Hydroxypropyl methylcellulose (HPMC) ke polymer e sebetsang ka bongata e sebelisoang liindastering tse fapaneng, ho kenyeletsoa meriana, kaho, lijo le litlolo. Thepa e 'ngoe ea bohlokoa e amang haholo ho tšoaneleha ha eona ke viscosity. Viscosity e bolela ho hanyetsa ha mokelikeli ho phalla 'me e bapala karolo ea bohlokoa ho khethollang ts'ebetso le ts'ebetso ea HPMC lits'ebetsong tse fapaneng.
1. Utloisisa HPMC:
Hydroxypropylmethylcellulose (HPMC) ke semi-synthetic water-soluble polymer e nkiloeng ho selulose.
Ka lebaka la thepa ea eona e ikhethang, hangata e sebelisoa e le motenya, stabilizer, filimi ea pele le sekhomaretsi.
HPMC e fumaneha ka limaraka tse fapaneng, e 'ngoe le e 'ngoe e na le maemo a fapaneng a viscosity, e amang ts'ebetso ea eona lits'ebetsong tse fapaneng.
2. Lits'ebetso tsa Pharmaceutical:
Lefapheng la meriana, HPMC e sebelisoa haholo ka ho roala letlapa, liforomo tse laoloang tsa tokollo le ho emisoa.
Viscosity e bapala karolo ea bohlokoa ho laoleng botenya le ho ts'oana ha letlapa, ho netefatsa tokollo e nepahetseng ea lithethefatsi le bioavailability.
The viscosity ea HPMC e boetse e ama litšoaneleho tsa phallo ea ho emisoa le botsitso ba tlhahiso, kahoo e ama phepelo ea lithethefatsi le ho latela mokuli.
3.Indasteri ea kaho:
HPMC e sebelisoa haholo indastering ea kaho e le setsi sa ho tenya bakeng sa lirekere tse thehiloeng ho samente, likhomaretsi tsa lithaele le lipolasetere.
Viscosity e ama ts'ebetso ea ts'ebetso le khanyetso ea sag ea metsoako ea seretse, ho netefatsa ho khomarela hantle le ho fokotsa litšila tsa thepa nakong ea kaho.
Ka ho lokisa viscosity ea liforomo tsa HPMC, lihahi li ka fihlela botsitso bo lakatsehang le litšoaneleho tsa ts'ebetso, kahoo ba ntlafatsa boleng ba merero ea bona ea kaho.
4. Indasteri ea lijo le lino:
Indastering ea lijo le lino, HPMC e sebelisoa e le setenya, emulsifier le stabilizer lihlahisoa tse fapaneng tse kenyelletsang lisoso, sopho le mefuta e meng ea lebese.
Viscosity e ama sebopeho, molomo le botsitso ba lijo, ho netefatsa thepa e nepahetseng ea kutlo le bophelo ba sethala.
Baetsi ba lijo ba khetha ka hloko limaraka tsa HPMC tse nang le maemo a hlakileng a viscosity ho fihlela litlhoko tse lakatsehang tsa sehlahisoa le ho sebetsa.
5. Litlolo le lihlahisoa tsa tlhokomelo ea motho ka mong:
HPMC e sebelisoa e le setei se teteaneng le ho etsa lifilimi ho litlolo le lihlahisoa tsa tlhokomelo ea motho joalo ka litlolo, litlolo le li-shampoo.
Viscosity e bapala karolo ea bohlokoa ho laola botsitso ba sehlahisoa, ho ata le botsitso, ho matlafatsa boiphihlelo ba basebelisi le ts'ebetso ea sehlahisoa.
Baetsi ba litlolo ba itšetleha ka HPMC e nang le li-profiles tsa viscosity tse ikhethileng ho fihlela rheology e lakatsehang le litšoaneleho tsa kutlo mekhoeng ea bona.
6. Bohlokoa ba taolo ea viscosity:
Taolo e nepahetseng ea viscosity e bohlokoa ho fihlela litlhoko tse ikhethileng tsa lits'ebetso tse fapaneng.
Baetsi ba fana ka mefuta e fapaneng ea limaraka tsa HPMC tse nang le maemo a fapaneng a viscosity, e lumellang baetsi ba liforomo ho khetha sehlopha se ba loketseng hantle bakeng sa ts'ebeliso ea bona.
Tekanyo e nepahetseng ea viscosity le sebopeho sa rheological li thusa baetsi ba lihlahisoa ho ntlafatsa libopeho le ho netefatsa ts'ebetso e tsitsitseng ea sehlahisoa le boleng.
7. Lintlha tse amang viscosity:
Lintlha tse 'maloa, ho kenyelletsa mahloriso a polymer, boima ba limolek'hule, tekanyo ea ho fetola, le mocheso, li ka ama viscosity ea tharollo ea HPMC.
Ho utloisisa kamano lipakeng tsa lintlha tsena le viscosity ho bohlokoa ho theha lihlahisoa tsa HPMC tse nang le litšobotsi tse lakatsehang tsa ts'ebetso.
Viscosity ke parameter ea bohlokoa e ka amang ts'ebetso le ts'ebetso ea HPMC lits'ebetsong tse fapaneng.
Liindastering tsa meriana, tsa kaho, tsa lijo, tsa litlolo le tsa tlhokomelo ea motho, taolo e nepahetseng ea viscosity e bohlokoa ho fihlela litlhoko tse ikhethileng tsa tlhahiso le ho fihlela litšobotsi tse lakatsehang tsa sehlahisoa. Ka ho utloisisa bohlokoa ba viscosity le phello ea eona lits'ebetsong tsa HPMC, bahlahisi le baetsi ba lihlahisoa ba ka ntlafatsa litlolo ho ntlafatsa ts'ebetso ea sehlahisoa, boleng le khotsofalo ea bareki. Viscosity ke ntlha ea bohlokoa ho khethollang ts'ebetso le ts'ebetso ea HPMC lits'ebetsong tse fapaneng. Taolo ea eona e hlokolosi le kutloisiso li bohlokoa ho fihlela litšobotsi tse lakatsehang tsa sehlahisoa le ho netefatsa katleho ho pholletsa le liindasteri.
Nako ea poso: Feb-29-2024