HPMC inonzi hydroxypropyl methylcellulose, inova isiri-ionic cellulose yakasanganiswa ether yakagadzirwa kubva kudonje rakanatswa mushure me alkalization, uchishandisa propylene oxide uye methyl chloride se etherification agents, uye kuburikidza neakatevedzana maitiro. Dhigirii rekutsiva kazhinji 1.2 ~ 2.0. Zvimiro zvaro zvakasiyana nekuda kweiyo reshiyo yakasiyana yemethoxyl yemukati uye hydroxypropyl yemukati.
MC ndeye methyl cellulose, iyo inogadzirwa necellulose ethernekurapa donje rakanatswa nealkali, kushandisa methane chloride se etherification agent, uye nekuenda kuburikidza neakatevedzana maitiro. Kazhinji, dhigirii rekutsiva i1.6 ~ 2.0, uye kunyungudika kwakasiyanawo nemadhigirii akasiyana ekutsiva. Iyo ndeye isiri-ionic cellulose ether.
Kuenzanisa kwekuita pakati pezviviri:
(1) Hydroxypropyl methylcellulose inonyungudika nyore nyore mumvura inotonhora, uye ichasangana nematambudziko mukunyungudika mumvura inopisa. Asi tembiricha yayo yegelation mumvura inopisa yakanyanya kukwirira kupfuura yemethyl cellulose. Iyo solubility mumvura inotonhora zvakare yakagadziridzwa zvakanyanya kana ichienzaniswa nemethyl cellulose. Hydroxypropyl methylcellulose yakagadzikana kune acid uye alkali, uye mhinduro yayo ine aqueous yakagadzikana muhuwandu hwepH = 2 ~ 12. Caustic soda uye mvura yeraimu haina mhedzisiro pakuita kwayo, asi alkali inogona kukurumidzira kuparara kwayo uye kuwedzera viscosity yayo. Hydroxypropyl methylcellulose yakagadzikana kune yakajairwa munyu, asi kana kusanganiswa kwemunyu munyu kwakakwira, viscosity yehydroxypropyl methylcellulose mhinduro inowedzera kuwedzera.
Methylcellulose zvakare yakanyungudika mumvura inotonhora, uye zvichave zvakaoma kunyungudika mumvura inopisa. Mushonga wayo une aqueous wakanyatsogadzikana muhupamhi hwepH = 3 ~ 12. Iine kuwirirana kwakanaka ne starch, guar gum, nezvimwewo uye akawanda ma surfactants. Kana tembiricha inosvika tembiricha yegelation, gelation inoitika.
(2) Iyo viscosity yehydroxypropyl methylcellulose inoenderana nehuremu hwayo hwemamorekuru, uye iyo yakakura huremu hwemamorekuru, inokwirisa viscosity. Kupisa kunokanganisawo viscosity yayo, sezvo tembiricha inowedzera, viscosity inoderera. Nekudaro, iyo yakakwira viscosity ine yakaderera tembiricha mhedzisiro pane methyl cellulose. Mushonga waro wakagadzikana kana wakachengetwa pakushambidzika kwekamuri.
Methylcellulose ine mhedzisiro yakakosha pakushanda uye kunamatira kwedhaka. “Kunamira” pano kunoreva simba rekunamira rinonzwikwa pakati pemudziyo wemudziyo wekushandisa nemadziro emadziro, ndiko kuti, kugerwa kwedhaka. Kunamatira kwakakwirira, kupikisa kweshear kwevhu kwakakura, uye simba rinodiwa nevashandi vari mukugadzirisa kushandiswa kwakakurawo, uye kushanda kwekuvaka kwedhaka kwakashata. Methyl cellulose adhesion iri pamwero wepakati mune cellulose ether zvigadzirwa.
(3) Kuchengetwa kwemvura kwehydroxypropyl methylcellulose kunoenderana nehuwandu hwayo hwekuwedzera, viscosity, nezvimwewo, uye chiyero chekuchengetedza mvura pasi peiyo imwechete yekuwedzera yakakwira kupfuura iyo yemethyl cellulose.
Kuchengetwa kwemvura kwemethylcellulose kunoenderana nehuwandu hwayo hwekuwedzera, viscosity, particle fineness uye dissolution rate. Kazhinji, kana huwandu hwekuwedzera hwakakura, hunyoro hudiki, uye viscosity yakakura, mwero wekuchengetedza mvura wakakwira. Pakati pavo, huwandu hwekuwedzera hune simba guru pahuwandu hwekuchengetedza mvura, uye chiyero che viscosity hachina kuenzana zvakananga nehuwandu hwekuchengetedza mvura. Mwero wekunyungudika unonyanya kuenderana nehuwandu hwekugadziriswa kwepasi kwe cellulose particles uye particle fineness. Pakati pema cellulose ethers ari pamusoro, methyl cellulose uye hydroxypropyl methyl cellulose vane mwero wepamusoro wekuchengetedza mvura.
(4) Hydroxypropyl methylcellulose inogona kusanganiswa nemvura-soluble polymer compounds kuita yunifomu uye yakakwirira viscosity mhinduro. Zvakadai sepolyvinyl doro, starch ether, yemiriwo gum, etc. Iko kunamatira kwehydroxypropyl methylcellulose kune dhaka rekuvaka yakakwirira kudarika yemethylcellulose.
Hydroxypropyl methylcellulose ine nani enzyme kuramba kupfuura methylcellulose, uye mhinduro yayo kashoma kuderedzwa nema enzymes kupfuura methylcellulose.
Kuchinja kwekushisa kunogona kukanganisa zvakanyanya kuchengetwa kwemvura yemethyl cellulose. Kazhinji, kukwirisa tembiricha, kunowedzera kuchengetedzeka kwemvura. Kana tembiricha yevhu ichipfuura 40 ° C, kuchengetwa kwemvura kwemethyl cellulose kuchaderedzwa zvakanyanya, kunokanganisa zvakanyanya kuvakwa kwedhaka. Kana tembiricha yakakwira, edza kusarudza hydroxypropyl methylcellulose.
Nguva yekutumira: Zvita-20-2022