Kodi kukhuthala kwa HPMC ndi chiyani?

HPMC, kapena Hydroxypropyl Methylcellulose, ndi polima kupanga kwambiri ntchito mankhwala, chakudya, zodzoladzola ndi kumanga minda. Ili ndi zinthu zambiri zabwino kwambiri monga kusungunuka, kukhazikika, kuwonekera komanso kupanga mafilimu monga thickener, zomatira, filimu kale, suspending wothandizira ndi colloid zoteteza.

Ponena za viscosity ya HPMC, ndi lingaliro lovuta kwambiri chifukwa kukhuthala kumakhudzidwa ndi zinthu zambiri, monga ndende, kulemera kwa maselo, zosungunulira, kutentha ndi kumeta ubweya.

Ubale pakati pa kulemera kwa maselo ndi kukhuthala: Kulemera kwa maselo a HPMC ndi chimodzi mwazinthu zofunika zomwe zimatsimikizira kukhuthala kwake. Nthawi zambiri, kulemera kwa maselo kumapangitsa kuti HPMC ikhale yamphamvu kwambiri. Choncho, opanga nthawi zambiri amapereka mankhwala a HPMC ndi zolemera zosiyana za maselo kuti akwaniritse zosowa za mafakitale osiyanasiyana. Kulemera kwa molekyulu nthawi zambiri kumawonetsedwa ngati K mtengo (monga K100, K200, etc.). Kukula kwa mtengo wa K, kumapangitsanso kukhuthala.

Zotsatira za ndende: Kukhuthala kwa HPMC m'madzi kumawonjezeka ndikuwonjezeka kwa ndende. Mwachitsanzo, 1% ndende ya HPMC yankho likhoza kukhala ndi mamasukidwe akayendedwe kangapo kuposa yankho la 0.5%. Izi zimalola mamasukidwe akayendedwe a yankho kuti aziwongoleredwa ndikusintha kuchuluka kwa HPMC mukugwiritsa ntchito.

Mmene zosungunulira: HPMC akhoza kusungunuka m'madzi kapena zosungunulira organic, koma zosungunulira zosiyanasiyana zimakhudza mamasukidwe ake akayendedwe. Nthawi zambiri, HPMC imakhala ndi kusungunuka kwabwino m'madzi ndipo kukhuthala kwake kumakhala kwakukulu, pomwe kukhuthala kwa zosungunulira za organic kumasiyanasiyana malinga ndi polarity ya zosungunulira komanso kuchuluka kwa m'malo mwa HPMC.

Zotsatira za kutentha: Kukhuthala kwa njira ya HPMC kumasintha ndi kutentha. Nthawi zambiri, mamasukidwe akayendedwe a HPMC njira amachepetsa pamene kutentha ukuwonjezeka. Ichi ndi chifukwa kuwonjezeka kutentha kumabweretsa mofulumira maselo kuyenda ndi kuchuluka fluidity ya yankho, amene amachepetsa mamasukidwe akayendedwe.

Zotsatira za kumeta ubweya wa ubweya: Njira ya HPMC ndi madzi osakhala a Newtonian, ndipo kukhuthala kwake kumasintha ndi kumeta ubweya. Izi zikutanthauza kuti panthawi yogwedeza kapena kupopera, kukhuthala kumasintha ndi mphamvu ya opaleshoniyo. Nthawi zambiri, yankho la HPMC limawonetsa mikhalidwe yometa ubweya wa ubweya, ndiye kuti, kukhuthala kumachepa pamitengo yometa ubweya wambiri.

Magiredi ndi mafotokozedwe a HPMC: Magiredi osiyanasiyana azinthu za HPMC alinso ndi kusiyana kwakukulu pakukhuthala. Mwachitsanzo, otsika mamasukidwe akayendedwe kalasi HPMC mankhwala angakhale ndi mamasukidwe akayendedwe a 20-100 mPas pa 2% ndende, pamene mkulu mamasukidwe akayendedwe kalasi HPMC mankhwala angakhale ndi mamasukidwe akayendedwe ku 10,000-200,000 mPas pa ndende yomweyo. Chifukwa chake, posankha HPMC, ndikofunikira kusankha kalasi yoyenera ya viscosity kutengera zomwe mukufuna.

Njira zoyeserera: Kukhuthala kwa HPMC nthawi zambiri kumayesedwa ndi viscometer kapena rheometer. Njira zoyeserera zodziwika bwino zimaphatikizapo viscometer yozungulira ndi capillary viscometer. Miyezo yoyesera monga kutentha, kuyika, mtundu wa zosungunulira, ndi zina zotero zimatha kukhudza kwambiri zotsatira, kotero kuti magawowa amayenera kuyang'aniridwa mosamalitsa poyesedwa.

Kukhuthala kwa HPMC ndi gawo lovuta lomwe limakhudzidwa ndi zinthu zingapo, ndipo kusinthika kwake kumapangitsa kuti igwiritsidwe ntchito mosiyanasiyana. Kaya muzakudya, mankhwala, zomangira kapena zodzoladzola mafakitale, kumvetsa ndi kulamulira mamasukidwe akayendedwe a HPMC ndi chimodzi mwa zinthu zofunika kuonetsetsa khalidwe la mankhwala ndi ntchito.