Kakaretso ea HPMC

Hydroxypropyl methyl cellulose (HPMC) ke cellulose ether e sebelisoang haholo liindastering tse fapaneng tse kang kaho, meriana, lijo le tlhokomelo ea motho. HPMC ke non-ionic metsi-qhibilihang polymer e nkiloeng ho selulose. E entsoe ka ho arabela selulose ka propylene oxide le methyl chloride.

HPMC ke polymer e feto-fetohang e bonts'ang mefuta e mengata ea thepa ea 'mele le ea lik'hemik'hale. E fumaneha ka limaraka tse fapaneng ka litekanyo tsa limolek'hule tse fapaneng, likhato tsa substitution, le viscosity. Thepa ena e etsa hore HPMC e loketse lits'ebetso tse fapaneng liindastering tse fapaneng.

Thepa ea 'Mele ea HPMC:

1. Solubility: HPMC e qhibiliha ka metsing, empa ho qhibiliha ha eona ho itšetlehile ka tekanyo ea sebaka, boima ba molek'hule le mocheso.
2. Botsitso ba mocheso: HPMC e bonts'a botsitso bo botle ba mocheso mme e khona ho mamella mocheso ho fihla ho 200 ° C.
3. Ho etsa lifilimi: HPMC e ka etsa lifilimi tse nang le matla a matle le ho tenyetseha.
4. Adhesion: HPMC e bonts'a thepa e ntle ea ho khomarela 'me e ka sebelisoa e le sekhomaretsi lits'ebetsong tse fapaneng.
5. Thepa ea Rheological: HPMC e bonts'a boits'oaro ba pseudoplastic, ho bolelang hore viscosity ea eona e fokotseha ka sekhahla sa ho kuta.

Lik'hemik'hale tsa HPMC:

1. Hydrophilicity: HPMC e na le tlhaho ea hydrophilic 'me e ka monya metsi ho feta boima ba eona hararo.
2. Khanyetso ea lik'hemik'hale: HPMC e bonts'a khanyetso e ntle ea lik'hemik'hale 'me e hanana le litharollo tsa asiti, alkali le letsoai.
3. Biodegradability: HPMC e ka senyeha 'me ha e senye tikoloho.

Lisebelisoa tsa HPMC:

1. Indasteri ea Kaho: HPMC e sebelisoa haholo indastering ea kaho joalo ka motsoako oa samente. E eketsoa ka samente ho ntlafatsa ts'ebetso ea eona, ho boloka metsi, le thepa ea ho khomarela. HPMC e boetse e sebelisoa ho likhomaretsi tsa lithaele, seretse, le stucco ho ntlafatsa ts'ebetso ea tsona.
2. Indasteri ea Litlhare: HPMC e sebelisoa indastering ea meriana e le setlamo, se senyang, le se teteaneng. E sebelisoa mefuteng ea li-tablet ho ntlafatsa ho senyeha ha letlapa le thepa ea ho qhibiliha. HPMC e boetse e sebelisoa ho li-topical formulations joalo ka litlolo, litlolo, le li-gel joalo ka motenya le emulsifier.
3. Indasteri ea Lijo: HPMC e sebelisoa indastering ea lijo e le motenya, emulsifier, le stabilizer. E eketsoa ho lihlahisoa tsa lijo tse kang li-sauces, sopho le litlolo ho ntlafatsa sebopeho sa tsona le botsitso.
4. Indasteri ea Tlhokomelo ea Motho: HPMC e sebelisoa ho lihlahisoa tsa tlhokomelo ea motho joalo ka li-shampoo, li-conditioner, le litlolo e le setenya le emulsifier. E boetse e sebelisoa ka litlolo e le filimi-former le binder.
5. Liindasteri tse ling: HPMC e sebelisoa liindastering tse ling tse fapaneng joalo ka liindasteri tsa pente, enke, le masela joalo ka seteifatsi le botsitso.

Mefuta ea HPMC:

1. Low Viscosity HPMC: Viscosity e tlase HPMC e na le boima ba molek'hule bo ka bang 10,000 'me e sebelisoa lits'ebetsong tse hlokang viscosity e tlase, joalo ka lintja le li-inks tsa khatiso.
2. Medium Viscosity HPMC: Viscosity e mahareng HPMC e na le boima ba molek'hule bo ka bang 50,000 mme e sebelisoa lits'ebetsong tse hlokang viscosity e itekanetseng, joalo ka meriana le lihlahisoa tsa tlhokomelo ea motho.
3. High Viscosity HPMC: High viscosity HPMC e na le boima ba molek'hule bo ka bang 100,000 'me e sebelisoa lits'ebetsong tse hlokang viscosity e phahameng, joalo ka thepa ea kaho le lihlahisoa tsa lijo.

Melemo ea ho sebelisa HPMC:

1. Ho boloka metsi: HPMC e ntlafatsa ho bolokoa ha metsi thepa ea kaho, e leng se fellang ka ts'ebetso e ntle le ts'ebetso e ntlafetseng.
2. Ho khomarela: HPMC e ntlafatsa ho khomarela thepa ea kaho, e leng se etsang hore ho be le maqhama a betere le ho tšoarella ho ntlafetseng.

Qetello

HPMC ke ether ea selulose e sebetsang ka mefuta-futa e sebelisoang haholo e fumanehang liindastering tse fapaneng. Lintho tsa eona tse ikhethang, tse kang ho teteka, ho boloka metsi, le ho etsa lifilimi, li etsa hore e be tlatsetso e ratoang indastering ea kaho, ea meriana, ea lijo le ea tlhokomelo ea botho. Ha tlhoko ea HPMC e ntse e hola, bafuputsi ba ntse ba hlahloba lits'ebetso tse ncha le ho nts'etsapele limaraka tse ncha tsa HPMC ka thepa e ntlafalitsoeng ho fihlela litlhoko tse ikhethang tsa liindasteri tse fapaneng.