Ethylcellulose waa nooc ka mid ah cellulose, oo ah polymer dabiici ah oo ka kooban unugyo gulukoos. Waxa lagu soo kordhiyey iyada oo ka falcelinaysa cellulose leh ethyl chloride ama ethylene oxide, iyada oo soo saarta unugyo cellulose qayb ahaan beddelay. Ethylcellulose waxay leedahay sifooyin kiimiko oo kala duwan oo ka dhigaya mid faa'iido u leh codsiyada warshadaha iyo daawooyinka kala duwan.
Qaab-dhismeedka Molecular:
Ethylcellulose waxay haysaa qaab dhismeedka aasaasiga ah ee cellulose, oo ka kooban unugyo gulukoos oo soo noqnoqda oo isku xidhan β-1,4-glycosidic bonds.
Beddelka Ethyl wuxuu ugu horreyn ku dhacaa kooxaha hydroxyl ee laf-dhabarka cellulose, taasoo keentay heerar kala duwan oo beddel ah (DS) oo tilmaamaya celceliska tirada kooxaha ethyl ee unugga gulukoosta.
Heerka beddelku wuxuu saameeyaa sifooyinka ethylcellulose, oo ay ku jiraan solubility, viscosity, iyo kartida samaynta filimada.
Xalka:
Sababtoo ah dabeecadda hydrophobic ee kooxda ethyl, ethylcellulose waa mid aan lagu milmi karin biyaha.
Waxay soo bandhigtaa milmiyeyaal kala duwan oo dabiici ah, oo ay ku jiraan aalkolada, ketones, esters, iyo hydrocarbons koloriin leh.
Solubility wuxuu kordhiyaa iyadoo la dhimayo miisaanka kelli iyo heerka sii kordhaya ee ethoxylation.
Guryaha sameynta filimada:
Ethylcellulose waxay caan ku tahay awoodeeda filim samaynta, taas oo ka dhigaysa mid qiimo leh soo saarista dahaarka, filimada, iyo hababka dawooyinka ee la xakameeyey.
Awoodda ethylcellulose si ay u milmaan noocyo kala duwan oo dareere organic ah waxay kor u qaaddaa sameynta filimka, iyada oo uumiga xiga ee dareeraha uu ka tago filim isku mid ah.
Falcelinta:
Ethylcellulose waxay muujisaa falcelis yar marka loo eego xaaladaha caadiga ah. Si kastaba ha ahaatee, waxaa kiimiko ahaan wax looga beddeli karaa falcelinta sida etherification, esterification, iyo isku-tallaabta.
Dareen-celinta etherification waxay ku lug leedahay soo bandhigida beddelaadyo dheeraad ah oo ku saabsan laf-dhabarka cellulose, taas oo beddeleysa sifooyinka.
Esterification waxay ku dhici kartaa iyada oo ka falcelinaysa ethylcellulose leh asiidh-carboxylic ama chlorides acid, soo saarista esters cellulose leh milanka beddelan iyo sifooyin kale.
Dareen-celinta isku-xiran ayaa la bilaabi karaa si loo hagaajiyo xoogga farsamada iyo xasilloonida kulaylka ee xuubabka ethyl cellulose.
Waxqabadka kulaylka:
Ethylcellulose waxay muujisaa xasilloonida kulaylka gudaha heerkul gaar ah, kaas oo ka baxsan burburku dhaco.
Nabaad-guurka kulaylku wuxuu caadi ahaan bilaabmaa qiyaastii 200-250 ° C, taas oo ku xidhan arrimo ay ka mid yihiin heerka beddelka iyo joogitaanka balaastikada ama waxyaabaha lagu daro.
Falanqaynta Thermogravimetric (TGA) iyo kalorimetry iskaanka kala duwan (DSC) ayaa inta badan loo isticmaalaa farsamooyin lagu garto habdhaqanka kulaylka ee ethylcellulose iyo isku darka.
waafaqid:
Ethylcellulose waxay ku habboon tahay noocyo kala duwan oo polymers ah, balaastiigyada iyo waxyaabaha lagu daro, taas oo ka dhigaysa mid ku habboon in lagu daro walxaha kale si loo gaaro sifooyinka la rabo.
Waxyaalaha lagu daro caagagga sida polyetylen glycol (PEG) iyo triethyl citrate, kuwaas oo kor u qaadaya dabacsanaanta iyo sifooyinka filimada.
Waafaqsanaanta maaddooyinka dawooyinka firfircoon (APIs) ayaa muhiim u ah samaynta foomamka qiyaasta daawada sida kiniinnada sii-daynta dheeradka ah iyo balastarka transdermal.
Waxqabadka caqabada:
Filimada Ethylcellulose waxay soo bandhigaan sifooyin aad u fiican oo ka hortagaya qoyaanka, gaaska iyo uumiga organic.
Qalabkan xannibaadaha ah ayaa ka dhigaya ethylcellulose ku habboon codsiyada baakadaha halkaas oo ka ilaalinta arrimaha deegaanka ay muhiim u tahay ilaalinta sharafta alaabta iyo nolosha shelf.
Astaamaha rheological:
Viscosity ee xalalka ethylcellulose waxay kuxirantahay arrimo ay ka mid yihiin xoojinta polymer, heerka beddelka, iyo nooca dareeraha.
Xalalka Ethylcellulose waxay inta badan muujiyaan dabeecadda pseudoplastic, taasoo la micno ah in maw-jireenkoodu hoos u dhaco iyadoo la kordhinayo heerka dhogorta.
Daraasadaha rheological ayaa muhiim u ah in la fahmo sifooyinka socodka ee xalalka ethylcellulose inta lagu jiro codsiga iyo codsiyada daahan.
Ethylcellulose waa polymer isku dhafan oo leh noocyo kala duwan oo kiimiko ah oo gacan ka geysta faa'iidooyinkeeda noocyada kala duwan ee warshadaha iyo daawooyinka. Miisaankeeda, kartida samaynta filimka, falcelinta, xasiloonida kulaylka, iswaafajinta, guryaha xannibaadda iyo rheology waxay ka dhigtaa walxo qiimo leh oo loogu talagalay dahaarka, filimada, hababka sii-deynta la xakameeyey iyo xalalka baakadaha. Cilmi-baaris dheeraad ah iyo horumarinta berrinkii soosaarayaasha cellulose waxay sii wadaan inay ballaariyaan codsiyada iyo kartida ethylcellulose ee dhinacyo kala duwan.
Waqtiga boostada: Febraayo-18-2024