Kugadziriswa-kusunungurwa uye kudzorwa-kusunungurwa kugadzirira: Cellulose ethers yakadai seHPMC (hydroxypropyl methylcellulose) inowanzoshandiswa se hydrogel skeleton zvinhu mukugadzirisa-kusunungurwa kwekugadzirira. Inogona kudzora kuburitswa kwezvinodhaka mumuviri wemunhu kuti uwane mhedzisiro yekurapa. Yakaderera-viscosity giredhi HPMC inogona kushandiswa seanonamira, thickener uye kumisa mumiririri, nepo yakakwirira-viscosity giredhi HPMC inoshandiswa kugadzirira yakasanganiswa zvinhu skeleton inosimudzira-kuburitswa mahwendefa, inosimudzira-kuburitswa capsules, uye hydrophilic gel skeleton inosimudzira-kuburitsa mahwendefa.
Coating film-forming agent: HPMC ine yakanaka firimu-forming properties, uye firimu rakaumbwa rakafanana, rakajeka, rakaoma, uye hazvisi nyore kutevedzera. Inogona kuvandudza kugadzikana kwemushonga uye kudzivirira kubuda kwemavara. The common concentration of HPMC is 2% to 10%.
Mishonga inobatsira: Cellulose ethers inoita basa rakakosha mukugadzirira kuumbwa sezvishandiso zvemishonga, senge mapellet anoramba achiburitswa, skeleton gadziriro yekuburitswa-yakagadziriswa, yakavharwa-yakagadziriswa-kuburitswa gadziriro, inoenderera-kuburitsa makapu, inosimudzira-inoburitswa-inoburitsa zvinodhaka mafirimu, resin zvinodhaka. kusunungurwa gadziriro uye mvura inosimudzira-kusunungurwa gadziriro.
Microcrystalline Cellulose (MCC): MCC imhando ye cellulose inoshandiswa zvakanyanya muindasitiri yemishonga, kunyanya mukutsikirira kwakananga uye yakaoma granulation maitiro senge roller compaction kugadzirira compressed mapiritsi kana granules.
Bioadhesives: Cellulose ethers, kunyanya nonionic uye anionic ether derivatives yakadai seEC (ethylcellulose), HEC (hydroxyethylcellulose), HPC (hydroxypropylcellulose), MC (methylcellulose), CMC (carboxymethylcellulose) kana HPMC (hydroxypropylmethylsive cellulose inoshandiswa mu bio). Aya mapolymers anogona kushandiswa mumuromo, ocular, vaginal uye transdermal bioadhesives, ega kana musanganiswa nemamwe mapolymer.
Thickeners uye Stabilizers: Cellulose derivatives anoshandiswa zvakanyanya kukora mhinduro dzezvinodhaka uye kuparadzira masisitimu senge emulsions uye kumiswa. Aya mapolymers anogona kuwedzera viscosity yeasiri-aqueous mishonga yemushonga senge organic-based coating solutions. Kuwedzera viscosity yemishonga mhinduro inogona kuvandudza bioavailability ye topical uye mucosal kugadzirira.
Fillers: Cellulose uye zvinobva mairi zvinowanzoshandiswa semafirita mune yakasimba dosage mafomu akadai semapiritsi nemakapisi. Iwo anowirirana nezvimwe zvakawanda zvinobatsira, pharmacologically inert, uye kwete kugayiwa neanhu gastrointestinal enzymes.
Binders: Cellulose ethers inoshandiswa semabhandi panguva yekugadzira granulation kubatsira magranules kuumba uye kuchengetedza kuvimbika kwawo.
Plant capsules: Cellulose ethers anoshandiswawo kugadzira macapsules ezvirimwa, imwe nzira ine ushamwari kune zvakatipoteredza kune echinyakare akatorwa nemhuka.
Mishonga yekuendesa zvinodhaka: Cellulose ethers inogona kushandiswa kugadzira nzira dzakasiyana-siyana dzekuendesa zvinodhaka, kusanganisira kudzorwa-kusunungurwa uye kunonoka-kusunungurwa-maitiro, pamwe chete nehurongwa hwenzvimbo-yakananga kana nguva-yakananga kusunungurwa kwezvinodhaka.
Iko kushandiswa kwema cellulose ethers muindasitiri yemishonga inoramba ichikura, uye nekuvandudzwa kwemafomu matsva emushonga uye maexcipients matsva, chiyero chemusika chinodiwa chinotarisirwa kuwedzera mberi.
Nguva yekutumira: Oct-31-2024