Focus on Cellulose ethers

Pharmaceutical grade HPMC

Pharmaceutical grade HPMC

Pharmaceutical grade HPMC Hydroxypropyl methylcellulose e tšoeu kapa e le milky white, ha e na monko, ha e latsoehe, phofo ea fibrous kapa granule, tahlehelo ea boima ba 'mele ha e omisoa ha e fete 10%, e qhibiliha metsing a batang empa e se metsi a chesang, butle-butle metsing a chesang, ho ruruha, peptization le ho theha viscous colloidal solution, e fetohang tharollo ha e pholile, 'me e fetoha gel ha e futhumala. HPMC ha e qhibilihe ka har'a ethanol, chloroform le ether. E qhibiliha ka har'a motsoako o motsoako oa methanol le methyl chloride. E boetse e qhibiliha ka har'a motsoako o tsoakiloeng oa acetone, methyl chloride le isopropanol le metsoako e meng ea tlhaho. Tharollo ea eona ea metsi e ka mamella letsoai (tharollo ea eona ea colloidal ha e senngoe ke letsoai), 'me pH ea 1% ea tharollo ea metsi ke 6-8. Foromo ea molek'hule ea HPMC ke C8H15O8-( C10H18O6) -C815O, 'me boima ba molek'hule bo ka bang 86,000.

 

Tlhaloso ea Lik'hemik'hale

HPMC ea meriana

Tlhaloso

HPMC 60E( 2910) HPMC 65F(2906) HPMC 75K( 2208)
Mocheso oa mocheso oa gel (℃) 58-64 62-68 70-90
Methoxy (WT%) 28.0-30.0 27.0-30.0 19.0-24.0
Hydroxypropoxy (WT%) 7.0-12.0 4.0-7.5 4.0-12.0
Viscosity(cps, 2% Tharollo) 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000

 

Sehlopha sa Sehlahisoa:

HPMC ea meriana

Tlhaloso

HPMC 60E( 2910) HPMC 65F(2906) HPMC 75K( 2208)
Mocheso oa mocheso oa gel (℃) 58-64 62-68 70-90
Methoxy (WT%) 28.0-30.0 27.0-30.0 19.0-24.0
Hydroxypropoxy (WT%) 7.0-12.0 4.0-7.5 4.0-12.0
Viscosity(cps, 2% Tharollo) 3, 5, 6, 15, 50, 100, 400,4000, 10000, 40000, 60000,100000,150000,200000

 

 

Kopo

Kopo ea Pharma Excipients Pharmaceutical Grade HPMC Tekanyetso
Bongata bo Laxative 75K4000,75K100000 3-30%
Litlolo, li-gel 60E4000,75K4000 1-5%
Boitokisetso ba Mahlo 60E4000 01.-0.5%
Litokisetso tsa Marotholi a Mahlo 60E4000 0.1-0.5%
Moemeli ea Emisang Mosebetsi 60E4000, 75K4000 1-2%
Li-antacids 60E4000, 75K4000 1-2%
Matlapa Binder 60E5, 60E15 0.5-5%
Kopano Metsi Granulation 60E5, 60E15 2-6%
Liaparo tsa Letlapa 60E5, 60E15 0.5-5%
Laola Release Matrix 75K100000,75K15000 20-55%

 

Likarolo le Melemo:

HPMC e na le ho qhibiliha ho hoholo ha metsi metsing a batang. E ka qhibiliha ka tharollo e hlakileng ka ho hlohlelletsa hanyenyane metsing a batang. Ho fapana le hoo, ha e le hantle ha e qhibilihe metsing a chesang a ka holimo ho 60 ℃ 'me e ka ruruha feela. Ke ether e seng ea ionic cellulose. Tharollo ea eona ha e na tefiso ea ionic, ha e sebelisane le letsoai la tšepe kapa metsoako ea ionic, 'me ha e sebetsane le lisebelisoa tse ling tse tala nakong ea ho lokisetsa; e na le matla a anti-sensitivity, 'me ha tekanyo ea ho nkela sebaka mohahong oa limolek'hule e ntse e eketseha, eona E hanyetsana le ho kula le ho tsitsisa haholoanyane; e boetse e na le inert metabolism. Joaloka motsoako oa meriana, ha e na metabolized kapa ho kenngoa. Ka hona, ha e fane ka mocheso meriana le lijong. Ha e na lik'halori tse tlase, ha e na letsoai, 'me ha e na letsoai ho batho ba nang le lefu la tsoekere. Lithethefatsi le lijo tse fapaneng li na le ts'ebetso e ikhethang; e batla e tsitsitse ho li-acids le alkalis, empa haeba boleng ba PH bo feta 2 ~ 11 mme bo angoa ke mocheso o phahameng kapa o na le nako e telele ea ho boloka, viscosity ea eona e tla fokotseha; tharollo ea eona ea metsi e ka fana ka ts'ebetso ea Surface, e bonts'a tsitsipano e leka-lekaneng holim'a metsi le litekanyetso tsa tsitsipano ea sefahleho; e na le emulsification e atlehang tsamaisong ea mekhahlelo e 'meli, e ka sebelisoa e le stabilizer e sebetsang hantle le colloid e sireletsang; tharollo ea eona ea metsi e na le thepa e babatsehang ea ho etsa filimi, 'me ke letlapa le pilisi Ntho e ntle ea ho roala. Seaparo sa filimi se entsoeng ke sona se na le melemo ea ho se be le mebala le ho ba thata. Ho eketsa glycerin ho ka boela ha ntlafatsa polasetiki ea eona.

 

Sephutheloana

Pakete e tloaelehileng ke 25kg / Fibre drum 

20'FCL: lithane tse 9 tse nang le palletized; Lithane tse 10 tse sa phethoang.

40'FCL: lithane tse 18 tse nang le palletized; Lithane tse 20 tse sa phethoang.

 

Polokelo:

E boloke sebakeng se phodileng, se omileng se ka tlase ho 30 ° C mme e sirelelitsoe khahlanong le mongobo le ho hatella, kaha thepa ke thermoplastic, nako ea polokelo ha ea lokela ho feta likhoeli tse 36.

                                                                          

Lintlha tsa polokeho:                                                                         

Lintlha tse ka holimo li tsamaellana le tsebo ea rona, empa u se ke ua lokolla bareki ka ho li hlahloba ka hloko hang ha u li fumana. Ho qoba mefuta e fapaneng ea tlhahiso le lisebelisoa tse fapaneng tse tala, ka kopo etsa liteko tse ngata pele u li sebelisa.

 


Nako ea poso: Nov-26-2023
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