Muamua, o le faapuupuuga faaPeretania o mea ausilali
MC: Methyl cellulose
EC: ethyl cellulose
HPC: hydroxypropyl cellulose
HPMC: hydroxypropyl methylcellulose
CAP: Cellulose acetate phthalates
HPMCP: hydroxypropyl cellulose phthalates
HPMCAS: hydroxypropyl methyl cellulose acetate succinate
Cmc-na: Sodium carboxymethyl cellulose
MCC: Microcrystalline cellulose
PVP: Povidone
PEG: polyethylene glycol
PVA: Polyvinyl alcohol
Cms-na: Sodium carboxymethyl starch
PVPP: Povidone feso'ota'i
CCNa: fa'afeso'ota'i le sodium carboxymethyl cellulose
Lua, o le faʻaaogaina o nisi mea fesoasoani
1. Lactose: laulau: fa'atumu, aemaise lava le pa'u sa'o le fa'atumu o laulau; tui: lyophilized puipuiga
2. Microcrystalline cellulose: laulau: pa'u sa'o oomi laulau faatumu; “Fa'apipi'i mago”; Papama'a o lo'o i ai le 20% microcrystalline cellulose e galue e pei o ni fa'amavae
3. Methyl cellulose: laulau: pipii; Sui fa'amalolo: fesoasoani fa'amalolo; Sauniuniga lemu (pulea) fa'asa'oloto: mea auivi gel hydrophilic (vaivai)
4 sodium carboxymethyl cellulose: papa: pipii; Sui fa'amalolo: fesoasoani fa'amalolo; Sauniuniga lemu (pulea) fa'asa'oloto: mea auivi gel hydrophilic
5. Ethyl cellulose: laulau: fa'apipi'i (e le mafai ona fa'afefe i le vai); Sauniuniga lemu (pulea) fa'asa'oloto: mea auivi po'o mea e fa'atonutonuina; Fa'asalalau solo: mea e feavea'i e le mafai ona solu
6 hydroxypropyl cellulose: laulau: fa'apipi'i, mea e ufiufi ai ata; Sui fa'amalolo: fesoasoani fa'amalolo; Sauniuniga lemu (pulea) fa'asa'oloto: mea auivi gel hydrophilic, microporous membrane fa'apipi'i le laupepa pore-inducing agent
7. Hydroxypropyl methyl cellulose (hydroxypropyl methyl cellulose): papa: faʻapipiʻi, mea faʻapipiʻi ata; Sui fa'amalolo: fesoasoani fa'amalolo; Sauniuniga fa'asa'oloto fa'agesegese ma fa'atonutonuina: mea fa'a'au'au gel hydrophilic, mea fa'apipi'i pupuni fa'apipi'i fa'apipi'i microporous.
8. Cellulose acetate phthalates: mea enteric
9. Hydroxypropyl cellulose phthalates: mea fa'aoga
10. Hydroxypropyl cellulose acetate succinate: mea fa'aoga
11. Polyvinyl phthalate (PVAP): mea fa'aoga
12. Styrene Maleic acid copolymer (StyMA): mea e solu le intestinal
13. resini akrilic (ituaiga enteric I, II, III), Eudragit L, Eudragit S (o nisi taimi Eudragit L100 po o Eudragit S 100): mea enteric
14.Eudragit RL, Eudragit RS: : Mea e feavea'i e le mafai ona solu
15.Eudragit E (tutusa ma acrylic IV): gastric soluble mea polymer
16. Cellulose acetate: vai mea e le mafai ona solu, e mafai ona faʻaogaina mo le faʻapipiʻiina poʻo le saunia o papa pamu osmotic.
17. Polyvinylpyrrolidone (povidone PVP): papa: faʻapipiʻi; Laupapa: gastric soluble mea e ufiufi ata; Pellets: pellets nifedipine (fa'asalalau malo); Sui fa'amalolo: fesoasoani fa'amalolo;
Fa'asalalau solo: mea e ave ai le vai-soluble; Sauniuniga lemu (pulea) fa'asa'oloto: mea auivi colloid hydrophilic; Sauniuniga lemu (pulea) fa'asa'oloto: so'o fa'aoso-po i totonu o papama'a fa'apipi'i le microporous
18. Polyvinyl alcohol: sui o ata tifaga: mea e fai ai ata, fesoasoani taofi
19. Sodium carboxymethyl starch: laulau: fa'ama'i
20. Povidone feso'ota'i: Laupapa: fa'ama'i
21. Sosaisa carboxymethyl cellulose feso'ota'i feso'ota'i: laulau: so'o fa'ama'i
22. E maualalo le suia o le hydroxypropyl cellulose: Papamaa: fa'ama'i
23. Polylactic acid: mea polymer biodegradable, faʻaaogaina mo le saunia o microspheres, nanoparticles, ma isi.
24. Glycerol (sorbitol propylene glycol e sili atu ona vavalalata i le glycerol)
Sauniuniga vai: solvent, solvent tui, fesoasoani taofi, moisturizer
Plasticizer i capsule ma mea faʻapipiʻi
Su'u suauu, faiga tu'uina atu transdermal: fa'aoso fa'aoso
Faʻateleina le susu o vailaʻau hydrophobic, osmotic pressure regulator i totonu ole gaʻo emulsion.
Glycerin gelatin (mo suauu, suppositories, faʻasalalau solo)
25. Glycerin gelatin
Pa'u fuala'au: matrix solu vai
Supository: matrix solu vai
Su'u: Suavai soluble matrix
26. Sodium dodecyl sulfate
Emulsions, suauu: emulsifiers
Su'e susū mo tapenaga malosi/lubricant mo papa
solubilizer
27. Polyethylene glycol (PEG)
Papamaa: Suavai-soluble lubricant (PEG 4000, 6000)
Laupapa: Fa'apipi'i i totonu o fa'atonuga fa'apipi'i ata
Capsule: Kapisi vaivai e le o le ga'o vai (PEG 400)
Fua'i fa'apa'u: fa'ama'i fa'asuavai (PEG 4000, 6000,9300)
Supository: suppository matrix
Aerosol: Latent solvent (PEG 400, 600)
Tuiina: Solvent (PEG 400, 600)
Suavai tapenaga: Solvent (PEG 400, 600)
Fa'asalalau solo: ave
Sauniuniga lemu (pulea) fa'asa'oloto: so'o fa'aoso-po i totonu o papama'a fa'apipi'i le microporous
Sauniuniga mo le fa'a'ai ile pa'u: transdermal absorption enhancer
28. Poloxam (” zwitterionic “surfactant) Na matauina e se uo ma le faaeteete se eseesega iinei, o lea ua faasa'oina i le” Poloxam “non-ionic surfactant, ae le o le zwitterionic surfactant!
Va'a fa'asalalau solo, suppository matrix, emulsifier mo tui po'o fa'afu
O se aotelega o vailaʻau faʻamaʻi ma bacteriostatic
Hydroxyl benzene ester (neper auro), benzoic acid, sodium benzoate, sorbic acid, benzalkonium bromide (fa'amama fou), benzalkonium chloride (jie er die), chlorhexidine acetate, benzyl alcohol (tiga i le lotoifale) i le taimi lava e tasi, feso'ota'i feso'ota'i. fa'atasi ai ma le 'ava malosi fa'apitoa (tiga fa'apitonu'u) i le taimi e tasi, nitrobenzene, mercury, thimerosal, fa'ama'i fa'ama'i, ortho-phenyl phenol, phenoxyethanol, suau'u eucalyptus, suau'u kinnamon, suau'u pepa, ma isi.
Fa, faiga fa'ama'i
1/ tui kulukose, emulsion ga'o mo tui tui, dextran, infusion sodium chloride, pa'u pa'u ma isi sterilization oomi vevela;
2/ Vaitamini C tui, procaine hydrochloride tui, cortisone acetate tui, chloramphenicol mata mataua na sterilized e ala i le ausa feaveai;
3/ Suau'u tui, ga'o matrix, ampoule e fa'aaoga ai le fa'amamago vevela auala fa'amago;
4/ Asepsis potu ea, fa'agaoioi luga laulau: auala ultraviolet sterilization po'o auala fumigation kasa;
5/ Lima, meafaigaluega fa'a'eseptic: metotia fa'ama'i fa'ama'i
6/ Insulin tui ma isi mea ola: filtration sterilization auala
V. Fa'atatau tutusa
1. Noyes-whitney equation: o loʻo faʻamatalaina ai le faʻamavaeina o vailaʻau malosi.
2. Susū fa'atusatusa mata'utia o le paluga
hygroscopicity ole pa'u P68)
3. Suiga tausupository P87)
4. Poiseuile fua fa'atatau: fa'amatala mea e a'afia ai le filtration (tui P124)
5. Fuafuaga fa'atatau o le fa'atonuina o le isotonic e ala i le fa'a'aisa o le fa'alaloina o le togitui P156)
6. Fa'atatauina ole tau ole HLB ole sufa fa'afefiloivai P178)
Tekinolosi sauniuni talafeagai
1. Microcapsule: auala condensation (tasi, lavelave), solvent-non-solvent auala, suiga o le vevela auala, auala faʻagogo vai, auala faʻagogo faʻagogo, auala faʻafefeteina, auala faʻafefeteina, auala faʻafefete faʻafesoʻotaʻi, auala crosslinking radiation
2. Fa'aaofia fa'aputuga: auala fa'asusu vaifofo, auala olo, fa'a'aisa auala fa'agogo, fa'amamago auala.
3. Faʻasalalau solo: auala faʻafefete, auala faʻafefe, solvent - faʻafefeteina auala, solvent - faʻagogo auala faʻagogo, auala olo
4. Liposomes: auala tui, faʻataʻapeʻapeina ata manifinifi, auala faʻasalalau ultrasonic, auala faʻafefete faʻafefe, auala faʻagogo aisa
5. Microspheres: emulsification - auala faʻamalolo, auala faʻamagoina, auala faʻagogo vai
6. Nanoparticles: polymerization micellar, polymerization emulsion, polymerization interfacial, auala faʻagogo vai
7. Pellet: faʻapupuna auala faʻapipiʻi, faʻapipiʻi auala faʻapipiʻi, auala faʻapipiʻi ipu, auala faʻapipiʻi sphericity, auala centrifugal projectile, auala faʻagogo vai.
8 suppository: auala vevela vevela, auala oomi malulu, lomi auala
9. Suauu: auala olo, faʻafefeteina auala, auala emulsification
10 sui o ata tifaga: homogenized slurry tafe ata faiga faiga, uunaiga-liusua ata faiga faiga, tuufaatasia ata faiga faiga
Fitu, mea fa'atusa
1. Microcapsule: gelatin - Alapi gum
2. Fa'aopoopo fa'atasi: cyclodextrin
3. Fa'asalalau solo: PEG, PVP
4. Liposomes: phospholipid-cholesterol
5. Microspheres: gelatin, albumin, PLA, ma isi
6. Supository: pata koko
7. Su'u su'u: Suauu suau'u, ma isi
8 sui o ata tifaga: PVA
Valu, o ni nai taimi
1. O le ampoule sterilized e tatau ona tuʻu mo le sili atu i le 24 itula;
2. Teuina o vai mo tui e le tatau ona sili atu i le 12 itula;
3. E tatau ona fa'amae'aina le fa'amama o tui fa'ato'a i totonu ole 12 itula talu ona tu'u ipu;
4. Infusion ma fofo saunia e tatau ona maeʻa i totonu ole 4 itula ole faʻamaʻi
9. Su'esu'ega lelei mea e feso'ota'i ma tapenaga tau vaila'au
1. Papamaa: foliga vaaia; Eseesega mamafa tipi; Malosi ma le pala; Fa'ailoga fa'aletonu; Fa'amavae pe fa'asa'oloto; Tulaga tutusa o anotusi
2. Fa'asalalauina sui: tutusa; Susū. Utaina le tele o eseesega; Su'ega ole soifua maloloina; Su'esu'ega fa'apitoa
3. Granule: foliga vaaia; Lapopo'a; pa'u mamafa mamago; liusuavai; Le eseesega o uta
4. Capsule: foliga vaaia; Susū. Utaina le tele o eseesega; Ta'ape ma fa'amavae.
5. Pa'u fualaau: eseesega o le mamafa; Su'ega taimi fa'atapula'aina, ma isi.
6. Suppository: foliga vaaia; Eseesega i le mamafa; Taimi fa'afefeteina; Va'aiga fa'afefeteina; Su'ega fa'amuta fa'atasi ma su'esu'ega fa'asusu i vivo
7. Faila: lapopo'a; O le uta; tapulaa microbial; mea autu o fualaau faasaina; Meatotino faaletino; Fa'aosofia; Maumau; Faʻasaʻo, faʻaogaina ma le faʻaogaina o vailaʻau i totonu o le suauu.
8. Transdermal patch: eseesega mamafa; Eseesega vaega; Tulaga tutusa o anotusi; Fa'asa'oloto tikeri, ma isi.
10. Faauigaga eseese
1. Micro capsule: o se tamai capsule e fausia e ala i le afifiina o se vailaʻau malosi poʻo se vai (ua taʻua o le capsule core) i se mea faʻapitoa poʻo se mea faʻapipiʻi polymer (taʻua o mea capsule). 1-5000 microns
2. Pellet: e faasino i le vaega lapotopoto ma le lautele e itiiti ifo i le 2.5mm e aofia ai fualaau faasaina ma mea aoga.
3. Microsphere: o se skeleton-type microscopic spherical spherical e fausia e ala i le faʻamavaeina poʻo le faʻasalalau vailaʻau i totonu o le faʻavae o mea polymer, faʻatasi ai ma se lapopoa e masani lava i le va o le 1 ma le 250μm.
4. Nanoparticles: vaega colloidal malosi e aofia ai mea polymeric, faatasi ai ma le tele o vaega i le va o le 10 ~ 1000nm.
5. Fa'apa'u pili fualaau: e fa'atatau i vaila'au mafiafia po'o vai ma mea talafeagai (e masani ona ta'ua o le matrix) fa'afefiloi fa'afefete fa'amafanafana, pa'u i le condensate miscible, condensation fa'aiti'itia ma faia i ni tapenaga pellet laiti.
Taimi meli: Sep-09-2022