Hypromellose Ibidasanzwe | Gukoresha, Abatanga, nibisobanuro
Hypromellose, izwi kandi nka hydroxypropyl methylcellulose (HPMC), ni ibintu byinshi bikoreshwa mu miti, imiti yo kwisiga, ibikomoka ku biribwa, hamwe n’inganda zitandukanye zikoreshwa mu nganda. Dore incamake ya hypromellose idasanzwe, harimo imikoreshereze yayo, abayitanga, nibisobanuro:
Ikoreshwa:
- Imiti ya farumasi: Hypromellose ikoreshwa cyane nkibikoresho bya farumasi muburyo bwa dosiye ikomeye nka tableti, capsules, na granules. Ikora nka binder, idatandukana, ikabyimbye, kandi ikora firime, igira uruhare mumiterere yumubiri nubukanishi bwimiterere ya dosiye.
- Ophthalmic Solutions: Mu mikorere y'amaso, hypromellose ikoreshwa nk'amavuta yo kwisiga no kongera ububobere mu bitonyanga by'amaso n'amavuta kugira ngo atume amazi ya ocular atwara kandi yongere igihe cyo gutura ibiyobyabwenge ku buso bwa ocular.
- Imyiteguro yibanze: Hypromellose yinjijwe mubintu byingenzi nka cream, geles, hamwe na lisansi nkibikoresho byongera umubyimba, emulisiferi, na stabilisateur kugirango byongere ibicuruzwa, bikwirakwizwa, hamwe nubuzima bwubuzima.
- Kugenzura-Kurekura: Hypromellose ikoreshwa muburyo bugenzurwa-kurekurwa no gukomeza-kurekura kugirango ihindure ibikorwa byo kurekura ibiyobyabwenge, itanga imyirondoro yagutse yo kurekura ibiyobyabwenge no kurushaho kubahiriza abarwayi.
- Ibicuruzwa byibiribwa: Mu nganda zibiribwa, hypromellose ikoreshwa nkibintu byongera umubyimba, stabilisateur, na emulisiferi mubicuruzwa bitandukanye byibiribwa, birimo isosi, imyambarire, desert, nibicuruzwa bitetse.
- Amavuta yo kwisiga: Hypromellose yinjizwa muburyo bwo kwisiga nka cream, amavuta yo kwisiga, hamwe nibicuruzwa byo kwisiga nkibikoresho byongera umubyimba, firime yahoze, hamwe nububiko bugumana ubushuhe kugirango byongere ibicuruzwa nibikorwa.
Abatanga isoko:
Hypromellose idasanzwe iraboneka kubatanga isoko kwisi yose. Bamwe mubatanga isoko ninganda zirimo:
- Ashland Global Holdings Inc.: Ashland itanga ibicuruzwa byinshi bya hypromellose munsi yizina rya Benecel® na Aqualon ™, bigaburira imiti nubuvuzi bwihariye.
- Kima Chemical Co., Ltd: Kima Chemical itanga ibicuruzwa bishingiye kuri hypromellose munsi yizinaKIMACELL, zikoreshwa muri farumasi, ibiryo, hamwe ninganda zikoreshwa.
- Shin-Etsu Chemical Co., Ltd.: Shin-Etsu ikora ibicuruzwa bishingiye kuri hypromellose ku izina rya Pharmacoat ™, ikora imiti, ibiryo, n’amavuta yo kwisiga.
- Ibara rya Colorcon: Ibicuruzwa bitanga imiti ya hypromellose ishingiye kumiti yiswe Opadry®, yagenewe gushushanya ibinini bya firime no gutezimbere.
- JRS Pharma: JRS Pharma itanga ibicuruzwa bitandukanye bya hypromellose ku izina rya Vivapur®, bigenewe cyane cyane imiti ikoreshwa nka farumasi nko guhuza ibinini, gusenyuka, no kurekurwa.
Ibisobanuro:
Ibisobanuro kuri hypromellose bidasanzwe birashobora gutandukana bitewe nibigenewe gukoreshwa nibisabwa n'amategeko. Ibisobanuro rusange birimo:
- Viscosity: Hypromellose iraboneka mubyiciro bitandukanye byijimye, mubisanzwe kuva hasi kugeza hejuru cyane, kugirango uhuze ibyifuzo byihariye.
- Ingano ya Particle: Ingano yikwirakwizwa rishobora kugira ingaruka kumiterere no kugabanuka kwifu ya hypromellose, bigira ingaruka kubikorwa byo gukora tablet.
- Ibirimo Ubushuhe: Ibirimwo nibintu byingenzi bishobora kugira ingaruka kumikorere no mumikorere ya hypromellose.
- Isuku n’umwanda: Ibisobanuro byera, kimwe nimbibi zanduye nkibyuma biremereye, ibishishwa bisigara, hamwe na mikorobe zanduza, byemeza ubuziranenge numutekano wibicuruzwa bya hypromellose kubikoresha imiti nibiribwa.
- Ubwuzuzanye: Hypromellose igomba guhuzwa nibindi bicuruzwa hamwe nibikoresho bikora muburyo bwo gukora, kimwe nuburyo bwo gutunganya nibikoresho bikoreshwa mubikorwa.
Mugihe gikomoka kuri hypromellose idasanzwe, ni ngombwa kubona ibyemezo byisesengura (CoA) hamwe nibyangombwa byubahirizwa nababitanga kugirango hamenyekane ko ibicuruzwa byujuje ibyangombwa bisabwa hamwe nubuziranenge bugenewe gusaba. Byongeye kandi, ubufatanye nabatanga isoko babishoboye no kubahiriza imikorere myiza yinganda (GMP) ningirakamaro kugirango harebwe ubuziranenge, guhoraho, no kubahiriza amabwiriza ya hypromellose.
Igihe cyo kohereza: Gashyantare-09-2024