Daraasad ku saabsan habdhaqanka rheological ee konjac glucomannan iyo nidaamka isku dhafka hydroxypropyl methylcellulose

Nidaamka isku dhafka ah ee konjac glucomannan (KGM) iyo hydroxypropyl methylcellulose (HPMC) ayaa loo qaatay sidii shayga cilmi-baarista, iyo xiirid-joogta ah, soo noqnoqda iyo imtixaannada xaaqidda heerkulka ayaa lagu sameeyay nidaamka isku-dhafka iyadoo la adeegsanayo rheometer wareeg ah. Saamaynta jajabka tirada badan ee xalku iyo saamiga isku dhafan ee viscosity iyo sifooyinka rheological ee nidaamka isku xidhka KGM/HPMC ayaa la falanqeeyay. Natiijooyinka waxay muujinayaan in nidaamka isku-dhafka ee KGM/HPMC uu yahay dareere aan Newtonian ahayn, kororka jajabka ballaaran iyo maadada KGM ee nidaamka waxay yareyneysaa dareeraha xalka isku-dhafka waxayna kordhisaa viscosity. Gobolka sol, KGM iyo silsiladaha molecular ee HPMC waxay sameeyaan qaab dhismeed aad u adag iyada oo loo marayo isdhexgalka hydrophobic. Kordhinta jajabka tirada badan ee nidaamka iyo nuxurka KGM ayaa ku habboon ilaalinta xasilloonida qaabdhismeedka. Nidaamka jajabka hooseeya ee hooseeya, kordhinta maadada KGM waxay faa'iido u leedahay samaynta jeliyeyaasha kulaylka; inta lagu jiro nidaamka jajabka tirada badan, kordhinta nuxurka HPMC waxay ku haboon tahay samaynta jel-ku-darka heerkulbeegga.

Erayada muhiimka ah:konjac glucomannan; hydroxypropyl methylcellulose; xarun; dhaqanka rheological

Polysaccharides-ka dabiiciga ah ayaa si weyn loogu isticmaalaa warshadaha cuntada sababtoo ah dhumucdooda, emulsifying iyo sifooyinka gelling. Konjac glucomannan (KGM) waa polysaccharide warshad dabiici ah, oo ka koobanβ-D-glucose iyoβ-D-mannose ee saamiga 1.6: 1, labada waxaa ku xiran byβ-1,4 glycosidic bonds, gudaha C- Waxaa jira qadar yar oo acetyl ah booska 6 (qiyaastii 1 acetyl 17-kii hadhaagaba). Si kastaba ha ahaatee, viscosity sare iyo dareere liidata ee KGM aqueous solution ayaa xaddidaya codsigeeda wax soo saarka. Hydroxypropyl methylcellulose (HPMC) waa ether propylene glycol ee methylcellulose, kaas oo iska leh ether-ka cellulose aan-ionic ahayn. HPMC waa filim sameeye, biyo-milmi kara, oo la cusboonaysiin karo. HPMC waxay leedahay viscosity hooseeya iyo xoogga jel heerkulka hooseeya, iyo waxqabadka processing xad liidata, laakiin samayn karaa ilaa xad viscous adag-sida jel heerkulka sare, sidaas darteed habab badan oo wax soo saarka waa in lagu fuliyaa heerkulka sare, taasoo keentay in wax soo saarka sare isticmaalka tamarta. Qiimaha wax-soo-saarku waa mid sarreeya. Suugaantu waxay muujinaysaa in unugga mannose-ka ee aan la bedelin ee silsiladda kelli ee KGM uu samayn karo gobol daciif ah oo isku-dhafan oo isku-dhafan oo isku-dhafan oo leh kooxda hydrophobic ee silsiladda molecular HPMC iyada oo loo marayo isdhexgalka hydrophobic. Qaab dhismeedkani wuxuu dib u dhigi karaa oo qayb ahaan ka hortagi karaa kuleylka kulaylka ee HPMC wuxuuna hoos u dhigi karaa heerkulka jel ee HPMC. Intaa waxaa dheer, marka la eego sifooyinka hoose ee viscosity ee HPMC ee heerkulka hooseeya, waxaa la saadaaliyay in isku-darka KGM ay hagaajin karto sifooyinka sare ee KGM iyo hagaajinta waxqabadkeeda. Sidaa darteed, warqadani waxay dhisi doontaa nidaamka isku dhafka KGM/HPMC si ay u sahamiso saamaynta jajabka tirada badan ee xalku iyo saamiga isku dhafka ah ee sifooyinka rheological ee nidaamka KGM/HPMC, oo ay bixiso tixraac aragtiyeed ee codsiga nidaamka iskudarka KGM/HPMC warshadaha cuntada.

1. Qalabka iyo hababka

1.1 Qalabka iyo reagents

Hydroxypropyl methylcellulose, KIMA CHEMICAL CO., LTD, jajab ballaaran 2%, viscosity 6 mPa·s; Methoxy mass jajab 28% ~ 30%; Jajabka hydroxypropyl 7.0% ~ 12%

Konjac glucomannan, Wuhan Johnson Konjac Food Co., Ltd., 1 wt% viscosity xal aqueous≥28 000 mPa·s.

1.2 Qalabka iyo qalabka

MCR92 rotational reometer, Anton Paar Co., Ltd., Austria; UPT-II-10T mashiinka biyaha ultrapure, Sichuan Youpu Ultrapure Technology Co., Ltd .; AB-50 dheelitirka falanqaynta elektiroonigga ah, shirkadda Swiss Mette; LHS-150HC qubeyska heerkulka joogtada ah, Wuxi Huaze Technology Co., Ltd .; JJ-1 Kiciyeyaasha Korontada, Warshada Qalabka Caafimaadka ee Jintan, Gobolka Jiangsu.

1.3 Diyaarinta xal isku dhafan

Ku miisaan budada HPMC iyo KGM oo leh saami isku dhaf ah oo gaar ah (saamiga tirada: 0:10, 3:7, 5:5, 7:3, 10:0), si tartiib ah ugu dar biyo deionized ah 60°C qubeyska biyaha, oo walaaq 1.5 ~ 2 h si ay si siman u kala firdhiso, oo u diyaari 5 nooc oo xalal gradient ah oo leh jajab tiro badan oo adag oo ah 0.50%, 0.75%, 1.00%, 1.25%, iyo 1.50%, siday u kala horreeyaan.

1.4 Tijaabada sifooyinka rheological ee xal isku dhafan

Tijaabada xiirid-joogta ah: Qallooca rheological ee KGM/HPMC xal isku dhafan ayaa lagu qiyaasay iyadoo la isticmaalayo koorta CP50 iyo saxan, farqiga u dhexeeya taarikada sare iyo hoose ayaa lagu hagaajiyay 0.1 mm, heerkulka cabbirku wuxuu ahaa 25°C, iyo kala duwanaanshaha heerka xiiridku wuxuu ahaa 0.1 ilaa 100 s-1.

Iskaanka cadaadiska (go'aaminta gobolka viscoelastic toosan): Adeegso saxanka PP50 si aad u cabbirto gobolka toosan ee viscoelasticka iyo isbeddelka moodada ee xalka isku dhafka ah ee KGM/HPMC, u deji kala dheeraynta ilaa 1.000 mm, soo noqnoqoshada go'an ilaa 1Hz, iyo cabirka heerkulka 25°C. Kala duwanaanshaha culeysku waa 0.1% ~ 100%.

Xaaqid joogta ah: Isticmaal saxan PP50 si aad u cabbirto isbeddelka moodeelka iyo ku-tiirsanaanta inta jeer ee xalka isku dhafka ah ee KGM/HPMC. Fogaanta waxaa lagu dejiyay 1.000 mm, culeysku waa 1%, heerkulka cabbiraadda waa 25°C, iyo inta jeer ee kala duwan waa 0.1-100 Hz.

Sawirka heerkulka: Module-ka iyo ku-tiirsanaanta ku-tiirsanaanta ku-tiirsanaanta KGM/HPMC waxaa lagu cabbiray iyadoo la adeegsanayo saxan PP50, kala dheereynta waxaa loo dejiyay 1.000 mm, inta jeer ee go'an waxay ahayd 1 Hz, cilladu waxay ahayd 1%, heerkulkuna wuxuu ahaa 25 ilaa 90°C.

2. Natiijooyinka iyo Falanqaynta

2.1 Falanqaynta qalooca socodka ee nidaamka isku dhafka KGM/HPMC

Viscosity iyo qalloocyada heerka xiirid ee xalalka KGM/HPMC oo leh saamiyo isku dhafan oo kala duwan oo jajabyo kala duwan ah. Dheecaannada ay viscosity-koodu yahay shaqo toosan oo ah heerka dhogorta waxaa loo yaqaan dareeraha Newtonian, haddii kale waxaa loo yaqaan dareeraha aan Newtonian ahayn. Waxaa laga arki karaa qalooca in viscosity ee xalka KGM iyo xalka isku dhafka KGM/HPMC uu hoos u dhaco korodhka heerka dhogorta; Mar kasta oo ay ka kooban tahay KGM, ayaa sare u kaca jajabka tirada badan ee nidaamka, iyo sida muuqata ifafaalaha khafiifinta xiirta ee xalka. Tani waxay tusinaysaa in KGM iyo nidaamka isku xidhka ee KGM/HPMC ay yihiin dareere aan Newtonian ahayn, iyo nooca dareeraha ee habka isku xidhka KGM/HPMC waxaa inta badan go'aamiya KGM.

Laga soo bilaabo index socodka iyo isku dhafka viscosity ee xalalka KGM/HPMC oo leh jajabyo kala duwan iyo saamiyo isku dhafan oo kala duwan, waxaa la arki karaa in qiimaha n ee KGM, HPMC iyo KGM/HPMC ay dhamaantood ka yar yihiin 1, taas oo muujinaysa in xalalku yihiin dhammaan dareerayaasha pseudoplastic. Nidaamka isku dhafka ah ee KGM/HPMC, kororka jajabka ballaaran ee nidaamka wuxuu keeni doonaa isdhexgalka iyo isdhexgalka kale ee ka dhexeeya HPMC iyo KGM silsiladaha molecular ee xalka, taas oo yareyn doonta dhaqdhaqaaqa silsiladaha molecular, taas oo hoos u dhigi doonta qiimaha n nidaamka. Isla mar ahaantaana, korodhka nuxurka KGM, isdhexgalka ka dhexeeya silsiladaha molecular ee KGM ee nidaamka KGM/HPMC waa la wanaajiyey, taas oo hoos u dhigaysa dhaqdhaqaaqeeda waxayna keenaysaa hoos u dhaca qiimaha n. Taas beddelkeeda, qiimaha K ee xalka isku dhafka ah ee KGM/HPMC ayaa si isdaba joog ah u kordheysa iyadoo ay korortay jajabka tirada badan ee xalku iyo ka kooban yahay KGM, taas oo inta badan ay sabab u tahay kororka jajabka tirada nidaamka iyo nuxurka KGM, kuwaas oo labaduba kordhiya nuxurka kooxaha hydrophilic ee nidaamka. , kordhinta isdhexgalka molecular gudaha silsiladda molecular iyo inta u dhaxaysa silsiladaha, taas oo kordhinaysa radius hydrodynamic ee molecule, taas oo ka dhigaysa in ay yar tahay in lagu jihaysto ficilka xoogga dhogorta dibadda iyo kordhinta viscosity.

Qiimaha aragtiyeed ee viscosity eber-xiirid ee nidaamka isku xidhka KGM/HPMC waxaa lagu xisaabin karaa iyadoo la raacayo mabda'a soo koobida logarithmic ee kore, iyo qiimaheeda tijaabada ah waxaa heli kara Carren oo ku habboon ka saarista qalooca heerka viscosity-xiirid. Marka la barbardhigo qiimaha la saadaaliyay ee viscosity eber-xiirid ee nidaamka isku dhafka KGM/HPMC oo leh jajabyo kala duwan iyo saamiyo isku dhafan oo kala duwan oo leh qiimaha tijaabada ah, waxaa la arki karaa in qiimaha dhabta ah ee viscosity eber-xiirid ee xarunta KGM/HPMC xalku wuu ka yar yahay qiimaha aragtida. Tani waxay muujisay in shir cusub oo qaab-dhismeed cufan leh lagu sameeyay nidaamka qalafsan ee KGM iyo HPMC. Daraasadaha jira ayaa muujiyay in unugyada mannose-ka ee aan la bedelin ee silsiladda molecular ee KGM ay la falgali karaan kooxaha hydrophobic ee silsiladda molecular ee HPMC si ay u sameeyaan gobol urureed hydrophobic ah oo daciif ah. Waxaa la qiyaasayaa in qaabka cusub ee isu-ururinta oo leh qaab-dhismeed cufan inta badan lagu sameeyay isdhexgalka hydrophobic. Marka saamiga KGM uu hooseeyo (HPMC> 50%), qiimaha dhabta ah ee viscosity eber jeexjeexa ee nidaamka KGM/HPMC wuu ka hooseeyaa qiimaha aragtida, taas oo muujinaysa in maaddada KGM ee hoose, molecules badan ay ka qayb qaataan cufan cusub qaab dhismeedka. Samaynta , mawjadaha eber-xiirid ee nidaamka ayaa sii yaraanaya.

2.2 Falanqaynta qaloocyada xaaqidda cadaadiska ee nidaamka isku-xidhka KGM/HPMC

Laga soo bilaabo qalooca xiriirka modules iyo dhogorta xiiran ee xalalka KGM/HPMC ee leh jajabyo kala duwan iyo saamiyo isku dhafan oo kala duwan, waxaa la arki karaa marka cirridka xiiridu uu ka yar yahay 10%, G"iyo G"Nidaamka isku dhafan asal ahaan ha ku kordhin cadaadiska xiirta. Si kastaba ha ahaatee, waxay muujinaysaa in gudaha kala duwanaanshahan dhogorta ah, nidaamka isku dhafan uu ka jawaabi karo kicinta dibadda iyada oo loo marayo isbeddelka isugeynta silsiladda molecular, iyo qaab-dhismeedka nidaamka isku-dhafka ah ma dhaawacmo. Marka cirridka xiiridu uu yahay> 10%, dibedda Marka loo eego ficilka xoogga xiiridda, xawaaraha kala-baxa ee silsiladaha molecular ee nidaamka kakan ayaa ka weyn xawaaraha isku-xirnaanta, G"iyo G"bilow inaad hoos u dhigto, nidaamkuna wuxuu galaa gobolka viscoelastic-ka ee aan tooska ahayn. Sidaa darteed, imtixaankii soo noqnoqda ee firfircoon ee xiga, cabbirka cadaadiska xiiridda ayaa loo doortay 1% si loo tijaabiyo.

2.3 Falanqaynta xaaqida soo noqnoqda ee nidaamka isku dhafka KGM/HPMC

Qalloocyada kala duwan ee moduleska kaydinta iyo modules luminta inta jeer ee xalalka KGM/HPMC oo leh saamiyo isku dhafan oo kala duwan oo hoos yimaada jajabyo kala duwan. Module-ka kaydinta G' waxa uu ka dhigan yahay tamarta dib loo soo celin karo ka dib kaydinta ku meel gaadhka ah ee imtixaanka, iyo luminta moduleska G" macnaheedu waa tamarta loo baahan yahay socodka bilowga ah, taas oo ah khasaare aan dib loo celin karin oo ugu dambeyntii isu beddelaya kulaylka. Waxaa la arki karaa in, iyadoo inta jeer ee oscillation uu kordho, modules khasaaro G"had iyo jeer waa ka weyn yahay moduleska kaydinta G", oo muujinaya dabeecad dareere ah. Kala duwanaanshaha soo noqnoqda tijaabada, modules-ka kaydinta G' iyo luminta moduleska G" waxay kordheen korodhka soo noqnoqda oscillation. Tani waxay inta badan sabab u tahay xaqiiqda ah in kororka soo noqnoqda oscillation, qaybaha silsiladda kelli ee nidaamka ma haystaan ​​wakhti ay ku soo kabtaan cilladda waqti gaaban Dawladdii hore, sidaas awgeed waxay muujinaysaa ifafaale in tamar badan lagu kaydin karo ( ka weyn G") ama u baahan in la lumiyo (G").

Kordhinta soo noqnoqda oscillation-ka, modules-ka kaydinta nidaamka ayaa si lama filaan ah hoos ugu dhacaya, iyo kororka jajabka tirada iyo KGM ee nidaamka, barta inta jeer ee hoos u dhaca lama filaan ah ayaa si tartiib tartiib ah u kordheysa. Hoos u dhaca lama filaanka ah ayaa laga yaabaa inay sabab u tahay burburinta qaabdhismeedka is haysta ee ay sameeyeen ururka hydrophobic ee u dhexeeya KGM iyo HPMC ee nidaamka iyadoo la xiiro dibadda. Waxaa intaa dheer, kororka jajabka xajmiga nidaamka iyo maadada KGM waxay faa'iido u leedahay in la ilaaliyo xasilloonida qaabdhismeedka cufan, waxayna kordhisaa qiimaha soo noqnoqda dibadda ee burburiya dhismaha.

2.4 Falanqaynta qalooca iskaanka heerkulka ee nidaamka isku dhafan ee KGM/HPMC

Laga soo bilaabo qalooca modules kaydinta iyo modules luminta KGM/HPMC xalal kala duwan oo jajabyo kala duwan iyo saamiyo isku dar ah oo kala duwan, waxaa la arki karaa marka jajabka tirada badan ee nidaamka waa 0.50%, G"iyo G"Xalka HPMC si dhib leh uma beddelo heerkulka. iyo G">G", viscosity ee nidaamka ayaa xukuma; marka jajabku bato, G"Xalka HPMC marka hore isma beddelo ka dibna si xoog leh ayuu u kordhaa, iyo G"iyo G"isku xidha ilaa 70°C (Heerkulka barta is-goysku waa barta jelka), nidaamkuna wuxuu sameeyaa jel wakhtigan, taas oo muujinaysa in HPMC uu yahay jel kuleyl leh. Xalka KGM, marka tirada guud ee nidaamka ay tahay 0.50% iyo 0.75%, G"iyo G ee nidaamka “wuxuu muujinayaa isbeddel hoos u dhac ah; marka jajabku bato, G' iyo G" ee xalka KGM ayaa marka hore hoos u dhacaya ka dibna si weyn u kordhaya, taas oo muujinaysa in xalka KGM uu muujinayo sifooyin-jeel ah oo jajab ah oo sarreeya iyo heerkul sare.

Kor u kaca heerkulka, G"iyo G"Nidaamka kakan ee KGM/HPMC ayaa markii hore hoos u dhacay ka dibna si weyn u kordhay, iyo G"iyo G"u muuqday dhibcaha isgoysyada, nidaamkuna wuxuu sameeyay jel. Marka molecules HPMC ay ku jiraan heerkul hooseeya, isku xidhka hydrogen wuxuu ka dhex dhacaa kooxaha hydrophilic ee silsiladda molecular iyo molecules biyaha, iyo marka heerkulku kordho, kulaylka la dabaqay wuxuu baabi'iyaa curaarta hydrogen ee u dhexeeya HPMC iyo molecules biyaha, taasoo keentay samaynta HPMC macromolecular. silsilado. Kooxaha hydrophobic ee dusha sare ayaa soo baxa, ururka hydrophobic ayaa dhacaya, iyo jel heerkulbeeg ah ayaa la sameeyay. Nidaamka jajabka tirada yar ee hooseeya, waxyaabo badan oo KGM ah ayaa sameyn kara jel; Nidaamka jajabka tirada badan, waxyaabo badan oo HPMC ah ayaa sameyn kara jel. Nidaamka jajabka hooseeya ee hooseeya (0.50%), joogitaanka molecules KGM waxay yaraynaysaa suurtogalnimada samaynta bonds hydrogen ee u dhexeeya molecules HPMC, taas oo kordhinaysa suurtogalnimada soo-gaadhista kooxaha hydrophobic ee molecules HPMC, taas oo u sahlaysa samaynta jeels heerkulbeeg ah. Nidaamka jajabka sare ee tirada badan, haddii nuxurka KGM uu aad u sarreeyo, viscosity ee nidaamku waa sarreeyaa, taas oo aan ku habboonayn ururka hydrophobic ee u dhexeeya HPMC iyo KGM molecules, taas oo aan ku habboonayn samaynta jel thermogenic.

3. Gabagabo

Warqadan, habdhaqanka rheological ee nidaamka isku dhafka ee KGM iyo HPMC ayaa lagu bartay. Natiijooyinka waxay muujinayaan in nidaamka isku dhafka ee KGM/HPMC uu yahay dareere aan Newtonian ahayn, iyo nooca dareeraha ee nidaamka isku dhafka ee KGM/HPMC waxaa inta badan go'aamiya KGM. Kordhinta jajabka ballaaran ee nidaamka iyo nuxurka KGM labaduba waxay hoos u dhigeen dareeraha xalka isku dhafka waxayna kordhiyeen viscosity. Gobolka sol, silsiladaha molecular ee KGM iyo HPMC waxay sameeyaan qaab dhismeed cufan iyada oo loo marayo isdhexgalka hydrophobic. Qaab dhismeedka nidaamka waxaa burburiyay xiirid dibadda ah, taasoo keentay hoos u dhac lama filaan ah oo ku yimid moduleska kaydinta nidaamka. Kordhinta jajabka xajmiga nidaamka iyo nuxurka KGM ayaa faa'iido u leh in la ilaaliyo xasilloonida qaabdhismeedka cufan iyo kordhinta qiimaha soo noqnoqda dibadda ee burburiya dhismaha. Nidaamka jajabka hooseeya ee hooseeya, waxyaabo badan oo KGM ah ayaa ku habboon samaynta jel; nidaamka jajabka tirada badan, wax badan oo ka mid ah HPMC ayaa ku habboon samaynta jel.