Yakaderera-inotsiva hydroxypropylmethylcellulose (L-HPMC) i polymer inoshanda zvakasiyana-siyana ine maapplication mumaindasitiri akasiyana siyana, anosanganisira emishonga, chikafu, kuvaka, uye zvekuzora. Mushonga uyu unotorwa kubva ku cellulose, polima yemusikirwo inowanikwa mumadziro esero rezvirimwa. Kuti unzwisise yakaderera-inotsiva hydroxypropyl methylcellulose, munhu anofanirwa kuputsa zita rayo uye kuongorora zvimiro zvayo, mashandisiro, synthesis, uye kukanganisa kumaindasitiri akasiyana.
1. Kunzwisisa kwemazita:
Hydroxypropyl methylcellulose (HPMC):
Cellulose i carbohydrate yakaoma inoumbwa neglucose mayunitsi uye ndiyo chikamu chikuru chechirimwa masero madziro.
Hydroxypropyl methylcellulose imhando yakagadziridzwa yeselulosi iyo yakabatwa nemakemikari kuunza hydroxypropyl uye methyl mapoka. Iyi shanduko inowedzera kunyungudika kwayo uye zvimwe zvinodiwa.
Kutsiva kwakaderera:
Zvinoreva kune yakaderera dhigirii yekutsiva kana ichienzaniswa nezvimwe zvinobva kune cellulose, senge zvakatsiviwa zvakanyanya senge hydroxyethyl cellulose (HEC).
2. Kuita:
Solubility:
L-HPMC inonyanya kunyungudika mumvura kupfuura cellulose.
Viscosity:
Iyo viscosity yeL-HPMC mhinduro inogona kudzorwa nekugadzirisa dhigirii rekutsiva, ichiita kuti ive yakakodzera kune dzakasiyana siyana dzekushandisa.
Kugadzira firimu:
L-HPMC inogona kugadzira mafirimu matete, ichiita kuti ishandiswe mumhando dzakasiyana dzekuputira.
Thermal kugadzikana:
Iyo polymer inowanzo ratidza kugadzikana kwakanaka kwekupisa, zvichibatsira mukusiyana kwayo mumatanho akasiyana.
3. Synthesis:
Etherification:
Iyo synthesis inosanganisira etherification ye cellulose ine propylene oxide kuunza hydroxypropyl mapoka.
Inotevera methylation ine methyl chloride inowedzera methyl mapoka kune cellulose musana.
Iyo dhigirii yekutsiva inogona kudzorwa panguva yekubatanidza kuti uwane inodiwa zvivakwa.
4. Application:
A. Pharmaceutical industry:
Binders uye disintegrants:
Inoshandiswa sebhainda mukugadzirwa kwepiritsi kuti isungirire zvinhu pamwechete.
Inoita se disintegrant kukurudzira kuparara kwemapiritsi mumagetsi ekudya.
Sustained release:
L-HPMC inoshandiswa mukugadzirisa-kusunungurwa kwemaitiro, zvichiita kuti mushonga usunungurwe zvishoma nezvishoma nekufamba kwenguva.
Topical gadziriro:
Inowanikwa mumakirimu, gels uye mafuta, inopa viscosity uye inovandudza kupararira kwemafomu.
B. Indasitiri yezvekudya:
Thickener:
Inowedzera viscosity yechikafu uye inovandudza magadzirirwo uye muromo.
stabilizer:
Inowedzera kugadzikana kwe emulsions uye suspensions.
Kugadzira firimu:
Mafirimu anodyiwa ekurongedza chikafu.
C. Indasitiri yekuvaka:
Doka nesimende:
Inoshandiswa semvura inochengetedza mumiriri mune simende-yakavakirwa zvinhu.
Kuvandudza kushanda uye kunamatira kwemateki evhu.
D. Cosmetics:
Zvigadzirwa zvekuchengeta wega:
Inowanikwa mumakirimu, lotions uye shampoos kubatsira kuvandudza magadzirirwo uye kugadzikana.
Inoshandiswa semugadziri wekugadzira firimu mune zvizorwa.
5. Kutarisira:
FDA Yakatenderwa:
L-HPMC inowanzo zivikanwa seyakachengeteka (GRAS) neUS Food and Drug Administration (FDA).
Kutevedzera mitemo yemitemo kwakakosha pakushandiswa kwayo mumishonga uye chikafu.
6. Zvinetso uye tarisiro yeramangwana:
Biodegradability:
Kunyangwe cellulose-based mapolymers achiwanzoonekwa seanogona kuparara, huwandu hwe biodegradation yeakagadziridzwa cellulose derivatives inoda kumwe kuferefetwa.
Sustainability:
Kutsvaga kwakasimba kwezvinhu zvekushandisa uye nzira dzekugadzira dzine hushamwari inzvimbo dzinoramba dzichitariswa.
7. Mhedziso:
Yakaderera-inotsiva hydroxypropyl methylcellulose inoratidza huchenjeri hwekugadzirisa kemikari mukushandisa zvimiro zvemapolima echisikigo. Zvishandiso zvaro zvakasiyana mumaindasitiri akasiyana zvinoratidzira kukosha kwayo mukugadzira kwemazuva ano. Sezvo kufambira mberi kwetekinoroji uye kusimba kunotora nzvimbo yepakati, kuenderera mberi nekuongorora uye kunatsiridzwa kweL-HPMC uye makomisheni akafanana anogona kuumba ramangwana rezvinhu zvesainzi uye maindasitiri maitiro.
Nguva yekutumira: Zvita-26-2023