Hydroxypropyl methylcellulose kurasikirwa uremu

Nhanganyaya

Hydroxypropyl methylcellulose (HPMC) inoshandiswa zvakanyanya polymeric zvinhu mumaindasitiri ezvekudya, emishonga, uye zvekuzora. Iyo inonyungudika mumvura, isiri-ionic, uye biodegradable polymer inotorwa kubva ku cellulose. HPMC yakashandiswa kwemakore akawanda seyakakora mumiriri, emulsifier, stabilizer, uye gelling mumiriri mune zvakasiyana zvigadzirwa zvekudya. Mumakore achangopfuura, yakawanikwa iine zvinogona kushandiswa mukurasikirwa nekurema.

Nzira Yekuita

HPMC inonzi hydrophilic polymer inokwanisa kutora mvura uye kuzvimba kuita gel. Iyi gel-yakafanana chimiro inofungidzirwa kuti inokonzera kukwanisa kwayo kuderedza kudya uye kukurudzira satiety. Zvinotendwa kuti gel-sechimiro cheHPMC chinoumba chipingamupinyi chemuviri mudumbu, chinoderedza kubatwa kwechikafu uye kuwedzera kunzwa kwekuzara. Uyezve, HPMC inofungidzirwa kuderedza kutorwa kwemafuta uye makhahydrates, izvo zvinogona kutungamirira mukurasikirwa.

Clinical Evidence

Pakave nezvidzidzo zvekiriniki zvakati kuti zvakaongorora mhedzisiro yeHPMC pakurasikirwa nehuremu. Muchidzidzo chisina kujairika, chakapetwa kaviri, chinodzorwa ne placebo, zvidzidzo zvakapihwa HPMC kana placebo kwemavhiki masere. Pakupera kwechidzidzo, vanhu vakanga vatora HPMC vakanga varasikirwa zvakanyanya kudarika avo vakanga vatora placebo. Mune imwe ongororo, zvidzidzo zvakapihwa ingave HPMC kana placebo kwemavhiki gumi nemaviri. Pakupera kwechidzidzo, vanhu vakanga vatora HPMC vakanga varasikirwa zvakanyanya kudarika avo vakanga vatora placebo.

Pamusoro pezvidzidzo izvi, pakave nezvimwe zvidzidzo zvakati wandei zvakaongorora mhedzisiro yeHPMC pakurasikirwa nehuremu. Muchidzidzo chisina kujairika, chakapetwa kaviri, chinodzorwa ne placebo, zvidzidzo zvakapihwa HPMC kana placebo kwemavhiki masere. Pakupera kwechidzidzo, vanhu vakanga vatora HPMC vakanga varasikirwa zvakanyanya kudarika avo vakanga vatora placebo.

Safety

HPMC inowanzoonekwa seyakachengeteka kudyiwa nevanhu. Kazhinji inobvumirwa zvakanaka uye ine mhedzisiro shoma. Migumisiro yakajairika inoshumwa ndeyekugumbuka kwegastrointestinal, sekusvotwa, kurutsa, uye manyoka. Pamusoro pezvo, HPMC inogona kudyidzana nemimwe mishonga, saka zvakakosha kuonana nemupi wehutano usati watora HPMC.

Mhedziso

Hydroxypropyl methylcellulose (HPMC) inoshandiswa zvakanyanya polymeric zvinhu mumaindasitiri ezvekudya, emishonga, uye zvekuzora. Iyo yakawanikwa iine zvingangoita maapplication mukurasikirwa nehuremu, sezvo ichitendwa kuumba chipingamupinyi chemuviri mudumbu uye kuderedza kutorwa kwemafuta nemacarbohydrates. Zvidzidzo zvakawanda zvekiriniki zvakaongorora mhedzisiro yeHPMC pakurasikirwa nehuremu, uye mhedzisiro yanga ichivimbisa. HPMC inowanzoonekwa seyakachengetedzeka kuti ishandiswe nevanhu, kunyangwe inogona kudyidzana nemimwe mishonga.