Cellulose ethers ikirasi yakakosha yemapolymer macomputer ayo anoshandiswa zvakanyanya mukuvaka, machira, mishonga yemishonga nemimwe minda. Yayo yakasarudzika kemikari chimiro uye yemuviri zvimiro zvinoipa yakakosha mabhenefiti mukuvandudza adhesion uye firimu-kugadzira zvimiro.
1. Zvinhu zvakakosha zve cellulose ethers
Cellulose ether imhando yepolymer inonyungudika nemvura inowanikwa nekugadziriswa kwemakemikari echisikigo cellulose. Chimiro chayo chikuru ndeye macromolecular chain inoumbwa ne-β-D-glucose units yakabatana ne-β-1,4-glycosidic bonds. Common cellulose ethers dzinosanganisira hydroxypropyl methylcellulose (HPMC), methylcellulose (MC), carboxymethylcellulose (CMC), etc. Cellulose ethers vane kunaka kwakanaka, kuchengetedza mvura, kugadzikana, kugadzira firimu uye zvimwe zvinhu, izvo zvinoita kuti vaite basa rinokosha mukushandiswa kwakasiyana-siyana. .
2. Mechanism yekuvandudza kunamatira
Wedzera kunamatira kwemukati: Cellulose ether inogona kugadzira yakagadzikana colloidal mhinduro mune mhinduro. Iyi colloidal mhinduro inogona kugovaniswa zvakaenzana pamusoro peiyo substrate, zadza pamusoro micropores, uye kunatsiridza interfacial adhesion. Semuenzaniso, kuwedzera HPMC kuzvinhu zvekuvaka kunogona kuvandudza kunamatira pakati pedhaka uye nehwaro zvinhu, zvichiita kuti dhaka rinamatire zvakanyanya kumadziro emadziro.
Kuvandudza kunyorova kweiyo substrate pamusoro: Cellulose ether ine yakanaka hydrophilicity uye inogona kuvandudza kunyorova kwemhinduro pane substrate pamusoro, nekudaro ichiwedzera kunamatira. Wettability ndechimwe chezvinhu zvakakosha zvinokanganisa kunamatira. Nekuvandudza kunyorova, cellulose ethers inogona kusimudzira iyo yekubikira kuti inyorovese uye kuvhara iyo substrate pamusoro.
Kuvandudza mechanical embedding: Iyo firimu inoumbwa ne cellulose ether panguva yekuomesa ine imwe dhigirii yekuchinjika uye simba, iyo inobvumira cellulose ether kuumba mechanical embedding pamusoro peiyo substrate kuti iwedzere kunamatira. Iyi mechanical interlocking effect inonyanya kukosha mukuputira uye kunamatira, iyo inogona kunyatso kuvandudza maitiro ekunamatira kwezvinhu.
3. Mechanism yekuvandudza firimu-kugadzira zvinhu
Yakanakisa mafirimu ekugadzira zvinhu: Cellulose ether inogona kuumba yunifomu yakakwirira-viscosity mhinduro mushure mekunyungudika mumvura, uye inogona kuumba inoenderera yakajeka firimu mushure mekuoma. Iyi firimu ine simba rakanaka remagetsi uye kushanduka, inogona kunyatsovhara pamusoro pe substrate uye inovandudza firimu-kugadzira zvinhu. Mukuputira uye mishonga yemishonga, iyo firimu-inogadzira zvinhu zve cellulose ethers inonyanya kukosha.
Kuchengetwa kwemvura kwakanaka: Cellulose ether ine mvura yakakosha yekuchengetedza, iyo inogona kuchengetedza unyoro hwakakodzera panguva yekugadzira firimu uye kudzivirira kukanganisa kwekugadzira mafirimu kunokonzerwa nekuoma kwakanyanya. Kuchengetedza mvura kunobatsira kuumba yunifomu uye dense film layer, kudzivirira kuputika uye kuputika kwefirimu. Mukugadzira madhaka uye majasi, iyo inochengetedza mvura ye cellulose ethers inogona kuvandudza zvakanyanya kuvakwa kwekuita kwezvigadzirwa uye yekupedzisira firimu-kuumba mhando.
Dzora kumhanya kwekuomesa: Cellulose ether inogona kugadzirisa chiyero chekubuda kwemvura panguva yekugadzira firimu, zvichiita kuti firimu rekugadzira riwedzere kudzoreka. Nokudzora kukurumidza kuoma, cellulose ether inogona kudzivirira kushushikana kwepfungwa kunokonzerwa nekukurumidza kuomeswa kwefirimu layer, nokudaro kuvandudza kunaka uye kugadzikana kwefirimu. Muindasitiri yemishonga, cellulose ethers inowanzoshandiswa pakuputira zvinodhaka, izvo zvinogona kunyatso kudzora kumhanya kwekuomeswa kweiyo yekuputira layer uye kuve nechokwadi chekufanana uye kutendeseka kweiyo coating layer.
4. Mienzaniso yekushandisa
Dura rekuvaka: Kuwedzera HPMC kune dhaka rekuvaka kunogona kuvandudza zvakanyanya kunamatira uye kuita kwekuvaka kwedhaka. Kuburikidza nekuita kwayo kukora uye kuchengetedza mvura, HPMC inonatsiridza kubatanidzwa kwekubatanidza pakati pedhaka uye nheyo yezvinhu, uye inovandudza iyo firimu-inogadzira zvimiro zvedhaka, zvichiita kuti dhaka rive rakatsetseka panguva yekuvaka uye yakasimba mushure mekugadzirwa kwefirimu.
Paint: Kuwedzera cellulose ether kumvura-based pendi inogona kuvandudza kuenzana uye firimu-kuumba zvimiro zvepende, zvichiita kuti kupfekedzwa kuve kwakapfava uye kupfava. Kuburikidza neayo emhando yepamusoro yekugadzira firimu uye kuchengetwa kwemvura, cellulose ether inova nechokwadi chekuti coating inoumba dense uye yunifomu yefirimu layer panguva yekuomeswa, inovandudza kunamatira uye kusimba kwejasi.
Pharmaceutical coating: Muchirongwa chekugadzira mishonga, cellulose ethers senge HPMC inowanzo shandiswa kugadzira iyo yekuputira layer. Iyo yakanaka firimu-inogadzira zvinhu zve cellulose ether uye kugona kudzora kukurumidza kuomeswa kunogona kuve nechokwadi chekufanana uye kutendeseka kweiyo yekuputira layer uye kugadzirisa kugadzikana uye kuburitsa maitiro emushonga.
Cellulose ether ine mhedzisiro yakakosha mukuvandudza kunamatira uye firimu-kugadzira zvinhu kuburikidza nekukora kwayo, kuchengetedza mvura, uye firimu-kugadzira zvinhu. Kushandiswa kwayo kwakakura mukuvaka, machira, mishonga yemishonga uye mamwe minda inoratidza zvizere basa rayo rakakosha mukusimudzira adhesion uye firimu-kugadzira zvivakwa. Mune ramangwana, nekuenderera mberi kwekuvandudza tekinoroji yekugadzira cellulose ether uye kuvandudzwa kwezvigadzirwa zvitsva zve cellulose ether, cellulose ether icharatidza tarisiro yakakura yekushandisa mune mamwe minda.
Nguva yekutumira: Jul-13-2024