Hydroxypropylmethylcellulose (HPMC) ke derivative ea cellulose e sebelisoang haholo liindastering tse fapaneng. Tšebeliso ea mantlha ea HPMC ke li-thickeners, stabilizers le emulsifiers indastering ea lijo, ea meriana le ea litlolo. HPMC e boetse e sebelisoa lekaleng la kaho e le tlatsetso ea samente, joalo ka ho koahela matlapa le li-capsules, hape e le tharollo ea mahlo. Lisebelisoa tsa mantlha tsa HPMC ke cellulose le li-reagents tsa lik'hemik'hale.
Cellulose:
Cellulose ke thepa e ka sehloohong e tala bakeng sa tlhahiso ea HPMC. Cellulose ke polymer ea tlhaho e fumanehang maboteng a lisele tsa semela mme ke polymer ea tlhaho e ngata ka ho fetisisa Lefatšeng. Thepa ea lik'hemik'hale ea selulose e tšoana le HPMC, e etsang hore e be thepa e loketseng ea tlhahiso ea HPMC. Cellulose e tsoa mehloling e fapaneng, ho kenyelletsa lehong, k'hothone le limela tse fapaneng.
Mohloli o atileng haholo oa cellulose o sebelisetsoang tlhahiso ea HPMC ke makhasi a lehong. Makhasi a lehong a tsoa lifateng tse bonolo tse kang spruce, pine le fir. Makhasi a lehong a sebelisoa ka lik'hemik'hale ho senya lignin le hemicellulose, ho siea cellulose e hloekileng. Joale selulose e hloekileng e soeufalitsoe ebe e hlatsuoa ho tlosa litšila leha e le life.
Cellulose e sebelisoang bakeng sa tlhahiso ea HPMC e tlameha ho ba ea boleng bo holimo le mehato e tiileng ea taolo ea boleng e tlameha ho lateloa ho netefatsa bohloeki ba selulose. Bohloeki ba cellulose bo bohlokoa kaha litšila li ka ama thepa ea sehlahisoa sa ho qetela.
Li-reagents tsa lik'hemik'hale:
Tlhahiso ea HPMC e hloka ts'ebeliso ea li-reagents tse fapaneng tsa lik'hemik'hale. Li-reagents tsa lik'hemik'hale tse sebelisoang tlhahiso ea HPMC li kenyelletsa propylene oxide, methyl chloride, sodium hydroxide, hydrochloric acid, joalo-joalo.
Propylene oxide e sebelisoa ho hlahisa hydroxypropyl cellulose (HPC), e ntan'o itšoara ka methyl chloride ho hlahisa HPMC. HPC e sebetsana le methyl chloride ho nkela tse ling tsa lihlopha tsa hydroxyl sebakeng sa ketane ea cellulose ka lihlopha tsa methoxy le hydroxypropyl, kahoo li theha HPMC.
Sodium hydroxide e sebelisoa tlhahiso ea HPMC ho eketsa boleng ba pH ba tharollo ea karabelo ho thusa ho qhala selulose.
Nakong ea ts'ebetso ea tlhahiso ea HPMC, hydrochloric acid e sebelisoa ho fetola boleng ba pH ba tharollo ea karabelo.
Li-reagents tsa lik'hemik'hale tse sebelisoang tlhahiso ea HPMC li tlameha ho ba le bohloeki bo phahameng, 'me maemo a karabelo a tlameha ho laoloa ka hloko ho netefatsa boleng ba sehlahisoa sa ho qetela.
ha re phethela:
Lisebelisoa tsa mantlha tsa HPMC ke cellulose le li-reagents tsa lik'hemik'hale. Cellulose, e nkiloeng mehloling e fapaneng e kenyelletsang lehong, k'hothone le limela tse fapaneng, ke lisebelisoa tse ka sehloohong tse tala bakeng sa tlhahiso ea HPMC. Lisebelisoa tsa lik'hemik'hale tse sebelisoang tlhahiso ea HPMC li kenyelletsa propylene oxide, methyl chloride, sodium hydroxide le hydrochloric acid. Tlhahiso ea HPMC e hloka mehato e tiileng ea taolo ea boleng ho netefatsa bohloeki ba thepa e tala le boleng ba sehlahisoa sa ho qetela. HPMC e sebelisoa haholo liindastering tse fapaneng 'me e na le mefuta e mengata ea likopo ka lebaka la thepa ea eona e ikhethang.
Nako ea poso: Sep-06-2023