Mokhoa oa ho qhala oa (Hydroxypropyl Methyl Cellulose)HPMC

Ho qhibiliha ha Hydroxypropyl Methylcellulose (HPMC) hangata ho kenyelletsa ho qhala phofo ea polymer ka metsing tlas'a maemo a laoloang ho etsa bonnete ba hore ho na le metsi a nepahetseng le ho qhibiliha. Mona ke mokhoa o akaretsang oa ho qhala HPMC:

Lintho Tse Hlokehang:

1. HPMC phofo
2. Metsi a silafalitsoeng kapa a senyehileng (bakeng sa liphetho tse ntle)
3. Sejana se kopanyang kapa setshelo
4. Sehlahisoa kapa lisebelisoa tse kopanyang
5. Lisebelisoa tsa ho lekanya (haeba ho hlokahala dosing e nepahetseng)

Mokhoa oa ho Fetola:

1. Lokisetsa Metsi: Lekanya palo e hlokahalang ea metsi a hloekisitsoeng kapa a hloekisitsoeng ho latela motsoako o lakatsehang oa tharollo ea HPMC. Ho bohlokoa ho sebelisa metsi a boleng bo holimo ho thibela litšila kapa litšila ho ama mokhoa oa ho qhala.
2. Chesa Metsi (Ka boikhethelo): Ha ho hlokahala, futhumatsa metsi ho mocheso o pakeng tsa 20 ° C ho isa ho 40 ° C (68 ° F ho ea ho 104 ° F) ho nolofatsa ho qhibiliha. Ho futhumatsa ho ka potlakisa hydration ea HPMC le ho ntlafatsa ho hasana ha likaroloana tsa polymer.
3. Butle-butle Eketsa Powder ea HPMC: Butle-butle eketsa phofo ea HPMC metsing ha u ntse u susumetsa ka ho tsoelang pele ho thibela ho kopanya kapa ho kopanya. Ho bohlokoa ho eketsa phofo butle-butle ho etsa bonnete ba ho hasana ho tšoanang le ho qoba ho thehoa ha maqhubu.
4. Tsoela Pele ho Tsoela Pele: Boloka ho tsosoa kapa ho ferekana ha motsoako ho fihlela phofo ea HPMC e qhalakanngoa ka ho feletseng 'me e na le metsi. Hangata sena se nka metsotso e 'maloa, ho itšetlehile ka boholo ba karoloana ea phofo ea HPMC le lebelo le susumetsang.
5. Lumella Hydration: Ka mor'a ho eketsa phofo ea HPMC, lumella motsoako hore o eme nako e lekaneng ho etsa bonnete ba hore metsi a feletseng a polymer. Sena se ka tloha ho metsotso e 30 ho isa ho lihora tse 'maloa, ho latela kereiti e itseng le boholo ba karolo ea HPMC.
6. Fetola pH (ha ho hlokahala): Ho itshetlehile ka tshebediso, o ka nna wa hloka ho lokisa pH ya tharollo ya HPMC o sebedisa ditharollo tsa asiti kapa alkali. Mohato ona o bohlokoa haholo bakeng sa lits'ebetso moo ho hlaka ha pH ho leng bohlokoa, joalo ka litlamong tsa meriana kapa tsa tlhokomelo ea motho.
7. Sefa (haeba ho hlokahala): Haeba tharollo ea HPMC e na le likaroloana tse sa tsitsang kapa li-aggregate tse sa qhibilihang, ho ka 'na ha hlokahala hore ho sefa tharollo ho sebelisa sieve e ntle ea letlooeng kapa pampiri ea ho hloekisa ho tlosa lintho tse setseng tse setseng.
8. Boloka kapa Sebelisa: Hang ha HPMC e qhibilihisitsoe ka botlalo 'me e na le metsi, tharollo e se e loketse ho sebelisoa. E ka bolokoa ka sejaneng se tiisitsoeng kapa ea sebelisoa hang-hang lits'ebetsong tse fapaneng tse kang meriana, litlolo, thepa ea kaho, kapa lihlahisoa tsa lijo.

Lintlha:

• Qoba ho sebelisa metsi a thata kapa metsi a nang le liminerale tse ngata, kaha a ka ama ts'ebetso ea ho qhibiliha le ts'ebetso ea tharollo ea HPMC.
• Nako ea ho qhibiliha le mocheso li ka 'na tsa fapana ho itšetlehile ka sehlopha se itseng, boholo ba likaroloana, le sekhahla sa viscosity ea phofo ea HPMC e sebelisitsoeng.
• Kamehla latela likhothaletso le litataiso tsa moetsi bakeng sa ho lokisa litharollo tsa HPMC, kaha limaraka tse fapaneng li ka ba le litlhoko tse ikhethileng bakeng sa ho qhaloa.