HPMC yeFirimu Coating

HPMC yeFirimu kuunganidza ndekwekutonga kwekugadzira firimu rakatetepa remurimi pamusoro pekugadzirira kwakasimba. Semuenzaniso, denderedzwa renzvimbo dzakatsiga polymer rinopfirwa zvakafanana pane pamusoro pepepa rePlay nekupuruzira nzira yekuumba mapurasitiki mafirimu akati wandei, kuitira kuti uwane maitiro anodikanwa. Kuumbwa kweiyi dhizaini yefirimu kunze kwehwendefa iri iyo piritsi imwe inoenderana nePolymer inobatanidza zvinhu mushure mekuputika, uye wozogashira chikamu chinotevera chekuvhara zvinhu mushure mekuoma. Mushure mekudzokororwa kuomarara uye kuoma, kuunganidzwa kunopedzwa kusvikira iyo nzvimbo yekugadzirira yakazara yakazara. Firimu coating firimu rinopfuurira, ukobvu zvakanyanya pakati pemasere kusvika gumi emakroni, imwe mwero wekukasira uye kushanduka, kuomerera kune iyo yepedyo.

Muna 1954, Abbhoteti akagadzira iyo yekutanga batch yemashizha emitambo, kubva ipapo, nekuvandudzwa kwemidziyo yekugadzira uye kuchinjika Kwete chete akasiyana-siyana uye mhando yemavara anowedzera vamiririri vakawedzera nekukurumidza, asiwo marudzi, mafomu ekubatanidza tekinoroji, inobatanidza midziyo yekubatanidza pamwe nekuvhara kwemapiritsi eTCM kwave kugadzirwa kwazvo. Naizvozvo, kushandiswa kwefirimu kuunganidza tekinoroji kwave kudiwa uye nekuvandudza maitiro emishonga yemishonga yekuvandudza kugadzirwa kwechigadzirwa.

Kushandiswa kwekutanga mufirimu kuunganidza mafirimu ekugadzira zvinhu, pachine huwandu hukuru hwezvigadzirwa uchishandisa HPMChydroxypruppropyl methylcelloseseMembrane zvinhu. Iko kucheneswaHpccellulose from cotton lint or wood pulp, and sodium hydroxide solution to reflect the swelling of the alkali cellulose, and then with chloromethane and propylene oxide treatment to get methyl hydroxypropyl cellulose etherHpc, chigadzirwa chekubvisa tsvina mushure mekuoma, kupwanya, kurongedza. Kazhinji, yakaderera viscosity HPMC inoshandiswa sefirimuKubatanidza zvinhu, uye 2% ~ 10% mhinduro inoshandiswa sekugadzirisa mhinduro. Iko kukanganisa ndeyekuti viscosity yakakura uye kuwedzera kwakasimba.

Chizvarwa chechipiri chefirimu kugadzira zvinyorwa ndeyePolyvinyl doro (PVA). Polyvinyl doro rinoumbwa neLalopolysis yePolyvinyl acetate. Vinyl doro rinodzokorora zvikamu hazvishandiswe sevanoita nekuti havasangane nehuwandu uye kuchena kunodiwa polymerization. Mu methanol, ethanol kana ethanol uye methyl acetate mhinduro yakasanganiswa neAlkali simbi kana inorganic acid secatlyst, hydrolysis inokurumidza.

PVA iri kushandiswa zvakanyanya mufirimu yekuvhara. Nekuti haina kujekesa mumvura pamhepo tembiricha yemakamuri, inowanzo kuunganidzwa ne 20% mvura yekupararira. Iyo Mvura yemvura uye okisijeni premeability yePVA yakaderera pane hpmc uye ec, saka kugona kwekuvhara kwemvura yemvura uye oksijeni yakasimba, iyo inogona kudzivirira chip core.

Plasticzezer inoreva zvinhu zvinogona kuwedzera plasticity yemifirimu yekuumba zvinhu. Mimwe yemafirimu ekuumba zvinhu zvinoshandura zvivakwa zvavo mushure mekunge tembiricha adzikiswe, uye kufamba kweMacromoleculu vashoma, vachiita kuti kuunganidzira kwakaoma uye kuchinjika, uye nekudaro kuputsa. Plasticzer yakawedzerwa kuti ideredze girazi transition tembiricha (tg) uye kuwedzera kuunganidza shanduko. Inowanzo shandiswa mapurasitiki ndeye Amorphous polymers ine yakakura molecular uremu uye yakasimba kubatana ine mafirimu-ekuumba zvinhu. Iyo isina kusimba plasticze inobatsira kuderedza kufarikanya kwekubatira, nekudaro inowedzera kugadzikana kwekugadzirira.

Zvinowanzoda kuti maitiro apurasitiki iya yeplasticzer mamalecules yakanyorwa mumaketeni ePolymer, ayo anovhara kuwirirana pakati pemamorita emolymer kusvika pamwero mukuru. Kubatanidzwa kuri nyore kana polymer-yeplasticzer yekudyidzana yakasimba kupfuura iyo polymer-yeplasticzer yekudyidzana. Nekudaro, mikana yemhuka dzePolymer kuti ifambe dzinowedzerwa.

Chizvarwa chechitatu chefirimu ekugadzira mafirimu ekugadzira iyo plticisder nemakemikari nzira yakarongedzwa mufirimu kuumba mari polymer

Semuenzaniso, firimu rinokurudzira kuumba zvinhu Kollicoat ® Ir rakaziviswa neBasf's Cemicy rakabatanidzwa kune imwe nguva yakareba yePeva Polymer pasina kuwedzera iyo Plondezer, saka inogona kudzivisa kutama kwegungwa mushure mekutama