Nibihe bintu nyamukuru bigize imiti ya HPMC?

Hydroxypropyl Methylcellulose (HPMC) ni uruganda rutandukanye rukoreshwa cyane mu nganda zitandukanye kubera imiterere yihariye y’imiti. Iyi polymer ikomoka kuri selile, polymer karemano iboneka murukuta rw'utugingo ngengabuzima, binyuze mu ruhererekane rwo guhindura imiti. HPMC yerekana ibintu byinshi byimiti yimiti, bigatuma ikoreshwa mubikoresho bya farumasi, ubwubatsi, ibiryo, amavuta yo kwisiga, nibindi byinshi.

Kamere ya Hydrophilique: Imwe mu miterere yingenzi yimiti ya HPMC ni imiterere ya hydrophilique. Kubaho kwa hydroxyl (-OH) mumugongo wa selile ya selile bituma HPMC ibora cyane amazi. Uyu mutungo uyemerera gushonga mumazi kugirango ube ibisubizo bya viscous colloidal solutions, ibona ibisabwa mubikorwa bitandukanye nka farumasi nibiribwa.

Viscosity: HPMC yerekana ubwinshi bwubwiza bitewe nibintu nkuburemere bwa molekile, urugero rwo gusimburwa, hamwe no kwibanda kubisubizo. Irashobora guhuzwa kugirango yuzuze ibisabwa byihariye bya viscosity mubisabwa bitandukanye, harimo nkibibyimbye, stabilisateur, cyangwa umukozi ukora firime.

Imiterere ya firime: HPMC ifite ubushobozi bwo gukora firime zibonerana kandi zoroshye iyo zishonge mumazi. Uyu mutungo ukoreshwa mu nganda zimiti mugutwikira ibinini no mubiribwa byibiribwa bya firime ziribwa kubicuruzwa.

Ubushuhe bwa Thermal Gelation: Ibyiciro bimwe bya HPMC byerekana ibintu bizwi nka "thermal gelation" cyangwa "gel gel point." Iyi mitungo ituma habaho geles ku bushyuhe bwo hejuru, igasubira muri sol iyo imaze gukonja. Ubushyuhe bwa Thermal bukoreshwa mubisabwa nko gusohora ibiyobyabwenge ndetse no kuba umubyimba mwinshi mubiribwa.

pH Ihungabana: HPMC ihagaze neza kumurongo mugari wa pH, kuva acide kugeza kumiterere ya alkaline. Uyu mutungo utuma ukoreshwa muburyo buteganijwe aho pH ihagaze neza, nko muri farumasi, aho ishobora gukoreshwa muguhindura imyirondoro irekura ibiyobyabwenge.

Inertness ya chimique: HPMC ni inert ya chimique, bivuze ko idakora hamwe nimiti myinshi mubihe bisanzwe. Uyu mutungo ugira uruhare mu gutuza no guhuza hamwe ningeri zitandukanye zindi mubigize.

Guhuza nizindi Polymers: HPMC yerekana guhuza neza nizindi polymers ninyongeramusaruro zikoreshwa mubisanzwe. Uku guhuza kwemerera kurema ibivanze hamwe nibintu byongerewe imbaraga kubikorwa byihariye.

Kamere itari iyoni: HPMC ni polymer itari ionic, bivuze ko idatwara umuriro w'amashanyarazi mugisubizo. Iyi mitungo ituma itumva neza itandukaniro ryimbaraga za ionic na pH ugereranije na polymers zishyuzwa, bikazamura ituze ryayo muburyo butandukanye.

Ibinyabuzima bishobora kwangirika: Nubwo bikomoka kuri selile, umutungo ushobora kuvugururwa, HPMC ubwayo ntabwo byoroshye kubora. Nyamara, ifatwa nkibinyabuzima kandi bitangiza ibidukikije ugereranije na polimeri zimwe na zimwe. Imbaraga zirakomeje mugutezimbere ibinyabuzima biva muri selile ya selile nka HPMC kugirango ikorwe neza.

Gukemura muri Organic Solvents: Mugihe gishonga cyane mumazi, HPMC yerekana imbaraga nke mumashanyarazi. Uyu mutungo urashobora kuba ingirakamaro mubisabwa bimwe na bimwe, nko mugutegura imiti irekura-irekurwa aho imiti ikoreshwa mu kugenzura igipimo cy’ibiyobyabwenge.

Hydroxypropyl Methylcellulose (HPMC) ifite imiterere itandukanye yimiti ituma iba ibikoresho byagaciro mubikorwa bitandukanye. Kamere ya hydrophilique, kugenzura ubukonje, ubushobozi bwo gukora firime, gelasi yumuriro, pH ihagaze neza, kutagira imiti, guhuza nizindi polymers, imiterere itari iyoni, hamwe nibiranga imbaraga bigira uruhare runini mugukoresha imiti, ubwubatsi, ibiryo, kwisiga, nibindi. imirima.