HydroxypropypropyLese (HPMC)MmeMethylcellllll (MC)Na bobeli ba 'na le litlolo tse ngata li sebelisoa hangata indastering ea se fapaneng, ho kenyelletsa merafo, lijo, litlolo le kaho. Leha ba tšoana le, lisebelisoa tsena tse peli li na le thepa ea lik'hemik'hale tsa lik'hemik'hale tsa lik'hemik'hale.
1. Sebopeho sa lik'hemik'hale
Ka bobeli HPMC le MC ke li-moqapi tsa li-celluulose, empa phapanyetsano ea bohlokoa e bua ka lihlopha tsa lik'hemik'hale tse hokahaneng le mojali oa selefounu.
Methylcellllll (MC): Ho hlophisoa ka ho lokisa cellulose. Ts'ebetsong ena, lihlopha tsa methyl (-ch3) li hokahane le lihlopha tsa limolek'hule tsa hydroyl tsa limolek'hule tsa celdroulese. Toka ea methylation e fapana lipakeng tsa 20-30%, ho latela sehlopha sa MC, se susumetsang sello sa kelello le thepa e 'ngoe.
HydroxypropypropyLese (HPMC): Kimacell®hpmC ke e mongata e mongata. Ntle le ho lokisa methy, e fana ka maikutlo a a hydroxyproppy. Lihlopheng tsa Hydroxypropyl (-ch2choHhkl3) li tsebisoa molek'hulese ea cellulose, hammoho le lihlopha tsa methyl. Tekanyo ea hydroxypropylar le degree ea è
| Tšobotsi | Methylcellllll (MC) | HydroxypropypropyLese (HPMC) |
| Sebopeho sa lik'hemik'hale | Methylation ea cellulose | Methylation le hydropxxxpylation ea cellulose |
| Lihlopha tse sebetsang | Lihlopha tsa Methyl (-ch3) | Lihlopha tsa Methyl (-ch3) + Lihlopha tsa HydroxyproPyL (-ch2hohch3) |
| Degree of Singlution (DS) | 20-30% methylation | Fapana, ka methyl le hydropyLe maemo a sebaka a ho nka sebaka |
2. Fulubility
Fuubility ke e 'ngoe ea lintlha tsa bohlokoahali ha ho bapisa MC le hpmc. Khoebo ea lintho tsena ka bobeli ea selefouleses e itšetlehile ka boemo ba sebaka le mokhoa o ikhethileng oa litaba.
Methylcellllll (MC): Mc e qhibiliha ka metsing a chesang empa a etsa gel ea ho pholile. Thepa ena e ikhethang ea ho theha li-gels ha e futhumatsa le ho qeta ho ea sebakeng sa metsi ha ho pholile ke e 'ngoe ea litšobotsi tse bohlokoa ka ho fetisisa tsa MC. Ha e khante ka metsing a batang, empa e qhibiliha metsing a chesang ka holim'a mocheso o itseng oa C), 'me ts'ebetso ea bokhachane e fetotsoe.
HydroxypropypropyLese (HPMC): HpMC, ka lehlakoreng le leng, e qhibiliha ka metsing a batang le a chesang. Sena se etsa hore ho be le maemo a eketsehileng ho bapisoa le MC. Khoebo ea HPMC e susumetsoa ke mofuta oa sebaka sa ho nkeloa sebaka (karo ea methyl ho li-hydroxypropyl ka lihlopha tsa Hydroxypropity) le sehlopha sa Viscosity. Li-degree tse phahameng tsa sebaka se phahameng li tloaetse ho etsa HPMC e qhibiliha ka metsing ka lithemparetjha tse tlase.
| Fulubility | Methylcellllll (MC) | HydroxypropypropyLese (HPMC) |
| Laubili ka metsing | E qhibiliha ka metsing a chesang (grination ka ho futhumatsa) | E qhibiliha ka bobeli ba metsi a chesang le a batang |
| Thepa ea Gerlation | E etsa gel ha e pholile | Ha e thehe gel, e lula e qhibiliha lithemparetjha tsohle |
3. Viscosity
Litšoantšiso li bapala karolo ea bohlokoa likolong tse ngata, haholo-holo indastering ea melisa le ea lijo.
Methylcellllll (MC)Viscos of Kimacell®mc Tharollo ke ea its'etleha ka mocheso. Viscosity e eketseha ha o futhumatsa, 'me se bonts'a ntho e' ngoe ea borila. Tekanyo ea ho nka karolo e boetse e ama viscosion, ka maemo a ho nkang sebaka ka kakaretso a fella ka pono e phahameng.
HydroxypropypropyLese (HPMC): HPMC ka kakaretso e na le boemo bo sa pheleng haholoanyane Viscosity ba bapisoang le MC. Litaba tsa HPMC le tsona li susumetsoa ke boemo ba nke ke karolo ea lithemparetjha. Ntle le moo, HPMC e ka tsamaisana le li-viscosion tse fapaneng, ho tloha ho tlase ho ea holimo, ho latela kopo e reretsoeng.
| Viscosity | Methylcellllll (MC) | HydroxypropypropyLese (HPMC) |
| Boitšoaro ba liketsahalo tsa pono | E eketseha ka ho futhumatsa (genation) | Lipaleng tse tsitsitseng tsa pono e tsitsitseng ea lithemparetjha tse fapaneng |
| Taolo holim'a pono | Taolo e lekanyelitsoeng holim'a pono | Taolo e kholo ho feta Viscosity e thehiloeng ho sehlopha le boemo ba sebaka |
4. Likopo
Ka bobeli MC le HpMC li sebelisoa haholo ho li-pharmatoctical, lijong, empa thepa e ikhethang ea e mong le e mong ea e etsa tse ling tsa bohlokoa bakeng sa likopo tse itseng.
Methylcellllll (MC):
Pharmaceutical: Mc hangata e sebelisoa e le mojaro, ho senyeha, le moemeli oa ho koahela le limpho tsa boleng bo holimo ka lebaka la thepa ea eona ea gerties. E boetse e sebelisoa ka mekhoa e laoloang e laoloang.
Indasteri ea lijo: Mc e sebelisoa e le lijo tse nang le lijo, emolfier le tsitla. Thepa ea eona ea gel e etsang e bohlokoa ho etsa lihlahisoa tse kang ice cream, liaparo tsa salate le lihlahisoa tsa ho baka.
Li-cosmetics: Mc e sebelisoa ho li-cosmetics bakeng sa eona ea ho toba, ho utloahala ebile e tiisa lihlahisoa tse fapaneng le li-loution, li-shampoos le litlolo.
HydroxypropypropyLese (HPMC):
Pharmaceutical: HPMC e sebelisoa haholo joalo ka moemeli oa tokiso le ea ho lokolloa tse laoloang. E boetse e sebelisoa ka litharollo tsa lifate tsa ophthalric e le lubricant le litsamaiso tsa lithethefatsi tsa Gel tse thehiloeng ho gel.
Indasteri ea lijo: HPMC e sebelisoa ho baking e sa lefelloeng e sa lefelloeng, kaha e ntse e etsisa bokhabane le ho hlaka ha glutuen e le hlama hlama. E boetse e sebelisoa e le mokhoa o tsitsitseng le emulifier lijong tse fapaneng tse sebelisoang.
Kaho: HPMC e sebelisoa e le molaoli ea samente, polasetiki le liperere tsa tale. Ho ntlafatsa bokhoni, ho boloka metsi le ho tšoarella.
| Kopo | Methylcellllll (MC) | HydroxypropypropyLese (HPMC) |
| Pharmaceutical | Tlama, ho senyeha hoa bokhabane, moemeli oa koae | Tlatsetso, e laoloang e laoloang, e laoloang |
| Indasteri ea lijo | Emuckener, Emulfifier, Stabilizer | Gluten-Free Baking, Stabilizer, Emulfifier |
| Li-cosmetics | Emuckener, Emulfifier, Stabilizer | Thckener, Stabilizer, Emusfiyeer |
| Kaho | Ka seoelo o sebelisitsoeng | Ofisiri ea samente, Plaster, Madhes |
5. Thepa e meng
Hygroscopicity: Hpmc hangata e ngata haholo (ho hohela metsi) ho feta MC, e etsang hore e be thuso ho lits'ebeliso moo ho tla ba le bolokolohi ba mongobo.
Ho tsitsa ho hoama ha futhumatsang: Mc o hloka ho bonts'a botsitso ba futhumatsang bo botle ka lebaka la thepa ea eona ea borena. HPMC, ha e ntse e tsitsitse sebakeng sa mocheso o mongata, e kanna ea se ke oa fana ka phello e ts'oanang ea bokhachane e tšoanang le ea tlhaho e le MC.
6. Kakaretso ea Phapang
| Tšobotsi | Methylcellllll (MC) | HydroxypropypropyLese (HPMC) |
| Sebopeho sa lik'hemik'hale | Lihlopha tsa Methyl li hokahantsoe le cellulose | Lihlopheng tsa Methyl le tsa Hydropyl li hokahantsoe le celbulose |
| Fulubility | E qhibiliha ka metsing a chesang, mefuta ea li-gels | Ho qhibiliha ka bobeli ba metsi a batang le a chesang |
| Thepa ea Gerlation | E etsa gel ho pholile | Ha ho na hola, e lula e qhibiliha |
| Viscosity | Mocheso o its'etleha, gels ka ho futhumatsa | Litšoantšo tse tsitsitseng tsa Viscosity ho pholletsa le mocheso |
| Likopo | Merima, lijo, litlolo | Meriana, lijo (gluten-free), litlolo, kaho |
| Hygroscopicity | Tlase ho hpmc | Phahameng, e hohela mongobo o mongata |
Ha bobeli le bonaHpmcMmeMCNa lisitimal tse tsoang ka mmonsulose li na le lits'ebetso tse fetang tse fetang tsa lik'hemik'hale le thepa ea tsona li etsa hore ba be le mekhoa e fapaneng. MC e bohlokoa haholo-holo likopo tse ruang molemo thepa ea bona ea botala, ha ho tsitsipalla ho phahameng le ho tsitsipalla ho etsa hore ho be le maemo indasteri Ho utloisisa liphapang tsena ho thusa ho khetha thepa e nepahetseng bakeng sa lits'ebetso tse khethehileng.
Nako ea ho romella: Jan-27-2025