Ni ubuhe buryo bwihariye bukoreshwa na selile ya selile mu nganda zimiti?

Gutegura-kurekura no kugenzura-kurekura imyiteguro: Ethers ya selile nka HPMC (hydroxypropyl methylcellulose) ikoreshwa nkibikoresho bya hydrogel skeleton mugutegura-kurekura. Irashobora kugenzura igipimo cyo kurekura ibiyobyabwenge mumubiri wumuntu kugirango bigere ku ngaruka zo kuvura. Urwego rwo hasi rwa viscosity HPMC irashobora gukoreshwa nkibikoresho bifata, byabyimbye kandi bigahagarika, mugihe urwego rwo hejuru rwinshi rwa HPMC rukoreshwa mugutegura ibikoresho bivanze skeleton ikomeza-kurekura ibinini, capsules ihoraho-irekura, hamwe na hydrophilique gel skeleton ikomeza kurekura.

Igikoresho cyo gukora firime: HPMC ifite imiterere myiza yo gukora firime, kandi firime yakozwe irasa, iragaragara, irakomeye, kandi ntabwo byoroshye kuyubahiriza. Irashobora guteza imbere ibiyobyabwenge kandi ikarinda ibara. Ubwinshi bwa HPMC ni 2% kugeza 10%.

Ibikoresho bya farumasi: Ethers ya selile igira uruhare runini mugutegura ibishushanyo mbonera nkibikoresho bya farumasi, nka pellet irekura-isohoka, skeleton ikomeza-kurekura, imyiteguro irekuye-irekura, capsules irekura-irekura, firime yibiyobyabwenge ikomeza, kurekura imyiteguro hamwe namazi arambye-arekura.

Microcrystalline Cellulose (MCC): MCC ni uburyo bwa selile ikoreshwa cyane mu nganda zimiti, cyane cyane mu guhonyora mu buryo butaziguye no guhunika byumye nko guhuza uruziga kugira ngo utegure ibinini cyangwa granules.

Bioadhesives: Ether ya selulose, cyane cyane ibikomoka kuri etheronique na anionic ether nka EC (Ethylcellulose), HEC (hydroxyethylcellulose), HPC (hydroxypropylcellulose), MC (methylcellulose), CMC (carboxymethylcellulose) cyangwa HPMC (hydroxypropylmethylcellulose). Izi polymers zirashobora gukoreshwa mumunwa, ocular, vaginal na transdermal bioadhesives, wenyine cyangwa ufatanije nizindi polymers.

Thickeners and Stabilisers: Ibikomoka kuri selile bikoreshwa cyane mugukomeza ibisubizo byibiyobyabwenge hamwe na sisitemu yo gukwirakwiza nka emulisiyo no guhagarika. Izi polymers zirashobora kongera ubukonje bwibisubizo bidafite imiti nkibisubizo bishingiye ku kama. Kongera ubwiza bwibisubizo byibiyobyabwenge birashobora kunoza bioavailability yimyiteguro yibanze na mucosal.

Uzuza: Cellulose n'ibiyikomokaho bikunze gukoreshwa nk'uzuza muburyo bukomeye bwa dosiye nka tableti na capsules. Bihujwe nibindi bintu byinshi biva mu mahanga, imiti ya farumasi, kandi ntibigogorwa na enzymes ya gastrointestinal.

Binders: Ethers ya selile ikoreshwa nka binders mugihe cya granulation kugirango ifashe granules gukora no gukomeza ubusugire bwayo.

Capsules yibihingwa: Ethers ya selile nayo ikoreshwa mugukora capsules yibihingwa, ibidukikije byangiza ibidukikije ubundi buryo bukomoka ku nyamaswa gakondo.

Sisitemu yo gutanga ibiyobyabwenge: Ethers ya selile irashobora gukoreshwa mugutezimbere uburyo butandukanye bwo gutanga ibiyobyabwenge, harimo kugenzura-kurekura no gutinda kurekurwa, hamwe na sisitemu yo gusohora urubuga cyangwa igihe cyihariye cyo gusohora ibiyobyabwenge.

Ikoreshwa rya selile ya selile mu nganda zimiti ikomeje kwaguka, kandi hamwe niterambere ryimiterere ya dosiye nshya hamwe nibisohoka bishya, biteganijwe ko igipimo cy’isoko ryacyo giteganijwe kwaguka kurushaho.