Hydroxypropylmethylcellulose (HPMC) ndi polymer yogwira ntchito zambiri yochokera ku cellulose yomwe imagwiritsidwa ntchito kwambiri m'mafakitale osiyanasiyana chifukwa cha mawonekedwe ake apadera. Pawiriyi amapangidwa kudzera muzosintha zingapo zamakemikolo ku cellulose, polima wachilengedwe wopezeka m'makoma a cellulose.
zopangira:
Gwero: Cellulose ndiye chopangira chachikulu cha HPMC, chomwe ndi chochuluka mwachilengedwe komanso chotengedwa ku zomera. Zamkati zamatabwa ndi zikopa za thonje ndizomwe zimachokera ku cellulose.
Kudzipatula: Ntchito yochotsa imaphatikizapo kugwetsa makoma a cellulose ndikulekanitsa ulusi wa cellulose. Njira zosiyanasiyana zamakina ndi zamakina zitha kugwiritsidwa ntchito pazolinga izi.
Propylene oxide:
Gwero: Propylene oxide ndi organic pawiri yochokera ku petrochemical sources.
Ntchito: Propylene oxide imagwiritsidwa ntchito poyambitsa magulu a hydroxypropyl kukhala mamolekyu a cellulose panthawi ya kaphatikizidwe, kupititsa patsogolo kusungunuka kwamadzi ndikusintha mawonekedwe amtundu wa HPMC.
Methyl kloride:
Gwero: Methyl chloride ndi chlorinated hydrocarbon yomwe imatha kupangidwa kuchokera ku methanol.
Ntchito: Methyl chloride imagwiritsidwa ntchito poyambitsa magulu a methyl kukhala ma cellulose mamolekyu, omwe amathandizira kuti hydrophobicity yonse ya HPMC ikhale.
Sodium hydroxide (NaOH):
Gwero: Sodium hydroxide, yomwe imadziwikanso kuti caustic soda, ndiyo maziko amphamvu ndipo imapezeka pamalonda.
Ntchito: NaOH ntchito catalyze anachita ndi kusintha pH mtengo wa anachita osakaniza pa kaphatikizidwe ndondomeko.
Kaphatikizidwe:
The kaphatikizidwe wa HPMC kumafuna njira zingapo, ndi zimene chiwembu akhoza mwachidule motere:
Alkalizing:
Cellulose amathandizidwa ndi sodium hydroxide kuti apange alkaline cellulose.
Ma cellulose a alkali amathandizidwa ndi propylene oxide kuyambitsa magulu a hydroxypropyl.
Methylation:
Ma cellulose a Hydroxypropylated amachitidwanso ndi methyl chloride kuyambitsa magulu a methyl.
Gawo ili limapatsa polima kukhazikika kowonjezera komanso hydrophobicity.
Neutralization ndi kusefa:
Zimene osakaniza anali neutralized kuchotsa owonjezera m'munsi.
Kusefera kunachitika kuti pakhale cellulose yosinthidwa.
Kuchapa ndi kuyanika:
Mankhwala olekanitsidwa amatsukidwa ndikuwumitsidwa kuti apeze hydroxypropyl methylcellulose mu ufa kapena mawonekedwe a granular.
Khalidwe kusungunuka kwa HPMC:
HPMC imasungunuka m'madzi ndipo kusungunuka kwake kumatha kusinthidwa malinga ndi kuchuluka kwa m'malo mwa magulu a hydroxypropyl ndi methyl.
Luso lopanga filimu:
HPMC imapanga makanema osinthika, owoneka bwino oyenera kugwiritsidwa ntchito m'mafakitale azamankhwala ndi zakudya.
Viscosity:
The mamasukidwe akayendedwe a HPMC njira akhoza lizilamulira ndipo nthawi zambiri ntchito monga thickener ndi gelling wothandizira mu formulations zosiyanasiyana.
Thermal gelation:
Magiredi ena a HPMC amawonetsa mawonekedwe a thermogelling, kupanga gel osakaniza akatenthedwa ndikubwerera ku yankho litakhazikika.
Zochitika Pamwamba:
HPMC itha kugwiritsidwa ntchito ngati surfactant, ndipo ntchito yake padziko lapansi imakhudzidwa ndi kuchuluka kwa m'malo.
Mankhwala ogwiritsidwa ntchito a HPMC:
HPMC chimagwiritsidwa ntchito mu mankhwala formulations monga binders, disintegrants, ndi ankalamulira kumasulidwa wothandizira mu mapiritsi ndi makapisozi.
Makampani omanga:
M'gawo la zomangamanga, HPMC imagwiritsidwa ntchito ngati chowonjezera pazinthu zopangira simenti monga matope ndi zomatira matailosi.
makampani azakudya:
HPMC imagwiritsidwa ntchito m'makampani azakudya monga chowonjezera, emulsifier ndi stabilizer muzinthu zosiyanasiyana, kuphatikiza ma sauces, maswiti ndi ayisikilimu.
Zosamalira munthu:
Muzodzoladzola ndi zinthu zosamalira anthu, HPMC imagwiritsidwa ntchito popanga mafuta opaka, mafuta odzola ndi ma shampoos chifukwa chakukhuthala kwake komanso kukhazikika kwake.
Paints ndi Zopaka:
HPMC imawonjezedwa ku utoto ndi zokutira kuti ziwongolere kukhuthala, kukonza magwiridwe antchito komanso kukulitsa mawonekedwe opangira mafilimu.
Mayankho a Ophthalmic:
HPMC imagwiritsidwa ntchito m'madontho a diso ndi misozi yochita kupanga chifukwa cha biocompatibility yake komanso zinthu zomatira.
Pomaliza:
Hydroxypropylmethylcellulose (HPMC) ndi polima wodabwitsa wopangidwa kuchokera ku cellulose yongowonjezwdwa. Zochita zake zambiri komanso ntchito zambiri zimapangitsa kuti ikhale yofunika kwambiri m'mafakitale osiyanasiyana, kuyambira zamankhwala mpaka zomangamanga ndi chakudya. Posankha mosamala zinthu zopangira ndikuwongolera magawo a kaphatikizidwe, ma HPMC okhala ndi makonda amatha kupangidwa kuti akwaniritse zosowa zamitundu yosiyanasiyana. Pomwe ukadaulo ndi zosowa zikupitilira kusinthika, HPMC ikuyenera kukhalabe gawo lalikulu pazatsopano komanso chitukuko chokhazikika chazinthu m'mafakitale onse.
Nthawi yotumiza: Dec-18-2023