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Saddex siyaabood oo lagu garto tayada hydroxypropyl methylcellulose

Hydroxypropyl methylcellulose waa polymer caan ah oo biyo-milmi kara kaas oo sameeya xal cad oo deggan biyaha waxaana si weyn loogu isticmaalaa warshadaha dawooyinka, cuntada iyo warshadaha dhismaha. Waa walxo cayriin ah oo aan-ionic cellulose-ku-salaysan oo wanaajisa isku-xidhka iyo isku-xidhnaanta alaabta ugu dambeysa. Si loo hubiyo waxqabadka tayada sare leh ee hydroxypropyl methylcellulose, alaabtu waxay u baahan tahay in la tijaabiyo oo la aqoonsado kahor isticmaalka. Maqaalkan, waxaan ka wada hadli doonaa saddex siyaabood oo la isku halleyn karo oo lagu sheegi karo tayada hydroxypropyl methylcellulose.

1. Tijaabada viscosity

Viscosity of hydroxypropyl methylcellulose waa halbeeg muhiim ah si loo go'aamiyo tayadiisa. Viscosity waa caabbinta dareere qulqulaya waxaana lagu cabbiraa centipoise (cps) ama mPa.s. Viscosity ee hydroxypropyl methylcellulose way kala duwan tahay iyadoo loo eegayo miisaankeeda kelli iyo heerka beddelka. Heerka sare ee beddelka, ayaa hoos u dhigaya viscosity ee alaabta.

Si loo tijaabiyo viscosity of hydroxypropyl methylcellulose, milaan qadar yar oo ka mid ah alaabta biyaha oo isticmaal viscometer si aad u cabbirto viscosity ee xalka. Viscosity ee xalku waa inuu ku dhex jiraa xadka lagu taliyay ee uu bixiyay alaab-qeybiyaha. Alaabada hydroxypropyl methylcellulose oo tayadeedu wanaagsan tahay waa inay lahaataa viscosity joogto ah, taasoo tilmaan u ah nadiifnimada iyo cabbirka walxaha lebbiska ah.

2. Imtixaanka beddelka

Heerka beddelka waxa loola jeedaa saamiga tirada kooxaha hydroxyl ee cellulose oo ay beddeleen hydroxypropyl ama kooxaha methyl. Heerka beddelku waa tusaha daahirsanaanta alaabta, mar kasta oo ay sarrayso heerka beddelka, waa ka saafiga ah alaabta. Alaabooyinka hydroxypropyl methylcellulose tayada sare leh waa inay lahaadaan heer sare oo beddel ah.

Si loo tijaabiyo heerka beddelka, titration ayaa lagu sameeyaa sodium hydroxide iyo hydrochloric acid. Go'aami xaddiga sodium hydroxide ee loo baahan yahay si loo baabi'iyo hydroxypropyl methylcellulose oo xisaabi heerka beddelka adoo isticmaalaya qaacidada soo socota:

Darajada Beddelka = ([Mugga NaOH] x [Molarity of NaOH] x 162) / ([Miisaanka Hydroxypropyl Methyl Cellulose] x 3)

Heerka beddelku waa inuu ku jiraa xadka lagu taliyay ee uu bixiyo alaab-qeybiyaha. Heerka beddelka alaabada hydroxypropyl methylcellulose tayada sare leh waa inay ku jirtaa xadka lagu taliyay.

3. Tijaabada xalalka

Solubility hydroxypropyl methylcellulose waa halbeeg kale oo muhiim ah oo lagu go'aaminayo tayadiisa. Alaabta waa in ay si fudud ugu milmaan biyaha oo aysan samayn burooyin ama jeel. Alaabooyinka hydroxypropyl methylcellulose tayada sare leh waa inay si dhakhso ah oo siman u milaan.

Si aad u samayso tijaabada milanka, milaan qadar yar oo badeecad ah oo biyo ah oo walaaq xalka ilaa si buuxda u milmo. Xalku waa inuu noqdaa mid cad oo ka nadiif ah buro ama jeel. Haddii alaabtu aysan si fudud u milmin ama ay samaysato burooyin ama jeel, waxay noqon kartaa calaamad tayadeedu liidato.

Gabagabadii, hydroxypropyl methylcellulose waa walxo ceeriin ah oo qiimo leh oo loo isticmaalo warshado kala duwan. Si loo hubiyo tayada sare ee alaabta, viscosity, beddelka iyo tijaabooyinka milanka ayaa la sameeyaa. Tijaabooyinku waxay kaa caawin doonaan inaad si cad u fahamto sifooyinka alaabta iyo inay caawiyaan kala soocidda tayada. Hydroxypropyl methylcellulose oo tayadiisu sareyso waxay leedahay viscosity joogto ah, heer sare oo beddelaad ah, waxayna si degdeg ah oo isku mid ah ugu milmaan biyaha.

Dufanka Dahaarka ee HPMC (1)


Waqtiga boostada: Jul-11-2023
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