Hydroxypropyl Methylcellulose (HPMC) Heerka Nadiifiyeha Gacanta

Hydroxypropyl Methylcellulose (HPMC) Heerka Nadiifiyeha Gacanta

Hydroxypropyl Methylcellulose (HPMC) waa polymer si weyn looga isticmaalo dawooyinka, qurxinta, iyo warshadaha daryeelka shakhsi ahaaneed iyadoo ay ugu wacan tahay sifooyinkeeda gaarka ah sida dhumucyada, emulsifying, xasilinta, iyo haysashada biyaha. Sanadihii la soo dhaafay, HPMC waxay heshay fiiro gaar ah sida qayb muhiim ah oo ka mid ah nadiifiyeyaasha gacmaha sababtoo ah awoodda ay u leedahay inay kor u qaaddo waxtarka, texture, iyo guud ahaan waxqabadka alaabta.

Marka ay timaado nadaafadda gacmaha, doorashada darajada ku habboon ee HPMC waa muhiim si loo hubiyo waxqabadka la doonayo iyo xasilloonida qaabeynta. Astaamaha muhiimka ah ee HPMC ee khuseeya codsiyada gacmo nadiifiyaha waa viscosity, size particle, iyo methoxy iyo hydroxypropyl content.

Guud ahaan, darajada viscosity sare ee HPMC ayaa loo door biday qaabaynta gacmo nadiifiyaha si loo hubiyo dhumuc ku filan iyo guryaha fidinta ee la hagaajiyay. Viscosity ee HPMC waxay u dhaxayn kartaa mid hoose ilaa sare, iyadoo doorashadu ku xidhan tahay qaabaynta gaarka ah iyo shuruudaha codsiga. Nadiifiyeyaasha gacmaha, heerka viscosity ee 100,000-200,000 cps ayaa caadi ahaan loo isticmaalaa.

Baaxadda walxaha HPMC waa tixgalin kale oo muhiim u ah qaabaynta gacmo nadiifiyaha. Cabbirka walxaha khafiifka ah ayaa la door bidaa si loo hubiyo kala firdhinta degdega ah ee qaabaynta. Cabbirka walxaha 100 mesh ama ka fiican ayaa caadi ahaan lagula talinayaa codsiyada gacmo nadiifiyaha.

Marka la eego maadada methoxy iyo hydroxypropyl, saamiga ugu habboon ee labadan qaybood waxay kuxirantahay qaabaynta gaarka ah iyo sifooyinka la rabo. Guud ahaan, maadada hydroxypropyl ee sare waxay keentaa haynta biyaha iyo hagaajinta guryaha gelation, halka maadada methoxy ee sare ay hagaajinayso sifooyinka sameynta filimada iyo dhejinta. Codsiyada gacmo nadiifiyaha, waxa ku jira hydroxypropyl oo ah 9-12% iyo maadada methoxy ee 28-32% ayaa si caadi ah loo isticmaalaa.

Waxa kale oo muhiim ah in la tixgeliyo tayada iyo nadiifnimada HPMC ee loo isticmaalo qaabaynta gacmo nadiifiyaha. HPMC waa in ay ka xorowdaa wasakhda iyo wasakhda saamayn karta waxtarka iyo badbaadada alaabta. Waxaa lagu talinayaa in HPMC laga keeno soosaarayaal sumcad leh kuwaas oo leh rikoor la xaqiijiyay oo ah soo saarista alaab tayo sare leh oo buuxisa shuruudaha loo baahan yahay.

Guud ahaan, doorashada darajada ku habboon ee HPMC ayaa muhiim u ah waxqabadka iyo xasilloonida qaabaynta gacmo nadiifiyaha. Waxyaabaha sida viscosity, cabbirka walxaha, iyo methoxy iyo hydroxypropyl ka kooban yahay waa in si taxadar leh loo tixgeliyo si loo hubiyo waxqabadka ugu fiican iyo badbaadada alaabta.