Hydroxyethyl Cellulose (HEC) uye mamwe cellulose ethers (akadai sehydroxypropyl methylcellulose (HPMC), methylcellulose (MC), hydroxypropyl cellulose (HPC) uye carboxymethyl cellulose (CMC)) ma polymers anoshandiswa zvakanyanya muindasitiri, kuvaka, mushonga, chikafu uye zuva nezuva. maindasitiri emakemikari. Izvi zvinobva kune cellulose zvinogadzirwa nekemikari kushandura cellulose uye zvine mvura yakanaka solubility, thickening, kugadzikana uye firimu-forming properties.
1. Hydroxyethyl Cellulose (HEC)
1.1 Kuumbwa Kwemakemikari uye Zvivakwa
Hydroxyethyl Cellulose (HEC) inogadzirwa nehydroxyethylation ye cellulose ine ethylene oxide pasi pemamiriro ealkaline. Iyo yakakosha chimiro cheHEC chisungo cheether chinoumbwa nekutsiviwa kweboka re hydroxyl mu cellulose molecule neboka re hydroxyethyl. Ichi chimiro chinopa HEC yakasarudzika zvivakwa:
Kunyungudika kwemvura: HEC inonyungudika mumvura inotonhora uye inopisa kuti igadzire yakajeka colloidal mhinduro.
Kukora: HEC ine yakanakisa thickening zvivakwa uye inoshandiswa zvakanyanya mumaapplication anoda viscosity control.
Kugadzikana: HEC mhinduro ine kugadzikana kwakanyanya mumhando dzakasiyana dzepH.
Biocompatibility: HEC haina-chepfu, isingatsamwire, uye ine hushamwari kumuviri wemunhu uye nharaunda.
1.2 Nzvimbo dzekushandisa
Zvishandiso zvekuvaka: inoshandiswa seyakakora uye inochengetedza mvura mudhaka sesimende uye zvigadzirwa zvegypsum.
Coatings uye pendi: inoshandiswa seyakakora, inomisa mumiriri uye stabilizer.
Makemikari ezuva nezuva: anoshandiswa seanokora mune zvinodiwa zvezuva nezuva senge madhishi uye shampoos.
Pharmaceutical field: inoshandiswa seanonamira, thickener uye suspending agent yemapiritsi emishonga.
1.3 Zvakanakira uye zvazvakaipira
Zvakanakira: yakanaka solubility yemvura, kugadzikana kwemakemikari, yakafara pH kuchinjika uye isiri-chepfu.
Zvakaipa: kunyungudika kwakashata mune zvimwe zvinonyungudutsa, uye mutengo unogona kunge wakakwira zvishoma pane mamwe ma cellulose ether.
2. Kuenzanisa kwemamwe cellulose ethers
2.1 Hydroxypropyl methylcellulose (HPMC)
2.1.1 Chimiro chemakemikari uye zvivakwa
HPMC inogadzirwa kubva ku cellulose kuburikidza nemethylation uye hydroxypropylation reactions. Chimiro chayo chine zvese methoxy (-OCH3) uye hydroxypropoxy (-OCH2CH (OH) CH3) inotsiva.
Kunyungudika kwemvura: HPMC inonyungudika mumvura inotonhora kuti iite yakajeka colloidal mhinduro; haina kunyungudika kwakashata mumvura inopisa.
Kukora pfuma: Iyo ine yakanakisa gobvu kugona.
Gelling properties: Inoumba gel kana ichipisa uye inodzokera kune yayo yepakutanga kana yatonhodzwa.
2.1.2 Nzvimbo dzekushandisa
Zvishandiso zvekuvaka: Inoshandiswa seyakakora uye inochengetedza mvura mumiriri we simende-yakavakirwa uye gypsum-yakavakirwa zvinhu.
Chikafu: Inoshandiswa se emulsifier uye stabilizer.
Mushonga: Inoshandiswa sechinhu chinobatsira chemishonga capsules uye mahwendefa.
2.1.3 Zvakanakira nezvazvakaipira
Advantages: Good thickening kuita uye gelling zvinhu.
Zvakaipa: Inonzwira tembiricha uye inogona kutadza mukupisa kwakanyanya.
2.2 Methyl cellulose (MC)
2.2.1 Chimiro chemakemikari uye zvivakwa
MC inowanikwa nemethylation ye cellulose uye kunyanya ine methoxy (-OCH3) inotsiva.
Kunyungudika kwemvura: inonyungudika zvakanaka mumvura inotonhora kuita inoonekera colloidal mhinduro.
Kukora: kune yakakosha kukora mhedzisiro.
Thermal gelation: inoumba gel kana ichipisa uye degels kana yatonhodzwa.
2.2.2 Nzvimbo dzekushandisa
Zvishandiso zvekuvakisa: inoshandiswa seyakakora uye inochengeta mvura yedhaka nependi.
Chikafu: inoshandiswa se emulsifier uye stabilizer.
2.2.3 Zvakanakira nezvazvakaipira
Advantages: kwakasimba thickening kugona, kazhinji inoshandiswa mukutonhora kugadzirisa tekinoroji.
Kukanganisa: kupisa-kunzwa, hakugone kushandiswa pakupisa kwakanyanya.
2.3 Hydroxypropyl cellulose (HPC)
2.3.1 Chimiro chemakemikari uye zvivakwa
HPC inowanikwa ne hydroxypropyl cellulose. Chimiro chayo chine hydroxypropoxy (-OCH2CH(OH)CH3).
Kunyungudika kwemvura: inonyungudika mumvura inotonhora uye organic solvents.
Kukora: kuita zvakanaka kukora.
Firimu-kugadzira pfuma: inoumba firimu rakasimba.
2.3.2 Nzvimbo dzekushandisa
Mushonga: unoshandiswa sechinhu chekuputira uye piritsi rinobatsira zvinodhaka.
Chikafu: inoshandiswa se thickener uye stabilizer.
2.3.3 Zvakanakira nezvazvakaipira
Mabhenefiti: akawanda-anonyungudika solubility uye yakanakisa firimu-kugadzira pfuma.
Kukanganisa: mutengo wakakwirira.
2.4 Carboxymethyl cellulose (CMC)
2.4.1 Chimiro chemakemikari uye maitiro
CMC inogadzirwa nekuita cellulose ine chloroacetic acid, uye ine carboxymethyl boka (-CH2COOH) muchimiro chayo.
Kunyungudika kwemvura: kunyungudika mumvura inotonhora uye mvura inopisa.
Kukora pfuma: yakakosha kukora mhedzisiro.
Ionicity: ndeyeanionic cellulose ether.
2.4.2 Nzvimbo dzekushandisa
Chikafu: inoshandiswa se thickener uye stabilizer.
Makemikari ezuva nezuva: anoshandiswa semukobvu kune detergent.
Papermaking: inoshandiswa sekuwedzera kwekuputira mapepa.
2.4.3 Zvakanakira nezvazvakaipira
Advantages: yakanaka kukora uye yakakura application minda.
Kukanganisa: inonzwisisika kune electrolytes, ions mumhinduro inogona kukanganisa kushanda.
3. Kuenzanisa kwakakwana
3.1 Kuwedzera kuita
HEC uye HPMC vane yakafanana thickening kuita uye ose ane yakanaka thickening maitiro. Nekudaro, HEC ine zvirinani kunyungudika kwemvura uye inokodzera maapplication anoda kujeka uye kushomeka kushatirwa. HPMC inonyanya kubatsira mumashandisirwo anoda kudziyisa kune gel nekuda kweiyo thermogel zvivakwa.
3.2 Kunyungudika kwemvura
HEC neCMC zvinogona kunyungudutswa mumvura inotonhora uye inopisa, nepo HPMC neMC zvichinyanya kunyungudika mumvura inotonhora. HPC inosarudzwa kana multi-solvent kuenderana kunodiwa.
3.3 Mutengo uye renji yekushandisa
HEC inowanzotengeswa zvine mwero uye inoshandiswa zvakanyanya. Kunyangwe HPC iine mashandiro akanaka, inowanzo shandiswa mukudiwa kwepamusoro-soro nekuda kwekudhura kwayo. CMC ine nzvimbo mune dzakawanda-mutengo wakaderera kunyorera nemutengo wayo wakaderera uye kuita kwakanaka.
Hydroxyethyl cellulose (HEC) yave imwe yeanonyanya kushandiswa cellulose ethers nekuda kwekunaka kwayo kunyungudika kwemvura, kugadzikana uye kugona kukora. Kuenzaniswa nemamwe ma cellulose ethers, HEC ine zvimwe zvakanakira mukunyungudika kwemvura uye kugadzikana kwekemikari, uye inokodzera zvikumbiro zvinoda mhinduro dzakajeka uye yakafara pH kuchinjika. HPMC inokunda mune dzimwe nzvimbo dzakatarwa nekuda kwekukora uye nekupisa kwayo gelling zvimiro, nepo HPC neCMC vachitora chinzvimbo chakakosha mundima dzadzo dzekushandisa nekuda kwemaitiro ekugadzira firimu uye mutengo wakanaka. Zvinoenderana nezvinodiwa zvekushandisa, kusarudza iyo chaiyo cellulose ether inogona kukwidziridza kuita kwechigadzirwa uye kudhura-kushanda.
Nguva yekutumira: Jul-10-2024