Hydroxypropyl Methylcellulose (HPMC) ke ether ea selulose e fetotsoeng e sebelisoang haholo litokisetsong tsa meriana, li-additives tsa lijo, thepa ea mohaho, litlolo le masimo a mang. HPMC e na le botenya, ho etsa lifilimi, ho khomarela le lintho tse ling. Kamano pakeng tsa viscosity le mahloriso a tharollo ea metsi a eona e bohlokoa haholo bakeng sa lits'ebetso tse fapaneng.
Litšobotsi tsa viscosity tsa tharollo ea metsi a HPMC
Litšobotsi tsa mantlha
HPMC e etsa tharollo ea viscous e bonaletsang kapa e feto-fetohang ka mor'a ho qhibiliha ka metsing. Viscosity ea eona ha e amehe feela ke mahloriso a HPMC, empa hape ke lintlha tse kang boima ba limolek'hule, mofuta oa substituent le mocheso oa tharollo.
Boima ba limolek'hule: Ha boima ba limolek'hule ba HPMC bo le boholo, bo phahamisa viscosity ea tharollo. Sena se bakoa ke hore limolek'hule tsa macromolecules li etsa sebopeho se rarahaneng haholoanyane sa tharollo, se eketsang khohlano lipakeng tsa limolek'hule.
Mofuta o mong: Karo-karolelano ea methoxy le hydroxypropoxy e ama ho solubility le viscosity ea HPMC. Ka kakaretso, ha methoxy content e phahame, ho qhibiliha ha HPMC ho molemo le viscosity ea tharollo le eona e phahame.
Kamano pakeng tsa mahloriso le viscosity
Mokhahlelo oa tharollo ea dilute:
Ha mahloriso a HPMC a le tlase, tšebelisano pakeng tsa limolek'hule e fokola 'me tharollo e bontša thepa ea mokelikeli oa Newtonian, ke hore, viscosity ha e le hantle e ikemetse ho sekhahla sa ho kuta.
Mothating ona, viscosity ea tharollo e eketseha ka mokhoa o ts'oanang le ho tsepamisa mohopolo. Kamano ena ea mela e ka hlalosoa ka mokhoa o bonolo oa viscosity equation:
| Khokahano (%) | Viscosity (mPa·s) |
| 0.5 | 100 |
| 1.0 | 300 |
| 2.0 | 1000 |
| 5.0 | 5000 |
| 10.0 | 20000 |
E ka bonoa ho tsoa ho data hore viscosity ea tharollo ea metsi ea HPMC e eketseha haholo ka keketseho ea mahloriso. Khōlo ena e tla hlaha kerafong e le moepa o ntseng o phahama, haholo-holo libakeng tsa mahloriso a phahameng.
Lintho tse susumetsang
Phello ea mocheso
Mocheso o na le phello e kholo ho viscosity ea tharollo ea HPMC. Ka kakaretso, ho eketseha ha mocheso ho fokotsa viscosity ea tharollo. Lebaka ke hobane mocheso o ntseng o eketseha o baka ho sisinyeha ha molek'hule le ho fokolisa tšebelisano lipakeng tsa liketane tsa limolek'hule, ka hona ho fokotsa viscosity.
Phello ea sekhahla sa ho kuta
Bakeng sa litharollo tse phahameng tsa HPMC, viscosity e boetse e angoa ke sekhahla sa ho kuta. Ka litekanyetso tse phahameng tsa ho kuta, mokhoa oa liketane tsa limolek'hule o fetoha o tsitsitseng mme ho ferekana ka hare ho fokotseha, ho fella ka ho fokotseha ho bonahalang ha viscosity ea tharollo. Ketsahalo ena e bitsoa ho kuta moriri.
Lisebelisoa
Litokisetsong tsa meriana, HPMC e atisa ho sebelisoa ka liphahlo tsa letlapa, liforomo tsa litekanyetso tsa tokollo e tsitsitseng, le li-thickeners. Ho utloisisa hore na viscosity ea litharollo tsa metsi tsa HPMC e fetoha joang ka mahloriso ho bohlokoa bakeng sa ho rala litlolo tse nepahetseng tsa lithethefatsi. Mohlala, ka ho roala letlapa, mahloriso a loketseng a HPMC a ka etsa bonnete ba hore mokelikeli oa ho roala o na le viscosity e lekaneng ho koahela bokaholimo ba letlapa, ha o ntse o sa phahame haholo hoo ho seng thata ho o tšoara.
Indastering ea lijo, HPMC e sebelisoa e le setenya le se tsitsitseng. Ho utloisisa kamano lipakeng tsa mahloriso le viscosity ho ka thusa ho tseba maemo a nepahetseng ho netefatsa tatso le sebopeho sa lijo.
The viscosity ea HPMC aqueous solution e na le kamano e ntle e ntle le mahloriso. E bonts'a keketseho e lekanang sethaleng sa tharollo ea dilute le keketseho e hlakileng ea khatello e phahameng. Sebopeho sena sa viscosity se bohlokoa lits'ebetsong tse fapaneng tsa indasteri, 'me ho utloisisa le ho laola liphetoho tsa viscosity ea HPMC ho bohlokoa haholo bakeng sa ntlafatso ea ts'ebetso le ntlafatso ea boleng ba sehlahisoa.
Nako ea poso: Jul-08-2024