Ni iki hypromellose ikora ku mubiri?

Hypromellose, izwi kandi nka hydroxypropyl methylcellulose (HPMC), ni polymer synthique ikomoka kuri selile. Bikunze gukoreshwa mu nganda zitandukanye, zirimo imiti, amavuta yo kwisiga, n'ibiribwa. Mubuvuzi, hypromellose ifite progaramu nyinshi kubera imiterere yihariye.

1. Intangiriro kuri Hypromellose:

Hypromellose ni polymer hydrophilique ikora igisubizo kibonerana, kibonerana iyo gishonge mumazi. Bikunze gukoreshwa nkibintu bidakora muburyo bwa farumasi kugirango bitezimbere ibicuruzwa nkibicucu, ituze, na bioavailability. Hypromellose ikoreshwa cyane muburyo bukomeye bwo mu kanwa, imyiteguro y'amaso, hamwe nibisobanuro byingenzi.

2. Gukoresha imiti:

a. Impapuro zikoreshwa mu kanwa:

Mu miti yo mu kanwa, hypromellose ikora intego zitandukanye:

Binder: Ifasha guhuza ibikoresho bya farumasi ikora (APIs) hamwe kugirango ibe ibinini cyangwa capsules.

Disintegrant: Hypromellose yorohereza gucamo ibinini cyangwa capsules mu nzira ya gastrointestinal, bigatera kurekura ibiyobyabwenge no kubyakira.

Filime Yahoze: Ikoreshwa mugukora firime yoroheje, ikingira ikingira ibinini kugirango igenzurwe-isohoka cyangwa guhisha uburyohe budashimishije.

b. Amaso y'amaso:

Mu bitonyanga by'amaso n'amavuta, hypromellose ikora nka:

Viscosity Modifier: Yongera ubwiza bwibitonyanga byamaso, itanga igihe kinini cyo guhura nubuso bwa ocular no kongera imiti.

Amavuta yo kwisiga: Hypromellose isiga amavuta hejuru yijisho, ikagabanya gukama no kutoroherwa bijyana nibihe nka syndrome yumaso yumye.

c. Ingingo z'ingenzi:

Mubicuruzwa byingenzi nka cream, geles, namavuta, hypromellose ikora nka:

Gelling Agent: Ifasha gukora geli imeze nka gel, itezimbere ikwirakwizwa ryibicuruzwa kuruhu.

Moisturizer: Hypromellose igumana ubushuhe, ikayobora uruhu kandi ikarinda gutakaza amazi.

3. Uburyo bwibikorwa:

Uburyo bwa Hypromellose bwibikorwa biterwa nuburyo bukoreshwa:

Ubuyobozi bwo mu kanwa: Iyo bwinjiye, hypromellose irabyimba iyo ihuye n’amazi mu nzira ya gastrointestinal, bigatera gusenyuka no gusesa ifishi ya dosiye. Ibi bituma habaho kurekurwa no kwinjiza imiti.

Gukoresha Amaso: Mu bitonyanga by'amaso, hypromellose yongerera ubwiza bwigisubizo, ikongerera igihe cyo guhuza amaso no kongera ibiyobyabwenge. Itanga kandi amavuta yo kugabanya gukama no kurakara.

Gushyira mu bikorwa ingingo: Nka agent, hypromellose ikora urwego rukingira uruhu, ikarinda gutakaza ubushuhe kandi ikorohereza kwinjiza ibintu bikora.

4. Umwirondoro wumutekano:

Hypromellose isanzwe ifatwa nkumutekano kugirango ikoreshwe mu miti yimiti, kwisiga, nibiribwa. Ntabwo ari uburozi, ntiburakaza, kandi ntabwo allerge. Nyamara, abantu bafite hyperensitivite izwi kubikomoka kuri selile bagomba kwirinda ibicuruzwa birimo hypromellose. Byongeye kandi, ibitonyanga byamaso birimo hypromellose bishobora gutera guhita byerekanwa nyuma yubuyobozi, mubisanzwe bikemurwa vuba.

5. Ingaruka zishobora Kuruhande:

Mugihe hypromellose yihanganirwa nabantu benshi, ingaruka zimwe zidasanzwe zishobora kubaho, harimo:

Imyitwarire ya allergique: Mubantu bumva neza, ibyiyumvo birenze urugero nko guhinda, gutukura, cyangwa kubyimba bishobora kugaragara iyo uhuye nibicuruzwa birimo hypromellose.

Kurakara kwa Ocular: Ibitonyanga by'amaso birimo hypromellose birashobora gutera uburakari bworoheje, gutwikwa, cyangwa kwinuba.

Ihungabana rya Gastrointestinal: Mubihe bidasanzwe, imiti yo mu kanwa irimo hypromellose irashobora gutera ibimenyetso byigifu nka isesemi, kubyimba, cyangwa impiswi.

Hypromellose ni polymer itandukanye hamwe na farumasi zitandukanye zikoreshwa mu bya farumasi, harimo imiterere ya dosiye ikomeye yo mu kanwa, imyiteguro y'amaso, hamwe na formulaire yibanze. Itezimbere ibicuruzwa nkibicucu, ituze, hamwe na bioavailable, kunoza itangwa ryibiyobyabwenge no kubahiriza abarwayi. Nubwo ikoreshwa cyane kandi muri rusange ni umutekano w’umutekano, abantu bafite hyperensitivite izwi ku nkomoko ya selile bagomba gukoresha ibicuruzwa birimo hypromellose bafite ubwitonzi. Muri rusange, hypromellose igira uruhare runini mubikorwa bya farumasi bigezweho, bigira uruhare mu mikorere n’umutekano by’imiti n’ibicuruzwa byita ku buzima.