Focus on Cellulose ethers

Ho bapisa Hydroxyethyl Cellulose (HEC) le Li-Ether tse ling tsa Cellulose

Hydroxyethyl Cellulose (HEC) le tse ling tse cellulose ethers (tse kang hydroxypropyl methylcellulose (HPMC), methylcellulose (MC), hydroxypropyl cellulose (HPC) le carboxymethyl cellulose (CMC)) ke polymers multifunctional tse sebelisoang haholo indastering, kaho, meriana, lijo le letsatsi le letsatsi. liindasteri tsa lik'hemik'hale. Li-derivatives tsena tsa cellulose li entsoe ka selulose e fetolang lik'hemik'hale 'me li na le metsi a mangata a qhibilihisang, a teteaneng, a tsitsitseng le a ho etsa lifilimi.

1. Hydroxyethyl Cellulose (HEC)

1.1 Sebopeho sa Lik'hemik'hale le Thepa

Hydroxyethyl Cellulose (HEC) e entsoe ka hydroxyethylation ea selulose e nang le ethylene oxide tlas'a maemo a alkaline. Sebopeho sa motheo sa HEC ke tlamo ea ether e entsoeng ka ho nkela sebaka sa sehlopha sa hydroxyl molek'hule ea cellulose ke sehlopha sa hydroxyethyl. Sebopeho sena se fa HEC thepa e ikhethang:

Ho qhibiliha ha metsi: HEC e qhibiliha ka metsing a batang le a chesang ho etsa tharollo e hlakileng ea colloidal.

Ho teteana: HEC e na le thepa e matla ea ho tenya 'me e sebelisoa haholo lits'ebetsong tse hlokang taolo ea viscosity.
Botsitso: Tharollo ea HEC e na le botsitso bo phahameng mefuteng e fapaneng ea pH.
Biocompatibility: HEC ha e chefo, ha e tenehe ebile e na le botsoalle ho 'mele oa motho le tikoloho.
1.2 Mabaka a kopo
Lisebelisoa tsa kaho: e sebelisoa e le sekontiri le se bolokang metsi bakeng sa seretse sa samente le lihlahisoa tsa gypsum.
Liaparo le lipente: li sebelisoa e le motenya, moemeli oa ho emisa le ho tsitsisa.
Lik'hemik'hale tsa letsatsi le letsatsi: li sebelisoa e le setenya linthong tse hlokahalang tsa letsatsi le letsatsi joalo ka li-detergents le li-shampoo.
Sebaka sa meriana: se sebelisoa e le sekhomaretsi, se teteaneng le se emisang matlapa a lithethefatsi.
1.3 Melemo le go tlhoka mesola
Melemo: ho qhibiliha ha metsi hantle, botsitso ba lik'hemik'hale, ho ikamahanya le maemo ka bophara ba pH le ho se chefo.
Go tlhoka mesola: ho qhibidiha ho fokolang ho dihlapolli tse ding, mme theko e ka ba hodimo hanyane ho feta tse ding tse ding tsa cellulose ethers.
2. Papiso ea li-cellulose ethers tse ling
2.1 Hydroxypropyl methylcellulose (HPMC)
2.1.1 Sebopeho sa lik'hemik'hale le thepa
HPMC e entsoe ka selulose ka methylation le hydroxypropylation reactions. Sebopeho sa eona se na le li-substitutes tse peli tsa methoxy (-OCH3) le hydroxypropoxy (-OCH2CH (OH) CH3).
Ho qhibiliha ha metsi: HPMC e qhibiliha ka metsing a batang ho etsa tharollo e hlakileng ea colloidal; ha e na ho qhibiliha ha bobebe metsing a chesang.
Thepa e teteaneng: E ​​na le bokhoni bo botle ba ho tenya.
Gelling properties: E etsa gel ha e futhumala ebe e khutlela boemong ba eona ba pele ha e pholisitsoe.

2.1.2 Libaka tsa kopo
Thepa ea kaho: E sebelisoa e le ntho e thibelang metsi le ho boloka metsi bakeng sa lisebelisoa tse thehiloeng ho samente le tsa gypsum.
Lijo: E sebelisoa e le emulsifier le stabilizer.
Meriana: E sebelisoa e le motsoako oa li-capsules tsa meriana le matlapa.

2.1.3 Melemo le bofokoli
Melemo: Ts'ebetso e ntle ea botenya le thepa ea gelling.
Mefokolo: E khona ho mamella mocheso 'me e ka' na ea hlōleha ho sebelisa mocheso o phahameng.

2.2 Methyl cellulose (MC)

2.2.1 Sebopeho sa lik'hemik'hale le thepa
MC e fumanoa ka methylation ea selulose 'me haholo-holo e na le methoxy (-OCH3) substitutes.
Ho qhibiliha ha metsi: e qhibiliha hantle metsing a batang ho etsa tharollo e hlakileng ea colloidal.
Thickening: e na le phello e kholo ea ho teteana.
Thermal gelation: e etsa gel ha e futhumala le ho theola ha e pholile.

2.2.2 Libaka tsa kopo
Lisebelisoa tsa ho haha: tse sebelisoang e le sekontiri le se bolokang metsi bakeng sa seretse le pente.
Lijo: e sebelisoa e le emulsifier le stabilizer.

2.2.3 Melemo le bofokoli
Melemo: bokhoni bo matla ba ho tiisa, hangata bo sebelisoa ho theknoloji ea ho sebetsa ka serame.
Mefokolo: ha e na mocheso, e ke ke ea sebelisoa ka mocheso o phahameng.

2.3 Hydroxypropyl cellulose (HPC)

2.3.1 Sebopeho sa lik'hemik'hale le thepa
HPC e fumanoa ka hydroxypropyl cellulose. Sebopeho sa eona se na le hydroxypropoxy (-OCH2CH(OH)CH3).
Ho qhibiliha ha metsi: ho qhibiliha ka metsing a batang le lihlapolli tsa tlhaho.
Thickening/ Ketso ya ho kokota: tshebetso e ntle ya ho tenya.
Thepa ea ho etsa lifilimi: e etsa filimi e matla.

2.3.2 Mabala a kopo
Meriana: e sebelisoa e le lisebelisoa tsa ho roala le lisebelisoa tsa letlapa bakeng sa lithethefatsi.
Lijo: e sebelisoa e le motenya le stabilizer.

2.3.3 Melemo le bofokoli
Melemo: ho qhibiliha ha multi-solvent le thepa e babatsehang ea ho etsa lifilimi.
Go tlhoka mesola: theko e phahameng.

2.4 Carboxymethyl cellulose (CMC)

2.4.1 Sebopeho sa lik'hemik'hale le litšobotsi
CMC e entsoe ka ho arabela selulose ka chloroacetic acid, 'me e na le sehlopha sa carboxymethyl (-CH2COOH) ka sebopeho sa eona.
Ho qhibiliha ha metsi: ho qhibiliha ka metsing a batang le metsing a chesang.
Thepa e teteaneng: phello e kholo ea ho tenya.
Ionicity: ke ea anionic cellulose ether.

2.4.2 Mabala a kopo
Lijo: e sebelisoa e le motenya le stabilizer.
Lik'hemik'hale tsa letsatsi le letsatsi: tse sebelisoang e le motenya bakeng sa sesepa.
Ho etsa lipampiri: e sebelisoa e le tlatsetso bakeng sa ho roala pampiri.

2.4.3 Melemo le bofokoli
Melemo: botenya bo botle le libaka tse pharaletseng tsa ts'ebeliso.
Mefokolo: ho nahanela electrolyte, ion tharollo e ka ama ts'ebetso.

3. Papiso e felletseng

3.1 Ts'ebetso e teteaneng

HEC le HPMC li na le ts'ebetso e ts'oanang ea ho tenya 'me ka bobeli li na le phello e ntle ea ho teteana. Leha ho le joalo, HEC e na le ho qhibiliha ha metsi ho betere mme e loketse lits'ebetso tse hlokang pepeneneng le ho halefa hanyane. HPMC e na le thuso ho feta lits'ebetsong tse hlokang ho futhumatsa ho gel ka lebaka la thepa ea eona ea thermogel.

3.2 Ho qhibiliha ha metsi

HEC le CMC ka bobeli li ka qhibiliha metsing a batang le a chesang, ha HPMC le MC li qhibiliha haholo metsing a batang. HPC e ratoa ha ho hlokahala hore ho sebetsane le multi-solvent.

3.3 Theko le mefuta ea ts'ebeliso

HEC hangata e theko e tlase ebile e sebelisoa haholo. Leha HPC e na le ts'ebetso e ntle haholo, hangata e sebelisoa lits'ebetsong tse batloang haholo ka lebaka la theko ea eona e phahameng. CMC e na le sebaka lits'ebetsong tse ngata tse theko e tlase ka theko e tlase le ts'ebetso e ntle.

Hydroxyethyl cellulose (HEC) e fetohile e 'ngoe ea li-cellulose ethers tse sebelisoang ka ho fetisisa ka lebaka la ho qhibiliha ha eona ha metsi, botsitso le matla a ho teteaneng. Ha ho bapisoa le li-ethers tse ling tsa cellulose, HEC e na le melemo e itseng ea ho qhibiliha ha metsi le botsitso ba lik'hemik'hale, 'me e loketse likopo tse hlokang tharollo e hlakileng le ho feto-fetoha ha pH ka bophara. HPMC e ipabola libakeng tse itseng tse itseng ka lebaka la ho teteana ha eona le thepa ea ho chesoa ha mocheso, ha HPC le CMC li le maemong a bohlokoa mafapheng a tsona a fapaneng a kopo ka lebaka la thepa ea tsona ea ho etsa lifilimi le melemo ea litšenyehelo. Ho latela litlhoko tse ikhethileng tsa ts'ebeliso, ho khetha ether e nepahetseng ea cellulose ho ka ntlafatsa ts'ebetso ea sehlahisoa le ho boloka litšenyehelo.


Nako ea poso: Jul-10-2024
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