Tsepamisa maikutlo ho Cellulose ethers

HPMC e ntlafatsa viscosity ea likhomaretsi joang?

Hydroxypropyl methylcellulose (HPMC) ke polymer ea bohlokoa e qhibilihang ka metsing e sebelisoang haholo indastering ea kaho, ea meriana, ea lijo le ea litlolo, haholo-holo lefapheng la li-adhesives. Taolo ea viscosity ea HPMC e bohlokoa ts'ebetsong ea sehlahisoa. bohlokoa. Ho ntlafatsa viscosity ea HPMC ka li-adhesives ho ka finyelloa ka ho fetola thepa ea eona ea 'mele le ea lik'hemik'hale, hammoho le ho ntlafatsa sebopeho le tikoloho ea kopo.

1. Fetola boima ba molek'hule ea HPMC
The viscosity ea HPMC haholo-holo itšetlehile ka boima ba eona ba molek'hule. Ka kakaretso, ha boima ba limolek'hule bo le boholo, ho na le viscosity e phahameng. Ka ho khetha HPMC e nang le boima bo nepahetseng ba limolek'hule, viscosity ea sekhomaretsi e ka laoloa ka katleho. Ka kakaretso, HPMC e nang le boima bo phahameng ba limolek'hule e tla eketsa viscosity ea sekhomaretsi, empa hape e tla ama phallo le ts'ebetso. Ka hona, tekano lipakeng tsa viscosity le operability e hloka ho fumanoa lits'ebetsong tse sebetsang.

2. Laola tekanyo ea ho kenya sebaka sa HPMC
HPMC ke sehlahisoa se fumanoang ho tsoa ho methylcellulose ka karabelo ea karolo ea hydroxypropylation. Tekanyo ea eona ea ho nkela sebaka (ke hore, tekanyo ea ho kenya sebaka sa hydroxypropyl le lihlopha tsa methyl) e na le tšusumetso e kholo ho viscosity. Likhato tse phahameng tsa ho nka sebaka ka kakaretso li fokotsa viscosity ea HPMC, athe likhato tse tlase tsa ho nka sebaka li eketsa viscosity. Ka hona, ka ho fetola tekanyo ea ho kenya sebaka sa HPMC, taolo e sebetsang ea viscosity e ka finyelloa. Maemong a fapaneng a ts'ebeliso, HPMC e nang le likhato tse fapaneng tsa phetisetso e kanna ea hlokahala ho fihlela litlhoko tsa ts'ebetso ea sekhomaretsi.

3. Taolo ea mocheso oa ho qhibiliha
The solubility le viscosity ea HPMC li amana haufi-ufi le mocheso. Ka kakaretso, HPMC e na le viscosity e phahameng ha e qhibiliha ka mocheso o tlase. Ka ho ntlafatsa mocheso oa ho qhibiliha oa HPMC nakong ea ho lokisetsa sekhomaretsi, viscosity ea sehlahisoa sa ho qetela e ka fetoloa. Ka mohlala, ho qhibiliha HPMC ka mocheso o phahameng ho ka etsa hore ho be le viscosity e tlaase ea pele, empa butle-butle ho eketseha ha viscosity ha mocheso o fokotseha. Ka hona, ka ho laola mocheso nakong ea ts'ebetso ea kaho, phetoho e matla ea viscosity e ka finyelloa.

4. Eketsa thickener
Ka mokhoa oa sekhomaretsi oa HPMC, ho eketsa palo e lekaneng ea motenya ho ka eketsa viscosity ka katleho. Li-thickeners tse tloaelehileng li kenyelletsa xanthan gum, carbomer, derivatives ea cellulose, joalo-joalo. Li-thickeners tsena li sebetsa ka mokhoa o ts'oanang le HPMC ho matlafatsa viscosity ka kakaretso ea sekhomaretsi. Ho phaella moo, li-thickeners li ka boela tsa ntlafatsa botsitso le khanyetso ea sag ea sekhomaretsi, e leng se fanang ka ts'ebetso e ntle ea ts'ebeliso.

5. Fetola mahloriso a tharollo ea HPMC
Motsoako oa tharollo ea HPMC metsing o na le tšusumetso e tobileng ho viscosity. Ha khatello ea kelello e phahame, e na le viscosity e kholoanyane. Lits'ebetsong tse sebetsang, viscosity ea sekhomaretsi e ka fetoloa habonolo ka ho laola khatello ea tharollo ea HPMC. Ka mohlala, ha u lokisetsa sekhomaretsi, viscosity e ka eketsoa ka ho eketsa butle-butle palo ea HPMC, kapa viscosity e ka fokotsoa ka ho hlapolla.

6. Recipe optimization
Viscosity ea sekhomaretsi sa HPMC ha e itšetlehe feela ka litšoaneleho tsa HPMC ka boeona, empa hape e amana haufi-ufi le tsamaiso eohle ea tlhahiso. Ka ho ntlafatsa mefuta le likarolo tsa likarolo tse ling ka foromo, joalo ka li-fillers, co-solvents, stabilizers, joalo-joalo, viscosity e ka fetoloa hantle. Mohlala, ho eketsa bongata ba filler ka nepo ho ka eketsa viscosity, empa ho tlatsa haholo ho ka etsa hore sekhomaretsi se be le mokelikeli o fokolang mme sa etsa hore ho be thata ho se sebelisa. Ka hona, moralo o nepahetseng oa foromo ke senotlolo sa ho ntlafatsa viscosity ea HPMC.

7. Phetoho ea boleng ba pH
The viscosity ea HPMC e boetse e angoa ke pH ea tharollo. Ka har'a mefuta e itseng, viscosity ea HPMC e fetoha ka boleng ba pH. Ka kakaretso, HPMC e bonts'a viscosity e phahameng ka ho se nke lehlakore ho ea libakeng tse fokolang tsa alkaline, ha tlas'a maemo a matla a acidic kapa alkaline, viscosity e ka fokotseha haholo. Ka hona, ka ho fetola pH ea sekhomaretsi, taolo ea viscosity e ka finyelloa. Mohlala, lits'ebetsong tse ling, pH e ka tsitsisoa ka ho kenyelletsa li-buffers ho boloka viscosity e tsitsitseng.

8. Sebelisa li-agent tse kopanyang
Maemong a mang, ho eketsoa ha li-agent tse hokahanyang li ka eketsa haholo viscosity ea HPMC. Lisebelisoa tse hokahanyang li ka theha likhokahano tsa 'mele kapa tsa lik'hemik'hale lipakeng tsa limolek'hule tsa HPMC le ho ntlafatsa tšebelisano lipakeng tsa liketane tsa limolek'hule, ka hona, li eketsa viscosity. Ka mohlala, ho li-adhesives tsa kaho, ho hokahanya ha HPMC ho ka susumetsoa ka ho eketsa palo e loketseng ea boric acid kapa li-ion tse ling tse ngata ho fumana tsamaiso e phahameng ea viscosity.

9. Taolo ea Mocheso le Mongobo
Lits'ebetsong tse sebetsang, viscosity ea li-adhesives tsa HPMC e boetse e angoa ke mocheso le mongobo o teng. Mocheso o eketsehileng ka kakaretso o fokotsa viscosity ea HPMC, ha mongobo o ntseng o eketseha o ka baka ho fetoha ha viscosity ho sekhomaretsi. Ka hona, ho boloka maemo a nepahetseng a mocheso le mongobo sebakeng sa kaho ho ka thusa ho boloka viscosity e loketseng ea sekhomaretsi sa HPMC.

10. Ho ntlafatsa maemo a polokelo
Maemo a polokelo ea likhomaretsi tsa HPMC a na le litlamorao tsa nako e telele ho viscosity. E le ho boloka botsitso ba viscosity, li-adhesive li lokela ho bolokoa sebakeng se omeletseng, se pholileng, ho qoba mocheso o phahameng le maemo a mongobo o phahameng. Ho feta moo, nako e telele ea polokelo e ka lebisa ho fokotseha ha viscosity. Ka hona, ho hlahloba kamehla viscosity ea sekhomaretsi le ho etsa liphetoho ha ho hlokahala hape ke mehato ea bohlokoa ho netefatsa boleng ba sekhomaretsi.


Nako ea poso: Sep-03-2024
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