Siideynta joogtada ah iyo diyaarinta sii deynta la kontoroolo: Ether-ka Cellulose sida HPMC (hydroxypropyl methylcellulose) ayaa inta badan loo adeegsadaa agabka qalfoofka hydrogel ee diyaarinta sii deynta joogtada ah. Waxay xakameyn kartaa heerka sii deynta daroogada ee jirka bini'aadamka si loo gaaro saameyn daweyn ah. Heerka viscosity-hoose HPMC waxa loo isticmaali karaa sidii koollo ahaan, dhumuc yar iyo wakiilka laalista, halka darajada sare-viskosity HPMC loo isticmaalo in lagu diyaariyo walxo isku qasan kaniiniyada sii daayo waarta, kaabsoosha sii-daynta joogtada ah, iyo hydrophilic gel qalfoof kiniiniyada sii-daynta joogtada ah.
Dahaarka samaynta filimada: HPMC waxay leedahay sifooyin samaynta filimada oo wanaagsan, filimka la sameeyayna waa labbis, hufan, adag, oo aan fududayn in loo hoggaansamo. Waxay wanaajin kartaa xasilloonida daawada waxayna ka hortagtaa midabka. Isku darka guud ee HPMC waa 2% ilaa 10%.
Kaabayaasha dawooyinka: Cellulose ethers waxay door muhiim ah ka ciyaaraan diyaarinta qaabaynta sida daawooyinka dawooyinka, sida pellets-sii-daynta joogtada ah, diyaargarowga sii-deynta qalfoofka, diyaarinta sii-deynta joogtada ah ee dahaarka leh, kaabsoosha-sii-daynta joogtada ah, sii-deynta joogtada ah-filimka daawada-soo-celinta. diyaarinta sii deynta iyo diyaargarowga sii deynta dareeraha joogtada ah.
Microcrystalline Cellulose (MCC): MCC waa nooc ka mid ah cellulose oo si weyn loogu isticmaalo warshadaha dawooyinka, gaar ahaan isku-buufinta tooska ah iyo hababka qallafsanaanta qallalan sida rullaluistemadka si loogu diyaariyo kaniiniyada la cufan ama granules.
Bioadhesives: Cellulose ethers, gaar ahaan nonionic iyo anionic derivatives ether sida EC (ethylcellulose), HEC (hydroxyethylcellulose), HPC (hydroxypropylcellulose), MC (methylcellulose), CMC (carboxymethylcellulose) ama HPMC (hydroxypropyl) waa biosimethyla la isticmaalo. Polymers-yadan waxa loo isticmaali karaa afka, indhaha, siilka iyo bioadhesives-ka transdermal, kaligood ama lagu daro polymers kale.
Dhuxusha iyo xasiliyayaasha: Ka-soo-saaryada cellulose ayaa si weyn loo isticmaalaa si loo adkeeyo xalalka daroogada iyo nidaamyada kala firdhiso sida emulsions iyo ganaaxyo. Polymers-yadani waxay kordhin karaan viscosity ee xalalka daroogada aan biyo-biyoodka ahayn sida xalalka daahan organic-ku salaysan. Kordhinta viscosity ee xalalka daroogada waxay hagaajin kartaa bioavailability ee diyaarinta jirka iyo xuubka.
Buuxiyeyaasha: Cellulose iyo waxyaabaha ka soo baxa ayaa caadi ahaan loo isticmaalaa buuxinta foomamka qiyaasta adag sida kiniiniyada iyo kaabsalka. Waxay la jaan qaadayaan inta badan waxyaabaha kale ee waxtarka leh, farmashiil ahaan aan firfircoonayn, oo aan dheefshiidin enzymes-ka caloosha iyo mindhicirka bini'aadamka.
Binders: Ether-ka Cellulose waxaa loo isticmaalaa sida xidheyaal inta lagu jiro habka granulation si ay u caawiyaan samaynta granules iyo ilaalinta daacadnimadooda.
Kaabsoosha dhirta: Ether-ka Cellulose waxa sidoo kale loo isticmaalaa in lagu sameeyo kaabsal dhirta, beddelka deegaanka u saaxiibka ah kaabsoosha-dhaqameedka laga keeno xayawaanka.
Nidaamyada gudbinta maandooriyaha: Ether-ka Cellulose waxaa loo isticmaali karaa in lagu horumariyo hababka kala duwan ee gudbinta daroogada, oo ay ku jiraan siidaynta la kantaroolo iyo hababka dib-u-daaminta, iyo sidoo kale nidaamyada goobta-gaarka ah ama waqti-gaar ah ee daroogada.
Codsiga ethers-ka cellulose-ka ee warshadaha dawooyinka ayaa sii kordhaya, iyo horumarinta foomamka qiyaasta cusub iyo waxyaabaha cusub, baaxadda baahida suuqa ayaa la filayaa inay sii korodho.
Waqtiga boostada: Oct-31-2024