Hydroxypropylmethylcellulose (HPMC) ndi polymer yogwira ntchito zambiri yochokera ku cellulose yachilengedwe. Amagwiritsidwa ntchito m'mafakitale osiyanasiyana, kuphatikizapo mankhwala, zakudya, zomangamanga ndi zodzoladzola. Kupanga kwa HPMC kumaphatikizapo zinthu zosiyanasiyana zopangira komanso njira zambiri.
Ma cellulose:
Gwero: Zopangira zazikulu za HPMC ndi cellulose, ma carbohydrate ovuta omwe amapezeka m'makoma a cell ya zomera. Magwero ambiri a cellulose popanga HPMC ndi zamkati zamatabwa, koma magwero ena monga ma linter a thonje angagwiritsidwenso ntchito.
Kukonzekera: Ma cellulose nthawi zambiri amathandizidwa kuti achotse zonyansa ndikusinthidwa kukhala mawonekedwe oyenera kuti asinthe.
Pansi:
Mtundu: Sodium hydroxide (NaOH) kapena potaziyamu hydroxide (KOH) imagwiritsidwa ntchito ngati maziko pamagawo oyambilira a HPMC kupanga.
Ntchito: Alkali imagwiritsidwa ntchito pochiza cellulose, kupangitsa kuti ifufuze ndikuwononga kapangidwe kake. Njira imeneyi, yotchedwa alkalization, imakonzekeretsa cellulose kuti igwirenso ntchito.
Alkali etherifying agent:
Hydroxypropylating agent: Propylene oxide nthawi zambiri amagwiritsidwa ntchito poyambitsa magulu a hydroxypropyl mu cellulose backbone. Sitepe iyi imapereka kusungunuka ndi zinthu zina zofunika ku cellulose.
Methylating agents: Methyl chloride kapena dimethyl sulfate nthawi zambiri amagwiritsidwa ntchito poyambitsa magulu a methyl pamapangidwe a cellulose, potero amakulitsa mawonekedwe ake onse.
Methylating agent:
Methanol: Methanol imagwiritsidwa ntchito ngati zosungunulira komanso zosungunulira muzochita za methylation. Zimathandizira kuyambitsa magulu a methyl mu unyolo wa cellulose.
Hydroxypropylating agent:
Propylene oxide: Ndiwofunika kwambiri poyambitsa magulu a hydroxypropyl kukhala cellulose. Zomwe zimachitika pakati pa propylene oxide ndi cellulose zimachitika molamulidwa.
chothandizira:
Acid Catalyst: Acid catalyst, monga sulfuric acid, imagwiritsidwa ntchito kulimbikitsa etherification reaction. Amathandizira kuwongolera momwe zimachitikira komanso katundu wazinthu.
Zosungunulira:
Madzi: Madzi amagwiritsidwa ntchito ngati zosungunulira pamagawo osiyanasiyana popanga. Ndikofunikira pakusungunula ma reactants ndikulimbikitsa zomwe zimachitika pakati pa cellulose ndi etherifying agents.
Neutralizer:
Sodium hydroxide (NaOH) kapena potaziyamu hydroxide (KOH): amagwiritsidwa ntchito kuti achepetse zopangira asidi ndikusintha pH panthawi ya kaphatikizidwe.
woyeretsa:
Zothandizira Zosefera: Zothandizira zosiyanasiyana zosefera zitha kugwiritsidwa ntchito kuchotsa zinyalala ndi zinthu zosafunikira kuchokera pazosakanizidwa.
Zotsukira: Kutsuka ndi madzi kapena zosungunulira zina kumathandiza kuchotsa mankhwala otsala ndi zinyalala pa chinthu chomaliza.
Desiccant:
Kuyanika mpweya kapena uvuni: Pambuyo poyeretsedwa, chinthucho chikhoza kukhala mpweya kapena uvuni wouma kuchotsa zosungunulira zotsalira ndi chinyezi.
Woyang'anira khalidwe:
Ma Analytical Reagents: Ma reagents osiyanasiyana amagwiritsidwa ntchito pazifukwa zowongolera kuti awonetsetse kuti zinthu za HPMC zikukwaniritsa magwiridwe antchito ndi zofunikira.
Kupanga kwa hydroxypropyl methylcellulose kumakhudzanso kusintha kwa cellulose kudzera muzochita zingapo zamankhwala. Zida zopangira zikuphatikizapo mapadi, alkali, etherifying agent, chothandizira, zosungunulira, neutralizing agent, purifying agent ndi desiccant, zomwe zimagwira ntchito yofunika kwambiri popanga kaphatikizidwe. Mikhalidwe yeniyeni ndi ma reagents omwe amagwiritsidwa ntchito amatha kusiyanasiyana kutengera zomwe mukufuna komanso kugwiritsa ntchito komaliza kwa hydroxypropyl methylcellulose.
Nthawi yotumiza: Dec-21-2023