Niki HPMC polymer

Hydroxypropyl Methylcellulose (HPMC) ni polymer ikoreshwa cyane hamwe nibikorwa bitandukanye mubikorwa bitandukanye, harimo imiti, ibiryo, ubwubatsi, hamwe no kwisiga. Uru ruganda rwinshi rufite ibintu byihariye bituma bigira agaciro muburyo butandukanye.

1. Imiterere n'imiterere

1.1 Imiterere ya molekulari: HPMC ni polymeris semisintetike polymer ikomoka kuri selile, ikaba ari biopolymer nyinshi kwisi. Ikorwa hifashishijwe uburyo bwo guhindura imiti ya selile, cyane cyane kuyivura hamwe na oxyde ya propylene na methyl chloride kugirango itangize hydroxypropyl na methyl.

1.2 Ibyiza bifatika: HPMC mubisanzwe iboneka nkifu yera cyangwa yera. Ntabwo ari impumuro nziza, uburyohe, kandi ntabwo ari uburozi, bigatuma itekera gukoreshwa mubikorwa bitandukanye. Ubushobozi bwa HPMC buterwa nibintu nkuburemere bwa molekile, urugero rwo gusimburwa, nubushyuhe. Irerekana ibintu byiza cyane byerekana firime kandi irashobora gukora firime ibonerana iyo ishonga mumazi.

1.3 Ibyiza bya Rheologiya: Ibisubizo bya HPMC byerekana imyitwarire ya pseudoplastique, bivuze ko ububobere bwabo bugabanuka hamwe no kongera umuvuduko wogosha. Uyu mutungo ufite akamaro mubisabwa nka coatings, aho byoroshye gusaba no kuringaniza.

2. Synthesis

Synthesis ya HPMC ikubiyemo intambwe nyinshi. Ubwa mbere, selile isanzwe iboneka mubiti cyangwa ibiti by'ipamba. Hanyuma, ihura na etherification hamwe na okiside ya propylene na methyl chloride mugihe cyagenwe kugirango itangize hydroxypropyl na methyl mumatsinda ya selile. Urwego rwo gusimbuza (DS) rwaya matsinda rushobora guhindurwa kugirango uhuze imitungo ya HPMC yavuyemo kubisabwa byihariye.

3. Porogaramu

3.1 Imiti: HPMC ikoreshwa cyane mubikorwa bya farumasi bitewe na biocompatibilité, imitungo ya mucoadhesive, hamwe nubushobozi bwo kurekura. Irakoreshwa cyane nka binder, firime yahoze, idahwitse, kandi ikomeza-kurekura ibintu muburyo bwa tablet. Byongeye kandi, HPMC ishingiye kuri gel ikoreshwa mugutegura amaso kugirango yongere igihe cyo gutura ibiyobyabwenge hejuru ya ocular.

3.2 Inganda zibiribwa: Mu nganda zibiribwa, HPMC ikoreshwa nkumubyimba, stabilisateur, emulisiferi, hamwe nububiko bwo kubika neza. Bikunze kuboneka mubikomoka ku mata, ibicuruzwa bitetse, amasosi, n'ibinyobwa. HPMC ifasha kunoza imiterere, ituze, hamwe numunwa wibicuruzwa byibiribwa udahinduye uburyohe cyangwa agaciro kintungamubiri.

3.3 Ibikoresho byubwubatsi: HPMC ningingo yingenzi mubikoresho byubwubatsi nka minisiteri ishingiye kuri sima, gushushanya, hamwe na tile. Ikora nkibikoresho byo kubika amazi, itezimbere imikorere, igabanya kugabanuka, kandi ikongerera guhuza ibyo bikoresho kubutaka. HPMC ishingiye kuri minisiteri yerekana uburyo bwiza bwo guhangana no gucika no kugabanuka, biganisha ku nyubako ziramba kandi zishimishije.

3.4 Amavuta yo kwisiga: Mu nganda zo kwisiga, HPMC ikoreshwa muburyo butandukanye, harimo amavuta, amavuta yo kwisiga, geles, na mascara. Ikora nk'ibyimbye, emulifisiyeri, stabilisateur, na firime yahoze muri ibyo bicuruzwa. HPMC itanga imiterere yamagambo ya rheologiya, yongerera ubwiza, kandi itanga ingaruka zirambye muburyo bwo kwisiga.

4. Ibizaza

Biteganijwe ko icyifuzo cya HPMC kizakomeza kwiyongera mu myaka iri imbere, bitewe no kwagura imiti mu miti, ibiryo, ubwubatsi, no kwisiga. Imbaraga zubushakashatsi zikomeje kwibanda mugutezimbere ibishya no kunoza imikorere yibicuruzwa bihari. Iterambere muri nanotehnologiya rishobora kuganisha ku iterambere rya nanocomposite ishingiye kuri HPMC hamwe n’imiterere y’imashini, ubushyuhe, na barrière, byugurura amahirwe mashya mu nganda zitandukanye.

Hydroxypropyl Methylcellulose (HPMC) ni polymer itandukanye kandi ifite uburyo bwinshi bwo gukoresha mubikorwa bitandukanye. Ihuza ryihariye ryimiterere, harimo biocompatibilité, kugenzura rheologiya, hamwe nubushobozi bwo gukora firime, bituma iba ingenzi muri farumasi, ibiryo, ubwubatsi, no kwisiga. Hamwe nubushakashatsi niterambere bikomeje, HPMC yiteguye gukomeza kuba ingenzi muburyo butandukanye hamwe nibikoresho bitandukanye mugihe kiri imbere.