Hydroxypropyl methylcellulose (HPMC) ndi polima wosunthika wogwiritsidwa ntchito m'mafakitale osiyanasiyana kuphatikiza mankhwala, zomangamanga, chakudya, ndi zodzola. Ndichochokera ku cellulose chomwe chimawonetsa zinthu zingapo kutengera mtundu wake. Makalasi osiyanasiyana a HPMC amasiyanitsidwa makamaka ndi kukhuthala kwawo, kuchuluka kwa m'malo, kukula kwa tinthu, komanso cholinga chakugwiritsa ntchito.
1. Kalasi ya Viscosity
Viscosity ndi gawo lofunikira lomwe limatanthawuza kalasi ya HPMC. Zimatanthawuza makulidwe kapena kukana kuyenda kwa yankho la HPMC. HPMC ili ndi makulidwe osiyanasiyana kuchokera kumunsi kupita kumtunda ndipo nthawi zambiri imayesedwa mu centipoise (cP) ikasungunuka m'madzi. Magulu ena odziwika bwino a viscosity ndi awa:
Magiredi otsika amakayendedwe (mwachitsanzo, 3 mpaka 50 cP): Magirediwa amagwiritsidwa ntchito m'mapulogalamu omwe amafunikira njira zochepetsera kukhuthala, monga m'makampani azakudya monga zokhazikika, zonenepa, kapena zopangira ma emulsifiers.
Sing'anga mamasukidwe akayendedwe magiredi (mwachitsanzo, 100 kuti 4000 cP): Wapakatikati mamasukidwe akayendedwe HPMC ntchito ankalamulira kumasulidwa formulations ndi monga zomangira piritsi kupanga.
Magiredi owoneka bwino kwambiri (mwachitsanzo, 10,000 mpaka 100,000 cP): Magiredi owoneka bwino nthawi zambiri amagwiritsidwa ntchito pomanga, makamaka matope opangidwa ndi simenti, zomatira, ndi ma pulasitala, pomwe amathandizira kuti azitha kugwira ntchito, kusunga madzi, ndi kumamatira.
2. Digiri ya Kusintha (DS) ndi Molar Substitution (MS)
Mlingo wolowa m'malo umatanthawuza kuchuluka kwa magulu a hydroxyl pa molekyulu ya cellulose omwe amasinthidwa ndi magulu a methoxy (-OCH3) kapena hydroxypropyl (-OCH2CHOHCH3). Mlingo wa m'malo umakhudza kusungunuka, kutentha kwa gelation, ndi kukhuthala kwa HPMC. Makalasi a HPMC amagawidwa kutengera zomwe zili mu methoxy ndi hydroxypropyl:
Zomwe zili mu Methoxy (28-30%): Zomwe zili pamwamba pa methoxy nthawi zambiri zimabweretsa kutsika kwa kutentha kwa gelation ndi ma viscosity apamwamba.
Zomwe zili mu Hydroxypropyl (7-12%): Kuchulukitsa zomwe zili mu hydroxypropyl nthawi zambiri kumapangitsa kusungunuka kwamadzi ozizira ndikuwonjezera kusinthasintha.
3. Kugawa kwa tinthu tating'onoting'ono
Kukula kwa tinthu ting'onoting'ono kwa ufa wa HPMC kumatha kusiyanasiyana, kukhudza kuchuluka kwa kusungunuka kwawo ndi magwiridwe antchito pakugwiritsa ntchito. The finely particles, mofulumira iwo kupasuka, kuwapanga kukhala oyenera ntchito amafuna mofulumira hydration, monga makampani chakudya. Pomanga, ndi bwino kugwiritsa ntchito magiredi okulirapo pakubalalika bwino mu zosakaniza zowuma.
4. Magiredi enieni ogwiritsira ntchito
HPMC imapezeka m'makalasi osiyanasiyana, yogwirizana ndi zosowa zamakampani:
Gulu lamankhwala: Amagwiritsidwa ntchito ngati chophatikizira, choyambirira cha filimu, komanso chowongolera chotulutsa m'njira zapakamwa zolimba. Imakwaniritsa miyezo yoyera ndipo nthawi zambiri imakhala ndi kukhuthala kwake komanso kulowetsa m'malo.
Gulu la zomangamanga: Gulu ili la HPMC limakongoletsedwa kuti ligwiritsidwe ntchito pa simenti ndi zinthu zopangidwa ndi gypsum. Imawongolera kusunga madzi, kugwira ntchito, ndi kumamatira mu pulasitala, matope, ndi zomatira matailosi. Magulu a viscosity apamwamba amagwiritsidwa ntchito m'derali.
Gawo lazakudya: Gawo lazakudya la HPMC limavomerezedwa kuti ligwiritsidwe ntchito ngati chowonjezera chazakudya (E464) ndipo litha kugwiritsidwa ntchito ngati chowonjezera, emulsifier, ndi stabilizer muzinthu zosiyanasiyana, kuphatikiza zowotcha ndi zolowa m'malo mwa mkaka. Iyenera kutsatira malamulo oteteza zakudya ndipo nthawi zambiri imakhala yopanda zodetsedwa.
Gulu la zodzikongoletsera: Pazinthu zosamalira anthu, HPMC imagwiritsidwa ntchito ngati thickener, emulsifier, komanso filimu yakale. Amapereka mawonekedwe osalala amafuta, lotions, ndi ma shampoos.
5. Magiredi osinthidwa
Ntchito zina zimafunikira magiredi osinthidwa a HPMC, pomwe polima amasinthidwa kuti apititse patsogolo zinthu zina:
HPMC yolumikizidwa ndi Mtanda: Kusintha uku kumapangitsa kuti gel azilimba komanso kukhazikika pamapangidwe otulutsidwa.
Hydrophobic modified HPMC: Mtundu uwu wa HPMC umagwiritsidwa ntchito popanga zinthu zomwe zimafuna kuti madzi asamve bwino, monga zokutira ndi utoto.
6. Gel kutentha makalasi
Kutentha kwa gel osakaniza HPMC ndi kutentha komwe yankho limayamba kupanga gel osakaniza. Izo zimatengera mlingo wa m'malo ndi mamasukidwe akayendedwe. Magiredi osiyanasiyana amapezeka kutengera kutentha komwe mukufuna:
Kutsika kwa kutentha kwa gel osakaniza: Magilasi awa amakhala ndi kutentha kocheperako, kuwapangitsa kukhala oyenera nyengo yotentha kapena njira zina zamafakitale zomwe zimafunikira kutentha kochepa.
Kutentha kwakukulu kwa gel osakaniza: Izi zimagwiritsidwa ntchito popanga gel osakaniza pa kutentha kwakukulu, monga mankhwala enaake.
HPMC imapezeka m'makalasi osiyanasiyana kuti ikwaniritse zosowa zamakampani osiyanasiyana. Kusankhidwa kwa kalasi ya HPMC kumadalira kukhuthala komwe mukufuna, kuchuluka kwa m'malo, kukula kwa tinthu, ndi zofunikira zenizeni za ntchito. Kaya amagwiritsidwa ntchito pazamankhwala, zomangamanga, chakudya kapena zodzoladzola, kalasi yoyenera ya HPMC ndiyofunikira kuti mukwaniritse zomwe mukufuna komanso magwiridwe antchito pomaliza.
Nthawi yotumiza: Aug-27-2024