Methyl cellulose (MC) ndi hydroxypropyl methyl cellulose (HPMC) ndi zotuluka ziwiri za cellulose zomwe zimagwiritsidwa ntchito kwambiri m'makampani, zomangamanga, zamankhwala, chakudya ndi magawo ena. Ngakhale ali ofanana m'mapangidwe, ali ndi katundu wosiyana ndipo Pali kusiyana kwakukulu pakugwiritsa ntchito ndi njira zopangira.
1. Kusiyana kwa kapangidwe ka mankhwala
Methylcellulose (MC) ndi hydroxypropylmethylcellulose (HPMC) onse amachokera ku mapadi achilengedwe ndipo amasinthidwa ndi mankhwala a cellulose ether. Koma kusiyana kwawo makamaka kwagona pa mtundu ndi kuchuluka kwa magulu olowa m'malo.
Methyl cellulose (MC)
MC imapangidwa posintha magulu a hydroxyl pa cellulose ndi magulu a methyl (ie -OCH₃). Kapangidwe ka mankhwala a MC makamaka amakhala ndi magulu olowa m'malo a methyl pa tcheni chachikulu cha cellulose, ndipo kulowetsedwa kwake kumakhudza kusungunuka kwake ndi katundu wake. MC nthawi zambiri imasungunuka m'madzi ozizira koma osati m'madzi otentha.
Hydroxypropyl methylcellulose (HPMC)
HPMC imasinthidwanso pamaziko a methylcellulose, posintha gawo lamagulu a hydroxyl ndi methyl (-CH₃) ndi hydroxypropyl (-CH₂CH(OH)CH₃). Poyerekeza ndi MC, kapangidwe ka maselo a HPMC ndizovuta kwambiri, hydrophilicity yake ndi hydrophobicity ndizoyenera, ndipo zimatha kusungunuka m'madzi ozizira komanso otentha.
2. Kusiyana thupi ndi mankhwala katundu solubility
MC: Methylcellulose nthawi zambiri imakhala yabwino kusungunuka m'madzi ozizira, koma imapanga gel pamene kutentha kwakwera. M'madzi otentha, MC imakhala yosasungunuka, kupanga gel osakaniza.
HPMC: Hydroxypropyl methylcellulose ikhoza kusungunuka mofanana m'madzi ozizira ndi otentha, imakhala ndi kutentha kwakukulu kwa kutentha, ndipo kusungunuka kwake kumakhala kokhazikika kuposa MC.
Kutentha kotentha
MC: MC ili ndi mphamvu zotentha zotentha. Kutentha kukakwera kufika pamlingo wina, kumapanga gel osakaniza ndikutaya kusungunuka kwake. Khalidweli limapangitsa kuti likhale ndi ntchito zapadera m'mafakitale omanga ndi opanga mankhwala.
HPMC: HPMC ilinso ndi zinthu zina zotentha, koma mawonekedwe ake a gel kutentha ndi apamwamba ndipo liwiro la mapangidwe a gel ndi locheperako. Poyerekeza ndi MC, ma gel otenthetsera a HPMC amatha kuwongoleredwa motero amakhala opindulitsa pamapulogalamu omwe amafunikira kutentha kwambiri.
Zochita pamwamba
MC: MC ili ndi zochitika zochepa. Ngakhale itha kugwiritsidwa ntchito ngati emulsifier kapena thickener muzinthu zina, zotsatira zake sizofunikira ngati HPMC.
HPMC: HPMC ili ndi ntchito zamphamvu zapamtunda, makamaka kuyambitsa gulu la hydroxypropyl, zomwe zimapangitsa kuti zikhale zosavuta kutulutsa, kuyimitsa ndi kukhuthala mu njira. Choncho, amagwiritsidwa ntchito kwambiri monga chowonjezera mu zokutira ndi zomangira.
Kulekerera kwa mchere ndi pH kukhazikika
MC: Methylcellulose samalekerera bwino mchere ndipo amakonda mvula m'malo okhala mchere wambiri. Ili ndi kusakhazikika bwino m'malo a asidi ndi alkali ndipo imakhudzidwa mosavuta ndi mtengo wa pH.
HPMC: Chifukwa cha kukhalapo kwa hydroxypropyl substituent, kulolerana kwa mchere wa HPMC ndikwabwinoko kuposa MC, ndipo kumatha kusungunuka bwino komanso kukhazikika mumitundu yambiri ya pH, motero ndikoyenera kumadera osiyanasiyana amankhwala.
3. Kusiyana kwa njira zopangira
Kupanga kwa MC
Methylcellulose amapangidwa kudzera mu methylation reaction ya cellulose, nthawi zambiri amagwiritsa ntchito methyl chloride kuchitapo kanthu ndi cellulose yamchere m'malo mwa magulu a hydroxyl mu ma cellulose. Izi zimafuna kuwongolera momwe zinthu zilili kuti zitsimikizire kuchuluka koyenera m'malo, komwe kumakhudza kusungunuka ndi zina physicochemical katundu womaliza.
Kupanga kwa HPMC
Kupanga kwa HPMC kumatengera methylation ndipo kumawonjezera hydroxypropylation reaction. Ndiye kuti, pambuyo pa methylation reaction ya methyl chloride, propylene oxide imakumana ndi mapadi kuti apange cholowa cha hydroxypropyl. Kuyambitsidwa kwa gulu la hydroxypropyl kumapangitsa kuti HPMC isungunuke komanso kuti ikhale ndi mphamvu ya hydration, zomwe zimapangitsanso kupanga kwake kukhala kovuta komanso mtengo wokwera pang'ono kuposa MC.
4. Kusiyana m'magawo ofunsira
Zomangamanga munda
MC: MC nthawi zambiri imagwiritsidwa ntchito pomanga, makamaka ngati thickener, chosungira madzi ndi zomatira mumatope owuma ndi putty powder. Komabe, chifukwa cha kutentha kwake kwa gelling, MC ikhoza kulephera m'malo otentha kwambiri.
HPMC: HPMC imagwiritsidwa ntchito kwambiri pomanga. Chifukwa imakhalanso ndi kukhazikika kwabwino m'malo otentha kwambiri, ndiyoyenera kwambiri pazochitika zomwe zimafuna kulekerera kutentha kwakukulu, monga zomatira matailosi, matope otsekemera ndi malo odzipangira okha. .
Minda ya mankhwala ndi zakudya
MC: Methylcellulose amagwiritsidwa ntchito ngati disintegrant ndi thickener pamapiritsi pokonzekera mankhwala. Amagwiritsidwanso ntchito muzakudya zina ngati chowonjezera komanso chowonjezera cha fiber.
HPMC: HPMC ili ndi zabwino zambiri pazamankhwala. Chifukwa cha kusungunuka kwake kosasunthika komanso kuyanjana kwabwino kwachilengedwe, nthawi zambiri amagwiritsidwa ntchito popanga mafilimu osasunthika komanso zipolopolo za makapisozi amankhwala. Kuphatikiza apo, HPMC imagwiritsidwanso ntchito kwambiri m'makampani azakudya, makamaka popanga makapisozi amasamba.
Gawo la zokutira ndi utoto
MC: MC ili ndi zokhuthala bwino komanso zopanga filimu, koma kukhazikika kwake ndi kusinthasintha kwamphamvu pakutha pa yankho sizabwino ngati HPMC.
HPMC: HPMC imagwiritsidwa ntchito kwambiri mumakampani opanga utoto ndi utoto chifukwa cha kukhuthala kwake, emulsification ndi kupanga filimu, makamaka ngati chowonjezera komanso chowongolera muzopaka zamadzi, zomwe zitha kusintha kwambiri ntchito yomanga ndi pamwamba pa zokutira. . Zotsatira.
5. Kuteteza chilengedwe ndi chitetezo
Onse a MC ndi HPMC amasinthidwa kuchokera ku cellulose yachilengedwe ndipo amakhala ndi kuwonongeka kwachilengedwe komanso kuteteza chilengedwe. Zonsezi ndizopanda poizoni komanso zosavulaza zomwe zimagwiritsidwa ntchito ndipo zimatsatira zofunikira zachitetezo cha chilengedwe, choncho ndizotetezeka kwambiri kuti zigwiritsidwe ntchito pazakudya, mankhwala ndi zodzoladzola.
Ngakhale methylcellulose (MC) ndi hydroxypropylmethylcellulose (HPMC) ndi ofanana mu kapangidwe ka mankhwala, chifukwa cha magulu osiyanasiyana olowa m'malo, kusungunuka kwawo, kutsekemera kwamafuta, ntchito zapamtunda, kupanga ndi kugwiritsa ntchito ndizosiyana. Pali kusiyana koonekeratu m'minda ndi mbali zina. MC ndiyoyenera kumadera otentha otsika komanso kukhuthala kosavuta komanso zofunikira zosungira madzi, pomwe HPMC ndiyoyeneranso ntchito zovuta zamakampani, zamankhwala ndi zomangamanga chifukwa cha kusungunuka kwake kwabwino komanso kukhazikika kwamafuta.
Nthawi yotumiza: Oct-25-2024