Hydroxypropylmethylcellulose (HPMC) waa polymer-ka shaqeeya oo badan oo laga soo qaatay cellulose dabiiciga ah. Waxaa caadi ahaan loo adeegsadaa warshado kala duwan, oo ay ku jiraan dawooyinka, cuntada, dhismaha iyo waxyaabaha la isku qurxiyo. Soo saarista HPMC waxay ku lug leedahay noocyo kala duwan oo alaab cayriin ah iyo habraac dhowr tallaabo ah.
Cellulose:
Isha: Waxyaabaha ugu muhiimsan ee ceeriin ee HPMC waa cellulose, karbohaydrayt adag oo laga helo gidaarada unugyada dhirta. Ilaha ugu caansan ee cellulose ee wax soo saarka HPMC waa saxarka alwaax, laakiin ilo kale sida suufka suufka ayaa sidoo kale la isticmaali karaa.
Diyaarinta: Cellulose waxaa sida caadiga ah lagu daaweeyaa in laga saaro wasakhda kadibna waxaa lagu farsameeyaa qaab ku haboon in wax laga beddelo.
Saldhig:
Nooca: Sodium hydroxide (NaOH) ama potassium hydroxide (KOH) ayaa inta badan loo isticmaalaa saldhigga inta lagu jiro marxaladaha hore ee wax soo saarka HPMC.
Shaqada: Alkali waxaa loo isticmaalaa in lagu daweeyo cellulose, taasoo keenta inay bararto oo burburiso dhismaheeda. Nidaamkan, oo loo yaqaan 'alkalisation', wuxuu u diyaariyaa cellulose-ka falcelin dheeraad ah.
Wakiilka etherifying Alkali:
Wakiilka Hydroxypropylating: Propylene oxide waxaa badanaa loo isticmaalaa in lagu soo bandhigo kooxaha hydroxypropyl ee laf dhabarta cellulose. Talaabadani waxay siisaa milanka iyo guryaha kale ee la doonayo cellulose.
Methylating agents: Methyl chloride ama dimethyl sulfate ayaa inta badan loo isticmaalaa in lagu soo bandhigo kooxaha methyl qaab dhismeedka cellulose, si kor loogu qaado hantideeda guud.
Wakiilka Methylating:
Methanol: Methanol waxaa caadi ahaan loo isticmaalaa sida dareeraha iyo falcelinta hababka methylation. Waxay gacan ka geysataa soo bandhigida kooxaha methyl ee silsiladaha cellulose.
Wakiilka Hydroxypropylating:
Propylene oxide: Waa alaabta ceeriin ee muhiimka ah ee lagu soo bandhigo kooxaha hydroxypropyl cellulose. Falcelinta u dhaxaysa propylene oxide iyo cellulose waxay ku dhacdaa xaalado la xakameeyey.
kicin:
Acid Catalyst: Kataliye asiidh ah, sida sulfuric acid, ayaa loo isticmaalaa si kor loogu qaado falcelinta etherification. Waxay gacan ka geystaan xakamaynta heerarka falcelinta iyo sifooyinka alaabta.
Walxaha
Biyaha: Biyaha waxaa badanaa loo isticmaalaa sida dareere marxaladaha kala duwan ee habka wax soo saarka. Waa lagama maarmaan in la kala diro fal-celiyeyaasha iyo kor u qaadista falcelinta u dhexeeya cellulose iyo wakiilada etherifying.
Dhexdhexaadiye:
Sodium hydroxide (NaOH) ama potassium hydroxide (KOH): waxaa loo isticmaalaa in laga takhaluso kicinta aashitada iyo hagaajinta pH inta lagu jiro isku-dhafka.
nadiifiye:
Caawinta shaandhaynta: Qalabyo kala duwan ayaa loo isticmaali karaa in laga saaro wasakhda iyo alaabada aan la rabin ee isku darka falcelinta.
Saabuunta: Ku maydhashada biyaha ama dareerayaasha kale waxay caawisaa in laga saaro kiimikooyinka haraaga ah iyo wasakhda alaabta u dambaysa.
Qalajiyaha:
Hawo ama foorno qallajin: Ka dib marka la nadiifiyo, alaabtu waxay noqon kartaa hawo ama foorno la qalajiyo si looga saaro dareeraha iyo qoyaanka haraaga ah.
Wakiilka ilaalinta tayada
Reagents Analytical: Reagents kala duwan ayaa loo isticmaalaa ujeedooyinka ilaalinta tayada si loo hubiyo in alaabta HPMC ay buuxiyaan waxqabadka iyo qeexida loo baahan yahay.
Soo saarista hydroxypropyl methylcellulose waxay ku lug leedahay wax ka beddelka cellulose iyada oo loo marayo falcelin kiimiko oo taxane ah. Qalabka ceeriin waxaa ka mid ah cellulose, alkali, wakiilka etherifying, kicinta, dareeraha, wakiilka dhexdhexaadinta, wakiilka nadiifinta iyo qalajiyaha, kuwaas oo door muhiim ah ka ciyaara habka isku-dhafka. Xaaladaha gaarka ah iyo reagen-yaasha la isticmaalay way kala duwanaan karaan iyadoo ku xidhan guryaha la doonayo iyo codsiga ugu dambeeya ee hydroxypropyl methylcellulose.
Waqtiga boostada: Dec-21-2023