. Sepheo:
Sehlahisoa sena se sebelisoa haholo kahong ea moaho, thepa ea moaho, liphahlo tse qhalakaneng, li-wallpaper, li-additives tsa polymerization, tse tlosang pente, letlalo, enke, pampiri, joalo-joalo joalo ka li-thickeners, li-adhesives, tse bolokang metsi, li-agent tse etsang filimi, Excipients, jj. . Ka mohlala, e sebelisoa e le se tlamang, se teteaneng le se bolokang metsi ka thepa ea mohaho, e le ntho e etsang filimi le e teteaneng indastering ea ho roala, hape e sebelisoa haholo masimong a kang ho cheka peterole le indasteri ea letsatsi le letsatsi ea lik'hemik'hale tsa lik'hemik'hale. .
Lintho tsa 'mele le tsa lik'hemik'hale tsa methyl cellulose (MC):
3. Ponahalo: MC e tšoeu kapa e batla e le tšoeu ea fibrous kapa granular powder, ha e na monko.
Thepa: MC e batla e sa qhibilihe ka ethanol, ether le acetone. E qhalakanngoa le ho ruruha ka potlako metsing a chesang a 80 ~ 90> ℃, 'me e qhibiliha kapele ka mor'a ho pholile. Tharollo ea metsi e tsitsitse ka mocheso o tloaelehileng 'me e ka gel ka mocheso o phahameng,' me gel e ka fetoha ka tharollo ka mocheso. E na le mongobo o motle haholo, dispersibility, adhesion, thickening, emulsification, ho boloka metsi le thepa ea ho etsa filimi, hammoho le ho se lekane ha mafura. Filimi e entsoeng e na le ho tiea ho hoholo, ho tenyetseha le ho pepeseha. Hobane ha e na ionic, e ka lumellana le li-emulsifiers tse ling, empa ho bonolo ho tsoa letsoai 'me tharollo e tsitsitse ka har'a mefuta ea PH2-12.
1. Boima bo hlakileng: 0.30-0.70g / cm3, boima bo ka bang 1.3g / cm3.
Ea pele. Mokhoa oa ho hlakola:
MC> Sehlahisoa se kenngoa ka ho toba metsing, se tla kopanya ebe se qhibiliha, empa ho qhibiliha hona ho lieha haholo ebile ho thata. Ho fanoe ka mekhoa e meraro e latelang ea ho qhala, 'me basebelisi ba ka khetha mokhoa o bonolo ka ho fetisisa ho latela maemo a ts'ebeliso:
1. Mokhoa oa metsi a chesang: Kaha MC ha e qhale metsing a chesang, MC e ka qhalakanngoa ka ho lekana metsing a chesang qalong. Ha e pholile ka mor'a moo, mekhoa e 'meli e tloaelehileng e hlalosoa ka tsela e latelang:
1). Kenya palo e hlokahalang ea metsi a chesang ka har'a sets'oants'o 'me ue chese ho fihlela ho 70°C. Butle-butle eketsa MC tlas'a pherekano butle, qala ho phaphamala holim'a metsi, ebe butle-butle u theha seretse, 'me u phophole seretse tlas'a pherekano.
2). Kenya 1/3 kapa 2/3 ea palo e hlokahalang ea metsi ka har'a sets'oants'o ebe o se futhumatsa ho 70 ° C. Latela mokhoa ka 1) ho qhalakanya MC ho lokisetsa slurry metsi a chesang; ebe o eketsa palo e setseng ea metsi a batang kapa metsi a leqhoa Ka har'a slurry ea metsi a chesang, pholisa motsoako ka mor'a ho susumetsa.
Mokhoa oa ho kopanya phofo: omileng o kopanya likaroloana tsa phofo tsa MC tse nang le likarolo tse lekanang kapa tse khōloanyane tsa metsoako e meng ea phofo ho li qhalakanya ka botlalo, ebe o eketsa metsi ho li qhaqha, ebe MC e ka qhibiliha ntle le agglomeration.
3. Organic solvent wetting method: qhalakanya kapa moisten MC ka solvent organic, tse kang ethanol, ethylene glycol kapa oli, ebe o eketsa metsi ho qhaqha. Ebe MC le eona e ka qhaloa hantle.
Tse hlano. Morero:
Sehlahisoa sena se sebelisoa haholo kahong ea moaho, thepa ea moaho, liphahlo tse qhalakaneng, li-wallpaper, li-additives tsa polymerization, tse tlosang pente, letlalo, enke, pampiri, joalo-joalo joalo ka li-thickeners, li-adhesives, tse bolokang metsi, li-agent tse etsang filimi, Excipients, jj. . Ka mohlala, e sebelisoa e le se tlamang, se teteaneng le se bolokang metsi ka thepa ea mohaho, e le ntho e etsang filimi le e teteaneng indastering ea ho roala, hape e sebelisoa haholo masimong a kang ho cheka peterole le indasteri ea letsatsi le letsatsi ea lik'hemik'hale tsa lik'hemik'hale. .
1. Indasteri ea kaho: E le moemeli oa ho boloka metsi le ho fokotsa seretse sa samente, e etsa hore seretse se pompehe. E sebelisoa e le setlamo sa plaster, samente, putty powder kapa lisebelisoa tse ling tsa mohaho ho ntlafatsa ho ata le ho lelefatsa nako ea ts'ebetso. E ka sebelisoa ho beha lithaele tsa ceramic, 'mabole, mokhabiso oa polasetiki, paste enhancer, hape e ka fokotsa bongata ba samente. Thepa ea ho boloka metsi ea HPMC e thibela slurry hore e se ke ea qhoma ka lebaka la ho omella kapele ka mor'a kopo, le ho matlafatsa matla ka mor'a ho thatafala.
2. Indasteri ea tlhahiso ea li-ceramic: e sebelisoa haholo e le tlamahano ha ho etsoa lihlahisoa tsa ceramic.
3. Indasteri ea pente: Joaloka motenya, ea dispersant le stabilizer indastering ea pente, e na le ts'ebelisano e ntle ea metsi kapa li-solvents tsa tlhaho. E le ho tlosa pente.
4. Khatiso ea enke: E le motenya, dispersant le stabilizer indastering ea enke, e na le tumellano e ntle ea metsi kapa li-solvents tsa organic.
5. Plastiki: e sebelisoa e le lisebelisoa tsa ho lokolla hlobo, li-softeners, lubricant, joalo-joalo.
6. Polyvinyl chloride: E sebelisoa e le dispersant tlhahiso ea polyvinyl chloride 'me ke moemeli ea ka sehloohong ea thusang bakeng sa ho lokisetsa PVC ka ho emisa polymerization.
7. Tse ling: Sehlahisoa sena se boetse se sebelisoa haholo ho letlalo, lihlahisoa tsa pampiri, ho boloka litholoana le meroho le indasteri ea masela.
8. Indasteri ea meriana: lisebelisoa tsa ho roala; lisebelisoa tsa filimi; lisebelisoa tsa polymer tse laolang lebelo bakeng sa litokisetso tsa ho lokolloa butle; li-stabilizers; mahlahana a emisang; li-binders tsa matlapa; thickeners. Likotsi tsa bophelo bo botle: sehlahisoa sena se bolokehile ebile ha se na chefo, 'me se ka sebelisoa e le lijo tse tlatselletsang , Ha ho mocheso, ha ho na ho teneha ha letlalo le ho kopana le mucous membrane. Ka kakaretso e nkoa e bolokehile (FDA1985), tekanyo e lumelletsoeng ea letsatsi le letsatsi ke 25mg/kg (FAO/WHO 1985), le lisebelisoa tsa tšireletso li lokela ho apesoa nakong ea ts'ebetso.
Tšusumetso ea tikoloho: Qoba ho akhela ka tšohanyetso ho baka tšilafalo ea moea ka lerōle le fofang.
Likotsi tsa 'mele le tsa lik'hemik'hale: Qoba ho kopana le mehloli ea mollo, 'me u qobe ho hlaha ha lerōle le leholo sebakeng se koetsoeng ho thibela likotsi tsa ho phatloha.
Ntho ena ha e le hantle e sebelisoa feela e le motenya, e seng molemo bakeng sa letlalo.
Nako ea poso: Nov-24-2021