1. Tšebeliso e ka sehloohong ea hydroxypropyl methylcellulose (HPMC) ke efe?
Karabo: HPMC e sebelisoa haholo linthong tsa kaho, liphahlo, li-resin tsa maiketsetso, lirafshoa, meriana, lijo, masela, temo, litlolo, koae le liindasteri tse ling. HPMC e ka aroloa ka sehlopha sa kaho, sehlopha sa lijo le sehlopha sa meriana ho latela sepheo. Hajoale, boholo ba lihlahisoa tsa lapeng ke tsa boemo ba kaho. Sebakeng sa kaho, phofo ea putty e sebelisoa ka bongata, hoo e ka bang 90% e sebelisetsoa putty powder, 'me e setseng e sebelisetsoa seretse sa samente le sekhomaretsi.
2. Ho na le mefuta e mengata ea hydroxypropyl methylcellulose (HPMC), 'me ke phapang efe ea tšebeliso ea bona?
Karabo: HPMC e ka aroloa ka mofuta oa hang-hang le mofuta oa ho qhibiliha o chesang. Lihlahisoa tsa mofuta oa hang-hang li hasana ka potlako metsing a batang ebe li nyamela ka metsing. Ka nako ena, mokelikeli ha o na viscosity hobane HPMC e qhalakanngoa feela metsing ntle le ho qhibiliha ha sebele. Hoo e ka bang metsotso e 2, viscosity ea mokelikeli e ntse e eketseha butle-butle, e etsa "viscous colloid" e hlakileng. Lihlahisoa tse chesang, ha li kopane le metsi a batang, li ka qhalana ka potlako metsing a chesang 'me tsa nyamela metsing a chesang. Ha mocheso o theohela ho mocheso o itseng, viscosity e tla hlaha butle-butle ho fihlela e etsa "viscous colloid" e hlakileng. Mofuta oa hot-melt o ka sebelisoa feela ka phofo ea putty le seretse. Ka sekhomaretsi sa metsi le pente, ho tla ba le ts'ebetso ea lihlopha 'me e ke ke ea sebelisoa. Mofuta oa hang-hang o na le mefuta e mengata e fapaneng ea lits'ebetso. E ka sebelisoa ka phofo ea putty le seretse, hammoho le sekhomaretsi sa metsi le pente, ntle le li-contraindications.
3. Mekhoa ea ho qhibiliha ea hydroxypropyl methylcellulose HPMC ke efe?
Karabo: Mokhoa oa ho qhibiliha ha metsi a chesang: Kaha HPMC ha e qhale metsing a chesang, HPMC e ka qhalakanngoa ka ho lekana metsing a chesang qalong, ebe e qhibiliha ka potlako ha e pholile. Mekhoa e 'meli e tloaelehileng e hlalosoa ka tsela e latelang:
1), eketsa 1/3 kapa 2/3 ea palo e hlokahalang ea metsi ka har'a setshelo, 'me ue chese ho 70 ° C, qhala HPMC ho latela mokhoa oa 1),' me u lokise slurry ea metsi a chesang; joale eketsa palo e setseng ea metsi a batang ho metsi a chesang a slurry, motsoako o ne o pholile ka mor'a ho hlohlelletsa.
Mokhoa oa ho kopanya phofo: kopanya phofo ea HPMC le bongata ba lintho tse ling tse phofo, kopanya ka botlalo le motsoako, ebe u eketsa metsi ho qhibiliha, ebe HPMC e ka qhibiliha ka nako ena ntle le ho kopana, hobane ho na le HPMC e nyenyane feela ho e 'ngoe le e' ngoe e nyenyane. hukung Powder, e tla qhibiliha hang hang ha e kopana le metsi. ——Baetsi ba phofo le seretse ba sebelisa mokhoa ona. [Hydroxypropyl methylcellulose (HPMC) e sebelisoa e le ntho e thibelang metsi le ho boloka metsi seretseng sa putty powder.
2) Kenya palo e hlokahalang ea metsi a chesang ka har'a sets'oants'o 'me ue chese ho isa ho 70°C. Hydroxypropyl methylcellulose e ile ea kenngoa butle-butle tlas'a ho sisinyeha butle-butle, qalong HPMC e ne e phaphametse holim'a metsi, 'me butle-butle e theha slurry, e neng e pholile tlas'a ho sisinyeha.
Nako ea poso: Dec-01-2022