Waa maxay nooca polymer-ka HPMC?

HPMC, ama hydroxypropyl methylcellulose, waa nooc ka mid ah polymer-ku-saleysan cellulose kaas oo si weyn loogu isticmaalo warshadaha dawooyinka, cuntada, iyo daryeelka shakhsi ahaaneed. Cellulose waa polymer dabiici ah oo laga helo dhirta waana isku dhafka ugu badan ee dabiiciga ah ee dhulka. Waa polymer toosan oo ka samaysan monomers gulukoos oo ay ku xidhan yihiin β(1→4) glycosidic bonds.

HPMC waxa soo saara iyada oo si kiimiko ah wax ka beddeleysa cellulose oo leh methyl ama kooxaha hydroxypropyl midkood. Wax ka beddelkan waxa lagu samayn karaa iyada oo la falcelinayo cellulose leh reagents ku habboon iyadoo ay jirto kiciye asiidh ah. Falcelinta u dhaxaysa cellulose iyo methyl chloride ama methyl bromide waxay dhalisaa methylcellulose, halka falcelinta u dhaxaysa cellulose iyo propylene oxide ay dhaliso hydroxypropyl cellulose. HPMC waxa la soo saaray iyadoo la isku daray labadan falcelis si loo baro kooxaha methyl iyo hydroxypropyl labadaba laf dhabarta cellulose.

Polymer-ka soo baxay wuxuu leeyahay qaab dhismeed kakan oo kala duwanaan kara iyadoo ku xiran heerka beddelka (DS) ee kooxaha methyl iyo hydroxypropyl. DS waxa ay tilmaamaysaa celceliska tirada kooxaha hydroxyl ee la beddelay unugga anhydroglucose ee ku jira laf dhabarta cellulose. Caadi ahaan, HPMC waxay leedahay DS oo ah 1.2 ilaa 2.5 ee kooxaha methyl iyo 0.1 ilaa 0.3 ee kooxaha hydroxypropyl. Qaab dhismeedka HPMC waxaa sii murgay xaqiiqda ah in kooxaha methyl iyo hydroxypropyl si aan kala sooc lahayn loogu qaybin karo lafta dhabarka cellulose, taasoo keentay in polymer a heterogeneous ah oo leh noocyo kala duwan oo hanti ah.

HPMC waa polymer-ka biyaha ku milma taasoo samaysa walax jel oo kale ah marka la fuuqeeyo. Tilmaamaha gelation-ka ee HPMC waxay ku xiran yihiin dhowr arrimood, oo ay ku jiraan DS, miisaanka kelli, iyo xoogga saarida polymerka. Guud ahaan, HPMC waxay samaysaa jel xasiloon oo aad u sarreeya oo leh qiyamka DS sare. Intaa waxaa dheer, sifooyinka gelation ee HPMC waxaa saameyn ku yeelan kara pH, xoogga ionic, iyo heerkulka xalka.

Sifooyinka gaarka ah ee HPMC waxay ka dhigaan shay qiimo leh codsiyo badan. Warshadaha dawooyinka, HPMC waxa loo isticmaalaa sidii xidhe, kala daadsan, iyo wakiilka filim samaynta ee kiniiniyada iyo kaabsal. Waxa kale oo loo isticmaali karaa in wax laga beddelo heerka siidaynta daawooyinka ee foomka qiyaasta. Warshadaha cuntada, HPMC waxa loo isticmaalaa sidii dhumuc, xasiliye, iyo emulsifier ahaan. Inta badan waxaa loo adeegsadaa cuntooyinka dufanku ku yar yahay ama kaloriyada yar-yar si loogu ekaysiiyo nuxurka iyo dareenka afka ee cuntooyinka dufanka badan. Warshadaha daryeelka shakhsi ahaaneed, HPMC waxaa loo isticmaalaa dhumuc ahaan, wakiilka filim samaynta, iyo emulsifier ee shaambooyinka, looshannada, iyo alaabada kale.

Gebagebadii, HPMC waa polymer-ku-saleysan cellulose kaas oo ay soo saarto si kiimiko ah cellulose wax looga beddelo kooxaha methyl iyo hydroxypropyl. polymerka soo baxay waa biyo-milmi leh oo leh qaab dhismeed adag oo kala duwanaan kara iyadoo ku xiran heerka beddelka iyo qaybinta kooxaha methyl iyo hydroxypropyl. HPMC waa polymer-ka badan oo leh codsiyo badan oo ku saabsan daawooyinka, cuntada, iyo warshadaha daryeelka shakhsi ahaaneed.