HPMC yeMushonga

HPMCzvemushongayave imwe yehuwandu hukuru hwehutano uyemishonga excipients kumba uye kunze, nokuti HPMC yemishonga ine zvakanakira izvo vamwe excipients havana.

1. Kunyungudika kwemvura

HPMC yemushonga inonyungudika mumvura inotonhora iri pasi pe40 ℃ kana 70% ethanol. Iyo haina kunyungudika mumvura inopisa inopfuura 60 ℃, asi inogona kugadzirwa.

2. Chemical inertia

HPMC yemushonga ndeye isiri-ionic cellulose ether, mhinduro yayo haina ionic charge uye simbi munyu kana ionic organic compounds, saka mukugadzirira kwekugadzirwa kwemaitiro, zvimwe zvinokonzeresa hazviiti nazvo.

3. Kugadzikana

Iyo yakagadzikana kune ese acid uye base, uye inogona kuchengetwa muhuwandu hwePH 3 ~ 11 kwenguva yakareba pasina shanduko iri pachena muviscosity. HPMC aqueous solution ine mildew resistance uye inogona kuchengeta yakanaka viscosity kugadzikana mukuchengetedza kwenguva refu. Mishonga inokonzeresa kushandisa HPMC yemushonga, kugadzikana kwayo kwemhando kupfuura kushandiswa kwechinyakare excipients (senge dextrin, starch, nezvimwewo) zviri nani.

4. Adjustable viscosity

HPMC derivatives yeviscosity yakasiyana inogona kufananidzwa maererano nezvikamu zvakasiyana, viscosity yayo inogona kuchinja maererano nemimwe mitemo, uye ine hukama hwakanaka hwemutsara, saka inogona kusarudzwa maererano nezvinodiwa zvechiyero. 2. 5 metabolic inertia HPMC haina kunyura mumuviri haisi metabolized, haina kupa kupisa, saka yakachengeteka mishonga yekugadzirira excipients. .

5. Chengetedzo

HPMCzvemushongainowanzoonekwa sechinhu chisina chepfu uye chisingagumbure.

Hydroxypropyl methyl cellulose (HPMC) ndeyecelluloseether inogadzirwa nekuita kwe chloromethane uye propylene oxide ine basic cellulose. Ichena kana inenge chena fiber kana granular poda, isinganhuhwi. Yakashandiswa muindasitiri yemishonga kweanopfuura makore makumi mana, uye yakagamuchirwa muUSP19 edition uye Chinese Pharmacopoeia 1990 edition. Iyo yakawana mhedzisiro yakanaka mufirimu yekupfekedza zvinhu uye inonamira application.

Pharmaceutical giredhiHPMChydroxypropyl methyl cellulose ine zvakakwirira zvinodikanwa pane zvigadzirwa, tekinoroji yekugadzira uye mhando yechigadzirwa. Mumakore achangopfuura, pasi pesimba rekuwedzera kuomarara kwekuchengetedza nharaunda, mamwe madiki emishonga ekubatsira zvinhu mabhizinesi muEast China akatobuda pamusika, uye giredhi remishonga.HPMChydroxypropyl methyl cellulosezvemushongaindasitiri yakakanganiswawo, imwe diki-diki yekugadzira yakadzikira, uye huwandu hwehuwandu hwakagadziridzwa.