Hypromellose ndi hydrophilic, non-ionic polima kuti ntchito zosiyanasiyana mankhwala ndi mankhwala ntchito, kuphatikizapo mafuta ndi mamasukidwe akayendedwe wothandizila diso madontho, monga ❖ kuyanika mu mapiritsi ndi makapisozi, komanso ngati kupitiriza-kumasulidwa wothandizira mankhwala. machitidwe operekera. Dongosolo la hypromellose limagwirizana ndi mawonekedwe ake apadera a physicochemical, kuphatikiza mphamvu yake yokhala ndi madzi ambiri komanso kuthekera kwake kupanga ma gels pamaso pamadzi.
- Kupaka mafuta: Pankhani ya madontho a diso a hypromellose, njira yoyamba yochitirapo kanthu ndi mafuta. Akagwiritsidwa ntchito pamwamba pa diso, hypromellose imapanga filimu yopyapyala yomwe imathandiza kuchepetsa kukangana pakati pa chikope ndi cornea, motero kuchepetsa kuyanika, kufiira, ndi kuyabwa. Kupaka mafuta kumeneku kumachitika chifukwa cha kuchuluka kwa madzi a hypromellose, omwe amalola kuti azitha kuyamwa ndi kusunga chinyezi kuchokera ku filimu yong'ambika, komanso kufalikira mofanana pamwamba pa diso.
- Viscosity: Hypromellose imathanso kuonjezera kukhuthala kwa mayankho, omwe amatha kuwongolera kusungidwa kwawo pamtunda ndikuwonjezera nthawi yolumikizana ndi diso. Izi ndizofunikira makamaka pankhani ya madontho a diso, chifukwa zingathandize kuonjezera mphamvu zochiritsira za mankhwala.
- Kupaka: Hypromellose imagwiritsidwa ntchito ngati ❖ kuyanika m'mapiritsi ndi makapisozi. Pogwiritsa ntchito izi, zimapanga chitetezo chozungulira mankhwala omwe angathandize kuchepetsa mlingo wa kumasulidwa kwa mankhwala ndi kuteteza mankhwalawa kuti asawonongeke m'mimba kapena m'matumbo. Njira ya hypromellose m'nkhaniyi ikugwirizana ndi kuthekera kwake kupanga chotchinga pakati pa mankhwala ndi malo ozungulira, zomwe zingathandize kupititsa patsogolo kukhazikika ndi bioavailability wa mankhwala.
- Kutulutsidwa Kokhazikika: Hypromellose itha kugwiritsidwanso ntchito ngati wothandizira wokhazikika mumayendedwe operekera mankhwala. Pogwiritsira ntchito mankhwalawa, amagwiritsidwa ntchito popanga matrix ngati gel omwe amatha kuwongolera kutulutsidwa kwa mankhwalawa kwa nthawi yayitali. Dongosolo la hypromellose m'nkhaniyi likugwirizana ndi kuthekera kwake kupanga maukonde a haidrojeni omwe amatha kugwira mamolekyu a mankhwalawa ndikuwongolera kumasulidwa kwawo.
\ njira ya hypromellose imakhudzana ndi mawonekedwe ake apadera a physicochemical, omwe amaphatikiza mphamvu yake yokhala ndi madzi ambiri, kuthekera kwake kupanga ma gels pamaso pamadzi, komanso kuthekera kwake kowonjezera kukhuthala kwa mayankho. Izi zimapangitsa kukhala polima wosunthika komanso wogwiritsidwa ntchito kwambiri m'makampani opanga mankhwala ndi zamankhwala, makamaka popanga madontho a maso, mapiritsi, makapisozi, ndi njira zoperekera mankhwala.
Nthawi yotumiza: Mar-04-2023