HPMC, ama Hydroxypropyl Methylcellulose, waa polymer synthetic oo si weyn loogu isticmaalo farmashiyaha, cuntada, qurxinta iyo goobaha dhismaha. Waxay leedahay sifooyin aad u wanaagsan oo badan sida milanka, xasilloonida, hufnaanta iyo sameynta filimada sida dhumuc, koollo, filim hore, wakiilka sugidda iyo kolloid ilaalin ah.
Marka la eego viscosity-ka HPMC, waa fikrad aad u adag sababtoo ah viscosity waxaa saameeya arrimo badan, sida xoogga saarista, miisaanka kelli, dareeraha, heerkulka iyo heerka xiirid.
Xiriirka ka dhexeeya miisaanka kelli iyo viscosity: Miisaanka molecular ee HPMC waa mid ka mid ah arrimaha muhiimka ah ee go'aamiya viscositykeeda. Guud ahaan marka loo hadlo, mar kasta oo uu sareeyo miisaanka molecular, ayaa sare u kacaya viscosity ee HPMC. Sidaa darteed, soosaarayaashu waxay inta badan bixiyaan alaabada HPMC miisaanyo unugyo kala duwan si ay u daboolaan baahiyaha warshado kala duwan. Miisaanka molecular waxaa badanaa loo muujiyaa sida qiimaha K (sida K100, K200, iwm.). Marka uu bato qiimaha K, waa uu sarreeyaa viscosity-ku.
Saamaynta feejignaanta: viscosity ee xalka HPMC ee biyaha wuxuu kordhiyaa kororka feejignaanta. Tusaale ahaan, 1% fiirsashada xalka HPMC waxa laga yaabaa inuu yeesho viscosity dhawr jeer ka sarreeya kan 0.5% xalka. Tani waxay u ogolaaneysaa viscosity ee xalka in la xakameeyo iyadoo la hagaajinayo diiradda HPMC ee codsiga.
Saamaynta dareeraha: HPMC waxa lagu milmi karaa biyo ama dareerayaasha organic, laakiin dareerayaasha kala duwani waxay saameeyaan viscosity. Guud ahaan, HPMC waxay leedahay milmayn wanaagsan oo biyaha ah iyo mawqifka xalku waa sarreeyaa, halka viscosity ee dareerayaasha organic ay ku kala duwan yihiin iyadoo ku xidhan polarity ee dareeraha iyo heerka beddelka ee HPMC.
Saamaynta heerkulka: Viscosity ee xalka HPMC ayaa isbeddela heerkulka. Guud ahaan, viscosity ee xal HPMC hoos u marka heerkulku kordho. Tani waa sababta oo ah kororka heerkulku wuxuu keenaa dhaq-dhaqaaq molecular oo degdeg ah iyo korodhka dareeraha xalka, kaas oo yareynaya viscosity.
Saamaynta heerka xiirid: Xalka HPMC waa dareere aan Newtonian ahayn, oo viscositykiisu wuxuu isku beddelaa heerka dhogorta. Tani waxay ka dhigan tahay inta lagu jiro walaaqaya ama bamgareynta, viscosity-ku wuxuu isbeddelaa xoojinta hawlgalka. Guud ahaan, xalalka HPMC waxa uu muujiyaa sifooyinka khafiifinta xiirta, taas oo ah, viscosity-ku hoos ayuu u dhacaa marka la eego heerarka sare ee xiiridda.
Heerarka HPMC iyo qeexitaannada: Darajooyinka kala duwan ee alaabta HPMC waxay sidoo kale leeyihiin farqi weyn oo ku saabsan viscosity. Tusaale ahaan, sheyga HPMC ee heerka viscosity-ga hoose waxa laga yaabaa inuu lahaan karo muuqalka 20-100mPas oo ah 2% fiirsi, halka darajada viscosity sare ee sheyga HPMC uu yeelan karo mawjadaha ilaa 10,000-200,000 mPas isla uruursi la mid ah. Sidaa darteed, marka la dooranayo HPMC, waxaa muhiim ah in la doorto darajada viscosity ee ku habboon iyadoo lagu salaynayo shuruudaha codsiga gaarka ah.
Hababka tijaabada caadiga ah: Viscosity ee HPMC waxaa badanaa lagu cabbiraa viscometer ama rheometer. Hababka baaritaanka caadiga ah waxaa ka mid ah viscometer wareeg ah iyo viscometer capillary. Xaaladaha tijaabada sida heerkulka, xoogga saarista, nooca dareeraha, iwm. waxay saameyn weyn ku yeelan karaan natiijooyinka, markaa cabbirradan waxay u baahan yihiin in si adag loo xakameeyo inta lagu jiro baaritaanka.
Viscosity ee HPMC waa halbeeg adag oo ay saameeyeen arrimo badan, iyo hagaajintiisa ayaa ka dhigaysa in si ballaaran loo isticmaalo codsiyada kala duwan. Haddi ay ahaan lahayd cuntada, dawooyinka, agabka dhismaha ama warshadaha isqurxinta, fahanka iyo xakamaynta viscosity ee HPMC waa mid ka mid ah qodobada muhiimka ah ee lagu hubinayo tayada iyo waxqabadka badeecada.
Waqtiga boostada: Agoosto-28-2024