CMC Yakadzora kushandiswa kwekurapa

CMC (carboxymethylcellulose) inonyungudika mumvura, anionic polymer iyo inoshandiswa zvakanyanya sechinhu chinopa muindasitiri yemishonga. Iyo inotorwa kubva ku cellulose, iyo inongoitika polysaccharide, nekuwedzera carboxymethyl mapoka kune yayo chimiro. CMC inozivikanwa nekunaka kwayo firimu-kuumba uye kukora zvimiro, zvichiita kuti ive inogoneka uye yakakosha mumidhiyo mumizhinji yemishonga.

Mumishonga yemishonga, CMC inowanzoshandiswa seyakakora, inosimbisa, uye mafuta. Seyakakora, CMC inoshandiswa mumhando dzakasiyana-siyana dzekugadzira, senge makirimu, lotions, uye gels, kupa viscosity uye kunatsiridza maitiro avo. Izvi zvinobatsira kusimudzira kugadzikana uye kuenderana kwechigadzirwa, zvichiita kuti zvive nyore kushandisa uye zvakanyanya kunakidza kune varwere kushandisa. CMC inoshandiswawo seyakagadzikana mukumiswa uye emulsions, kubatsira kudzivirira zvimedu kubva pakugadzirisa uye kuve nechokwadi chekuti chigadzirwa chinoramba chiri homogeneous. Pamusoro pezvo, CMC inoshandiswa semafuta ekuzora muhwendefa uye capsule maumbirwo, zvichibatsira kuvandudza kuyerera kwavo uye nyore kumedza.

Imwe yeanonyanya kurapa mashandisirwo eCMC ari mune ophthalmic formulations. CMC inoshandiswa mumadonhwe eziso nemisodzi yekunyepedzera kupa mafuta ekuzora uye kudzikamisa zviratidzo zvemaziso akaoma. Ziso rakawoma chinhu chinowanzoitika kana maziso asingabudisi misodzi yakakwana kana kuti misodzi ikakurumidza kubuda. Izvi zvinogona kukonzera kushatirwa, kutsvuka, uye kusagadzikana. CMC mushonga unoshanda weziso rakaoma nekuti inobatsira kuvandudza kugadzikana uye kuchengetedza nguva yekubvarura firimu pameso emeso, nekudaro kuderedza kuoma uye kutsamwa.

Pamusoro pekushandiswa kwayo mukugadzirwa kwemaziso, CMC inoshandiswawo mune mimwe mishonga yemuromo kuvandudza kunyungudika kwayo uye kuparara kwehuwandu. CMC inogona kushandiswa se disintegrant mumapiritsi, ichivabatsira kuputsa nekukurumidza mudumbu remukati uye kuvandudza bioavailability yechinhu chinoshanda. CMC inogona zvakare kushandiswa sebhainda muhwendefa uye capsule maumbirwo, zvichibatsira kubata zvinoshanda zvinosanganisa pamwechete nekuvandudza kusimba kwavo.

CMC inogamuchirwa nevakawanda muindasitiri yemishonga uye inodzorwa neakasiyana siyana anodzora zvinodhaka pasi rese. MuUnited States, FDA (Food and Drug Administration) inoronga CMC sechikafu chekuwedzera uye sechinhu chisingaiti mumishonga. Iyo FDA yakagadzira zvakatemwa zvemhando uye kuchena kweCMC inoshandiswa mumishonga uye yakaisa mazinga epamusoro etsvina uye zvakasara zvinonyungudutsa.

MuEuropean Union, CMC inodzorwa neEuropean Pharmacopoeia (Ph. Eur.) uye inosanganisirwa mune rondedzero yezvinobatsira zvinogona kushandiswa mumishonga yemishonga. Iyo Ph. Eur. yakagadzirawo zvirevo zvemhando uye kuchena kweCMC inoshandiswa mumishonga, kusanganisira miganhu yetsvina, simbi inorema, uye zvakasara zvinonyungudutsa.

Pakazere, CMC inoita basa rakakosha mune akawanda emishonga mafomati uye inoshandiswa mumhando dzakasiyana dzekurapa. Kunaka kwayo kukora, kudzikamisa, uye kudzosa zvimiro kunoita kuti ive inogoneka inogonesa iyo inogona kushandiswa muhuwandu hwakasiyana hwekuumbwa. Sechinhu chinogadziriswa, makambani emishonga anogona kuvimba neCMC kuti ive yakachengeteka, inoshanda, uye yemhando yepamusoro mumagadzirirwo awo.