HPMC kubuvuzi

HPMCkubuvuziyabaye imwe mu mubare munini waubuvuzi kandiimiti ya farumasi mu gihugu no hanze yacyo, kubera ko HPMC yubuvuzi ifite ibyiza abandi baguzi badafite.

1. Amazi meza

HPMC yo kuvura irashonga mumazi akonje munsi ya 40 ℃ cyangwa 70% Ethanol. Ntishobora gushonga mumazi ashyushye hejuru ya 60 but, ariko irashobora gufungurwa.

2. Inertia yimiti

HPMC y'ubuvuzi ni iy'uturemangingo tutari ionic selile, igisubizo cyacyo ntigifite ionic charge hamwe n'umunyu w'icyuma cyangwa ibinyabuzima bivangwa na ionic, bityo rero mugutegura umusaruro, ibindi bicuruzwa ntibabyitwaramo.

3. Guhagarara

Irahagaze kuri acide na base, kandi irashobora kubikwa murwego rwa PH 3 ~ 11 igihe kirekire nta mpinduka zigaragara mubyiza. HPMC igisubizo cyamazi gifite imbaraga zo kurwanya kandi gishobora kugumya guhagarara neza mububiko bwigihe kirekire. Ibikoresho bya farumasi bifashisha HPMC mubuvuzi, ubuziranenge bwabyo kuruta gukoresha ibicuruzwa gakondo (nka dextrin, krahisi, nibindi) nibyiza.

4. Guhindura ibishishwa

Ibikomoka kuri HPMC biva mubwiza butandukanye birashobora guhuzwa ukurikije ibipimo bitandukanye, ububobere bwacyo burashobora guhinduka ukurikije amategeko amwe, kandi bukagira umubano mwiza, bityo birashobora gutorwa ukurikije ibikenewe. 2. Inertia 5 metabolike inertia HPMC ntabwo yinjiye mumubiri ntabwo ihinduranya, ntabwo itanga ubushyuhe, kubwibyo rero ni imiti itangiza imiti. .

5. Umutekano

HPMCkubuvuzimuri rusange bifatwa nkibidafite uburozi kandi bidatera uburakari.

Hydroxypropyl methyl selulose (HPMC) ni anselileether yakozwe na reaction ya chloromethane na okiside ya propylene hamwe na selile yibanze. Fibre yera cyangwa hafi yera cyangwa ifu ya granular, impumuro nziza. Yakoreshejwe mu nganda zimiti mumyaka irenga 40, kandi yemejwe muri USP19 hamwe nu Bushinwa Pharmacopoeia 1990. Yageze ku bisubizo byiza mubikoresho byo gutwika firime hamwe nibisabwa.

Urwego rwa farumasiHPMChydroxypropyl methyl selulose ifite ibisabwa byinshi kubikoresho fatizo, tekinoroji yumusaruro nubwiza bwibicuruzwa. Mu myaka yashize, bitewe na politiki yo kurengera ibidukikije igenda irushaho gukomera, ibigo bimwe na bimwe bito by’imiti ifasha imiti mu Bushinwa bw’Uburasirazuba ndetse byavuye ku isoko, ndetse n’urwego rwa farumasiHPMChydroxypropyl methyl selulosekubuvuziinganda nazo zagize ingaruka, ubushobozi buke bwo gukora umusaruro muto bwaravuyeho, kandi kwibanda ku bushobozi.