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Dissolution nzira ye (Hydroxypropyl Methyl Cellulose)HPMC

Dissolution nzira ye (Hydroxypropyl Methyl Cellulose)HPMC

Kuparara kweHydroxypropyl Methylcellulose (HPMC) kunowanzobatanidza kuparadzira hupfu hwepolymer mumvura pasi pemamiriro ezvinhu akadzora kuti ave nechokwadi chemvura uye kupera. Heino nzira yakajairika yekumisa HPMC:

Zvishandiso Zvinodiwa:

  1. HPMC hupfu
  2. Distilled kana deionized mvura (kuti zvive zvakanaka)
  3. Kusanganisa mudziyo kana mudziyo
  4. Stirrer kana kusanganisa midziyo
  5. Midziyo yekuyeresa (kana chaiyo dosing inodiwa)

Dissolution Procedure:

  1. Gadzirira Mvura: Edza huwandu hunodiwa hwemvura yakasvibiswa kana yakasvibiswa zvichienderana nehuwandu hunodiwa hweHPMC solution. Zvakakosha kushandisa mvura yemhando yepamusoro kudzivirira tsvina kana tsvina kuti isakanganise nzira yekuparara.
  2. Pisai Mvura (Zvichida): Kana zvichidiwa, pisa mvura kusvika kune tembiricha iri pakati pe20°C kusvika 40°C (68°F kusvika 104°F) kuti ifambise kuparara. Kupisa kunogona kukurumidzira hydration yeHPMC uye kunatsiridza kupararira kwepolymer zvimedu.
  3. Zvishoma nezvishoma Wedzera HPMC Powder: Zvishoma nezvishoma wedzera HPMC poda kumvura paunenge uchikurudzira nguva dzose kudzivirira clumping kana agglomeration. Zvakakosha kuwedzera hupfu zvishoma nezvishoma kuti uone kupararira kweyunifomu uye kudzivisa kuumbwa kwemapundu.
  4. Ramba Uchikurudzira: Chengetedza kubvongodza kana kubvongodza kwemusanganiswa kusvikira iyo HPMC poda yakapararira zvachose uye yakasvibiswa. Izvi zvinowanzotora maminetsi akati wandei, zvichienderana nekukura kwehupamhi hweHPMC hupfu uye nekumhanyisa kumhanya.
  5. Bvumira Hydration: Mushure mekuwedzera iyo HPMC poda, bvumira musanganiswa kuti umire kwenguva yakakwana kuti uve nechokwadi chekuzara kwepolymer. Izvi zvinogona kubva pamaminitsi makumi matatu kusvika kumaawa akati wandei, zvichienderana negiredhi chairo uye saizi yeHPMC.
  6. Gadzirisa pH (kana zvichidikanwa): Zvichienderana nekushandiswa, ungangoda kugadzirisa pH yemhinduro yeHPMC uchishandisa asidhi kana alkali mhinduro. Iyi nhanho inonyanya kukosha kune zvikumbiro apo pH senitivity yakakosha, senge mumishonga kana yemunhu kuchengetedza maumbirwo.
  7. Sefa (kana zvichidikanwa): Kana iyo HPMC mhinduro iine zvimedu zvisinganyungudika kana zvisina kunyungudika aggregates, zvingave zvakafanira kusefa mhinduro uchishandisa yakanaka mesh sieve kana sefa bepa kuti ubvise chero yakasara yakaoma.
  8. Chengetedza kana Kushandisa: Kana iyo HPMC yanyungudika zvizere uye hydrated, mhinduro yakagadzirira kushandiswa. Inogona kuchengetwa mumudziyo wakavharwa kana kushandiswa nekukasira mumashandisirwo akasiyana siyana semishonga, cosmetics, zvekuvaka, kana zvigadzirwa zvekudya.

Notes:

  • Dzivisa kushandisa mvura yakaoma kana mvura ine yakakwira mineral content, sezvo inogona kukanganisa kuparara kwemaitiro uye kuita kweHPMC mhinduro.
  • Iyo nguva yekunyungudika uye tembiricha inogona kusiyana zvichienderana negiredhi chairo, particle size, uye viscosity giredhi yeHPMC poda inoshandiswa.
  • Gara uchitevera kurudziro yemugadziri uye nhungamiro yekugadzirira HPMC mhinduro, sezvo magiredhi akasiyana anogona kunge aine zvinodiwa zvekuparara.

Nguva yekutumira: Feb-15-2024
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