Kubika amazi: HPMC, nkigumana amazi, irashobora gukumira guhumeka cyane no gutakaza amazi mugihe cyo gukira. Uyu mutungo wo gufata amazi utanga amazi ahagije ya sima kandi ukongerera imbaraga nigihe kirekire cya minisiteri. Mugihe cy'ubushyuhe bwo hejuru, gufata amazi ya HPMC ni ngombwa cyane cyane kugirango birinde ko minisiteri itakaza amazi vuba, bityo bigatuma imikorere ya minisiteri ikora.
Imikorere: HPMC igira ingaruka zikomeye kumikorere ya minisiteri. Mugukwirakwiza amavuta, birashobora kugabanya ubushyamirane hagati yuduce, byoroshye kubishyira mubikorwa. Iterambere ryimikorere ritanga inzira nziza yo kubaka.
Mugabanye kugabanuka no gucikamo: Kugabanuka no gutobora nibibazo bisanzwe mubikorwa bya minisiteri, bigatuma kuramba bigira ingaruka. HPMC ikora matrix yoroheje muri minisiteri, igabanya imihangayiko yimbere kandi igabanya ibibaho byo kugabanuka, bityo bikazamura uburebure bwa minisiteri.
Kunoza imbaraga zihindagurika: HPMC yongerera imbaraga imbaraga za minisiteri mukomeza matrix no kunoza isano iri hagati yuduce. Ibi bizamura ubushobozi bwo kurwanya igitutu cyo hanze no kwemeza imiterere yinyubako.
Imiterere yubushyuhe: Kwiyongera kwa HPMC birashobora kubyara ibintu byoroshye hamwe no kugabanya ibiro 11,76%. Iyi poritike nini ifasha mukubika ubushyuhe bwumuriro kandi irashobora kugabanya ubwikorezi bwibintu kugera kuri 30% mugihe hagumye ubushyuhe butajegajega bwa 49W mugihe uhuye nubushyuhe bumwe. Ubushyuhe bwo guhererekanya ubushyuhe binyuze mu kibaho buratandukana nubunini bwa HPMC bwongeweho, kandi umubare munini w’inyongeramusaruro bituma kwiyongera kwa 32,6% mu kurwanya ubushyuhe ugereranije n’uruvange ruvanze.
Kwinjira mu kirere: HPMC irashobora kugabanya ingufu zubutaka bwumuti wamazi bitewe nuko habaho amatsinda ya alkyl, kongera gaze mukwirakwiza, kandi ubukana bwa firime bubble burenze ubw'amazi meza, bigatuma bigorana gusohoka . Uku guhumeka ikirere birashobora kugabanya imbaraga zoguhindura no gukomeretsa za sima ya sima, ariko kandi bizongera kugumana amazi ya minisiteri.
Ingaruka yubushyuhe kuri gelation: Ubushakashatsi bwerekanye ko igipimo cyo kubyimba kiringaniye cya hydrogel ya HPMC kigabanuka hamwe nubushyuhe bwiyongera. Ubushyuhe bugira ingaruka zikomeye kumyitwarire ya hydrogel ya HPMC, ishobora kugira ingaruka kumiterere yubushyuhe butandukanye.
Ingaruka yubushyuhe hamwe na polymer yibanda kubushobozi bwo guhanagura: Imihindagurikire yubushyuhe hamwe nubushakashatsi bwa HPMC bigira ingaruka kumyuka yubushyuhe hamwe nubushobozi bwo guhanagura igisubizo cyamazi. Nkuko kwibumbira hamwe kwa HPMC kwiyongera, imbaraga zingirakamaro zingirakamaro zumuti nazo ziriyongera, bityo bikagabanya imyitwarire yo gukwirakwiza hejuru ya tablet ya Avicel.
HPMC igira ingaruka zikomeye ku mikorere ya minisiteri ku bushyuhe butandukanye, kandi irashobora kunoza uburyo bwo gufata amazi ya minisiteri, kunoza imikorere, kunoza imivurungano, kongera imbaraga mu guhuza imbaraga, kunoza igihe kirekire, kugabanya kugabanuka no gucika, kunoza amazi no kutinjira, kunoza ubukonje. -kurwanya, kandi utezimbere imbaraga zingirakamaro. Ibiranga bituma HPMC yongerwaho byingenzi kugirango irusheho kuramba.
Igihe cyo kohereza: Ukwakira-29-2024