Mhedzisiro yeTembiricha pane Rheological Properties yeHydroxypropyl Methylcellulose

Hydroxypropyl methylcellulose (HPMC) isanganiswa yepolymer inonyungudika nemvura inoshandiswa zvakanyanya mumishonga, chikafu, zvekuvaka nemimwe minda. Nekuda kwekukora kwayo kwakanaka, kuumba firimu, emulsifying, bonding uye zvimwe zvivakwa, inoshandiswa zvakanyanya seyakakora, stabilizer uye inomisa mumiriri. Iyo rheological zvimiro zveHPMC, kunyanya kuita kwayo pakudziya kwakasiyana, zvinhu zvakakosha zvinokanganisa mashandisiro ayo.

1. Mhedziso yeHPMC Rheological Properties

Rheological properties inoratidzira yakazara ye deformation uye kuyerera maitiro ezvinyorwa pasi pemasimba ekunze. Kune zvinhu zvepolymer, viscosity uye shear kuonda maitiro ndiwo maviri akajairika rheological paramita. Iyo rheological properties yeHPMC inonyanya kukanganiswa nezvinhu zvakadai sema molecular weight, concentration, solvent properties uye tembiricha. Senge isiri-ionic cellulose ether, HPMC inoratidza pseudoplasticity mune aqueous solution, ndiko kuti, viscosity yayo inoderera nekuwedzera shear rate.

2. Mhedzisiro yeTemperature paHPMC Viscosity

Tembiricha ndechimwe chezvinhu zvakakosha zvinokanganisa rheological zvimiro zveHPMC. Sezvo tembiricha inowedzera, viscosity yeHPMC mhinduro inowanzodzikira. Izvi zvinodaro nekuti kuwedzera kwetembiricha kunonetesa kupindirana kwehydrogen bond pakati pemamorekuru emvura, nekudaro kudzikisa simba rekudyidzana pakati peHPMC molecular cheni, zvichiita kuti cheni dzemamorekuru dzive nyore kutsvedza nekuyerera. Naizvozvo, patembiricha yepamusoro, HPMC mhinduro dzinoratidza yakaderera viscosity.

Nekudaro, iyo viscosity shanduko yeHPMC haisi hukama hwemutsara. Kana tembiricha yakwira kusvika pamwero wakati, HPMC inogona kuita dissolution-precipitation process. Kune HPMC, hukama pakati pekunyungudika uye tembiricha yakanyanya kuomarara: mukati meimwe tembiricha renji, HPMC inonaya kubva kune mhinduro, iyo inoratidzwa sekuwedzera kwakanyanya kwemhinduro viscosity kana kuumbwa kwegel. Chiitiko ichi chinowanzoitika kana chasvika kana kudarika tembiricha yekuparara kweHPMC.

3. Mhedzisiro yekushisa pane rheological maitiro eHPMC mhinduro

Iyo rheological maitiro eHPMC mhinduro inowanzo ratidza shear-kuonda mhedzisiro, ndiko kuti, viscosity inodzikira kana shear rate ichiwedzera. Shanduko dzetembiricha dzine zvazvinoita pane iyi shear-thinning effect. Kazhinji, sezvo tembiricha inowedzera, viscosity yeHPMC mhinduro inodzikira, uye iyo shear-kutetepa mhedzisiro inova pachena. Izvi zvinoreva kuti pakupisa kwakanyanya, viscosity yeHPMC mhinduro inova inotsamira pachiyero chekugera, kureva, pachiyero chakafanana cheshear, mhinduro yeHPMC pakushisa kwepamusoro inoyerera zviri nyore pane yakaderera tembiricha.

Mukuwedzera, kuwedzera kwekushisa kunobatawo thixotropy yeHPMC solution. Thixotropy inoreva pfuma iyo viscosity yemhinduro inoderera pasi pekuita kweshear simba, uye viscosity inodzoka zvishoma nezvishoma mushure mokunge simba rekucheka rabviswa. Kazhinji, kuwedzera kwekushisa kunotungamirira kukuwedzera kwethixotropy yeHPMC solution, kureva, mushure mokunge simba rekugera rabviswa, viscosity inodzoka zvishoma nezvishoma kupfuura pasi pemamiriro ekupisa.

4. Mhedzisiro yekushisa pane gelation maitiro eHPMC

HPMC ine yakasarudzika thermal gelation pfuma, kureva, mushure mekupisa kune imwe tembiricha (gel tembiricha), iyo HPMC mhinduro ichachinja kubva kune imwe mhinduro kuenda kune gel state. Iyi nzira inonyanya kukanganiswa nekushisa. Sezvo tembiricha inowedzera, kudyidzana pakati pehydroxypropyl uye methyl substituents mumamorekuru eHPMC kunowedzera, zvichikonzera kubatanidzwa kwemacheni emamorekuru, nekudaro kugadzira gel. Ichi chiitiko chakakosha zvikuru muindasitiri yemishonga neyekudya nekuti inogona kushandiswa kugadzirisa magadzirirwo uye kuburitsa zvinhu zvechigadzirwa.

5. Kushandisa uye kukosha kunoshanda

Mhedzisiro yekushisa pane rheological properties yeHPMC inokosha zvikuru mukushanda kwekushandisa. Nekushandiswa kweHPMC mhinduro, senge gadziriro yekuregedzerwa-kuburitswa kwezvinodhaka, makobvu echikafu, kana zvigadziriso zvezvivakwa zvekuvaka, mhedzisiro yetembiricha pane rheological properties inofanirwa kutariswa kuve nechokwadi chekugadzikana uye kushanda kwechigadzirwa pasi pemamiriro ekushisa akasiyana. Semuenzaniso, kana uchigadzira zvinodhaka zvinonzwa kupisa, mhedzisiro yetembiricha inoshanduka pane viscosity uye gelation maitiro eHPMC matrix inoda kutariswa kukwirisa chiyero chekuburitsa zvinodhaka.

Tembiricha ine mhedzisiro yakakosha pane rheological properties yehydroxypropyl methylcellulose. Kuwedzera tembiricha kazhinji kunoderedza viscosity yeHPMC mhinduro, inosimudzira yayo shear-kutetepa mhedzisiro uye thixotropy, uye inogona zvakare kukurudzira kupisa kwemafuta. Mumashandisirwo anoshanda, kunzwisisa uye kudzora maitiro ekushisa pane rheological zvimiro zveHPMC ndiyo kiyi yekunatsiridza kuita kwechigadzirwa uye maitiro ekugadzirisa.