Cudbi la safeeyey—furid — alkalization — etherification — dhexdhexaad ka noqosho — kala saarid — dhaqid — kala go`an — qallajin — burburin — baakad — dhammaatay furitaanka alaabta HPMC: Cudbiga la safeeyey ayaa la furay si looga saaro birta ka dibna la jajabiyo. Cudbiga la safeeyey ee la miiray waa qaab budo ah, oo leh xajmi qaybeed 80 mesh ah iyo gudbinta 100%. Haddii kale, way fududahay in la isku duubo inta lagu jiro habka falcelinta oo la yareeyo waxtarka etherification.
Alkalization: Ku dar suufka la safeeyey ee budada ah ka dib furitaanka suufka dareeraha aan firfircoonayn, oo ku dhaqaaji alkali iyo biyo jilicsan si aad u bararto suufka la safeeyey si loo fududeeyo dhexgalka molecules wakiilka etherification iyo hagaajinta isku midka ah ee falcelinta etherification. Alkalization-ka loo isticmaalo alkalization waa bir hydroxide ama alkali organic. Qadarka alkali ee lagu daray (cusub, isla hoos) waa 0.1-0.6 jeer ka badan suufka la safeeyey, qadarka biyaha jilicsan ee lagu daray 0.3-1.0 jeer ka badan suufka la safeeyey; dareeraha qallafsan waa isku dhafka khamriga iyo hydrocarbon, iyo qadarka dareeraha dareeraha ah ee lagu daray 0.3-1.0 jeer ka badan suufka la safeeyey. 7-15 jeer oo ka mid ah: dareeraha qallafsan wuxuu kaloo noqon karaa aalkolo leh 3-5 atamka kaarboon (sida khamriga, propanol), acetone. Waxa kale oo ay noqon kartaa hydrocarbons aliphatic iyo hydrocarbons udgoon; heerkulka waa in lagu xakameeyo 0-35 ° C inta lagu jiro alkalization; waqtiga alkalization waa ilaa 1hr. Hagaajinta heerkulka iyo waqtiga waxaa lagu go'aamin karaa iyadoo loo eegayo shuruudaha alaabta iyo alaabta.
Etherification: Daawaynta alkalization ka dib, xaaladaha faakuumka, wakiilka etherification ayaa lagu daraa etherification, iyo wakiilka etherification waa propylene oxide. Si loo yareeyo isticmaalka wakiilka etherification, inta lagu guda jiro habka etherification, wakiilka etherification ayaa lagu daraa laba jeer, qadarka ugu horreeya ee lagu daro waa 1-3.5 jeer ka badan suufka la safeeyey, wadarta qadarka labada lagu daray waa 1.5 -4 jeer ka badan suufka la safeeyey. waqtiyo. Ka dib marka lagu daro wakiilka etherifying markii ugu horeysay, walaaq at ≤30 ° C 45min-90min, ka dibna kor u heerkulka ilaa 50-100 ° C ee etherification 1-5h, ka dibna qabooji ilaa ≤30 ° C , mar labaad in lagu daro walaaqaya etherification, waqtiga walaaqaya waa 30-120min, ka dibna kuleyl si? ? ? Samee etherification, wakhtigu waa 1-4 saac, wakhtigan, suufka la safeeyey ayaa si buuxda ula falgala wakiilka etherification si uu u dhaliyo HYDROXYPROPYL METHYLCELLULLOSE HPMC.
Burburinta iyo baakaynta: burburinta iyo shaandhaynta badeecada la qalajiyey ee ikhtiraacida hadda jirta, cabbirka qayb ka mid ah sheyga HPMC ee ikhtiraacida iyo shaandhaynta hadda waa 40 mesh iyo gudbinta waa 10096, ama marka loo eego baahida isticmaale. Kadibna xirxiro HPMC.
Waqtiga boostada: Nov-24-2022