Ndeapi magiredhi akasiyana eHPMC?

HPMC, kana hydroxypropyl methylcellulose, imhando ye cellulose inotorwa inowanzoshandiswa seyakakora, emulsifier, uye stabilizer mumhando dzakasiyana dzezvigadzirwa. Ihwo hupfu huchena, husina hwema, husina kunaka hunonyungudika mumvura inotonhora uye husinganyunguriki mumvura inopisa.

HPMC inowanikwa mumhando dzakasiyana siyana, imwe neimwe iine yayo yakasarudzika zvivakwa uye mashandisirwo. Magiredhi eHPMC anobva padanho rekutsiva (DS) remapoka ehydroxypropyl, inova chiyero chehuwandu hwemapoka ehydroxypropyl pachikamu cheanhydroglucose. Iyo yakakwirira yeDS, iyo yakawanda hydroxypropyl mapoka aripo uye iyo yakawanda hydrophilic iyo HPMC iri.

Magiredhi eHPMC akakamurwa kuita mapoka matatu makuru: yakaderera DS, yepakati DS, uye yakakwira DS.

Yakaderera DS HPMC inowanzo shandiswa mumashandisirwo uko yakaderera viscosity uye yakaderera gel simba inodiwa. Iri giredhi rinowanzo shandiswa mukugadzira chikafu nechinwiwa, senge aizikirimu, sosi, uye giravi. Inoshandiswawo mumishonga yemishonga, yakadai semapiritsi uye capsules.

Yepakati DS HPMC inoshandiswa mumashandisirwo uko yakakwirira viscosity uye gel simba rinodiwa. Iri giredhi rinowanzo shandiswa mukudya uye zvinwiwa kunyorera, senge jamu uye jellies, pamwe nekushandisa kwemishonga, senge zvizoro nemafuta.

Yakakwira DS HPMC inoshandiswa mumashandisirwo uko yakanyanya kukwirisa viscosity uye simba regel rinodiwa. Iri giredhi rinowanzo shandiswa muchikafu uye chinwiwa kunyorera, senge chizi uye yogati, pamwe nekushandisa kwemishonga, senge suppositories uye pessaries.

Pamusoro pemapoka matatu makuru eHPMC, kune zvakare akati wandei madiki. Aya ma subcategories akavakirwa padanho rekutsiva, saizi yechikamu, uye rudzi rweboka rehydroxypropyl.

Iyo dhigirii yekutsiva subcategories yakavakirwa padanho rekutsiviwa kwemapoka ehydroxypropyl. Zvikamu izvi zvakaderera DS (0.5-1.5), yepakati DS (1.5-2.5), uye yakakwirira DS (2.5-3.5).

Iyo particle size subcategories inoenderana nehukuru hwezvimedu. Zvikamu izvi zvakanaka (zvisingasviki gumi microns), zvepakati (10-20 microns), uye zvakakasharara (kupfuura 20 microns).

Mhando ye hydroxypropyl group subcategories yakavakirwa pamhando yehydroxypropyl boka riripo muHPMC. Aya ma subcategories anoti hydroxypropyl methylcellulose (HPMC), hydroxypropyl ethylcellulose (HPEC), uye hydroxypropyl cellulose (HPC).

HPMC chinhu chinogoneka uye chinoshandiswa zvakanyanya mumhando dzakasiyana dzezvigadzirwa. Iwo magiredhi akasiyana eHPMC akavakirwa padanho rekutsiva, saizi yechikamu, uye mhando yeboka rehydroxypropyl, uye giredhi rega rega rine zvivakwa zvaro uye mashandisiro.