Urwego rwa farumasihydroxypropyl methylcellulose (HPMC)ni ibikoresho bikoreshwa mu bya farumasi, bikoreshwa cyane mu nganda zimiti kubera biocompatibilité nziza kandi ihamye.
1. Ibikenerwa mugutegura imiti
HPMC ikunze gukoreshwa nkibintu byoroshye mugutegura imiti, cyane cyane mugutegura ibinini, capsules, granules, nibindi. Kubera ko HPMC ifatanye neza, imikoreshereze yabyo irashobora kongera imbaraga nimbaraga zihamye za tableti.
2. Kugenzura umukozi wo kurekura
HPMC ikoreshwa cyane mugutegura kurekurwa. Igipimo cyo kurekura ibiyobyabwenge kirashobora guhinduka muguhindura uburemere bwa molekuline hamwe nubwiza bwa HPMC. Amazi ashonga ya HPMC atuma akora geles mumazi, bityo igenzura igipimo cyo kurekura ibiyobyabwenge no kugera kumiti irambye. Uyu mutungo ni ingenzi cyane mu kuvura ibiyobyabwenge indwara zidakira nka diyabete na hypertension.
3. Inkoko zo gukemura no guhagarikwa
HPMC, nkikibyimbye, irashobora kongera neza ubwiza bwibisubizo nibihagarikwa kandi bigateza imbere imikorere yimiti. Mu myiteguro y’amazi, ikoreshwa rya HPMC rirashobora kunoza ihagarikwa ryibiyobyabwenge, kwirinda imvura, no kwemeza ibiyobyabwenge.
4. Imyiteguro yo hanze
HPMC nayo ikoreshwa cyane mubitegura hanze (nka cream, geles, ibishishwa, nibindi). Bitewe nuburyo bwiza bwo gufatira hamwe nubushuhe, HPMC irashobora kongera ikwirakwizwa ryuruhu rwuruhu rwimyiteguro yo hanze kandi igateza imbere imiti yibiyobyabwenge. Byongeye kandi, HPMC irashobora gutanga neza mugihe itegura ibinyabuzima kugirango ibashe gukomera neza kuruhu.
5. Imyiteguro y'amaso
Mu myiteguro y'amaso, HPMC ikoreshwa nkigice cyamarira yubukorikori nigitonyanga cyamaso. Ubwiza bwayo bwinshi hamwe nubushuhe burashobora kugabanya neza amaso yumye, gutanga amavuta arambye, no kunoza ihumure ryumurwayi.
6. Abatwara ibiyobyabwenge bya Nano
Mu myaka yashize, HPMC nayo yizwe nk'umuntu utwara ibiyobyabwenge nano. Muguhuza na nanoparticles, HPMC irashobora kunoza bioavailable yibiyobyabwenge, kugabanya uburozi, no kugera kubiyobyabwenge. Ubu bushakashatsi butanga ibitekerezo bishya byo kuvura indwara zidakira nka kanseri.
7. Ibikoresho bya Biomedical
Ibinyabuzima bihuzaHPMCnayo ituma igira akamaro mubikoresho byibinyabuzima. Irashobora gukoreshwa mugutegura ibinyabuzima, scafolds, nibindi, bigatera imbere gukura kwingirabuzimafatizo no kuvuka bundi bushya, kandi bikoreshwa mubuhanga bwububiko nubuvuzi bushya.
8. Ibindi bikorwa
Usibye imikoreshereze yavuzwe haruguru, HPMC ikoreshwa no mubiribwa, kwisiga no mubindi bice nkibibyimbye na stabilisateur. Kurugero, mubiryo, HPMC irashobora gukoreshwa mugutezimbere uburyohe nuburyohe bwibiryo; mu kwisiga, irashobora gukoreshwa nkibyimbye na emulisiferi kugirango itezimbere kandi wumve ibicuruzwa.
Urwego rwa farumasi HPMC rwabaye ibikoresho byingirakamaro mu buhanga mu bya farumasi n’ibinyabuzima bitewe nuburyo bwinshi kandi biocompatibilité nziza. Hamwe niterambere ryubumenyi n’ikoranabuhanga, urugero n’ikoranabuhanga rya HPMC bizakomeza kwaguka, bitange inkunga yo guteza imbere imiti mishya y’imiti n’uburyo bwo kuvura. Mu bihe biri imbere, ubushakashatsi kuri HPMC buzarushaho kuba bwimbitse, bushyireho urufatiro rwo gushyira mu bikorwa mu buryo bwagutse.
Igihe cyo kohereza: Ugushyingo-07-2024