Mtengo wa HPMC

Hydroxypropyl Methylcellulose (HPMC) ndi cellulose ether yochokera ku cellulose yachilengedwe, makamaka nkhuni kapena thonje, kudzera munjira zingapo zama mankhwala. Nazi mwachidule zosakaniza ndi katundu wa HPMC:

1. Ma cellulose: Cellulose ndiye chinthu chachikulu mu HPMC. Ndi polysaccharide yochitika mwachilengedwe yopangidwa ndi mayunitsi a glucose obwerezabwereza olumikizidwa pamodzi mu unyolo wautali. Cellulose imagwira ntchito ngati msana wa HPMC ndipo imapereka umphumphu wamapangidwe.
2. Methylation: Msana wa cellulose umasinthidwa ndi mankhwala kudzera mu njira yotchedwa methylation, pomwe methyl chloride imakhudzidwa ndi cellulose pamaso pa alkali kuyambitsa magulu a methyl (-CH3) pa unyolo wa cellulose. Njira ya methylation iyi ndiyofunikira pakukulitsa kusungunuka kwamadzi ndi zinthu zina za cellulose.
3. Hydroxypropylation: Kuphatikiza pa methylation, magulu a hydroxypropyl (-CH2CHOHCH3) amathanso kuyambitsidwa pa unyolo wa cellulose kudzera mu hydroxypropylation. Izi zimasinthanso mawonekedwe a cellulose, kukonza kusungirako madzi, luso lopanga filimu, ndi zina.
4. Etherification: Kukhazikitsidwa kwa magulu a methyl ndi hydroxypropyl pa unyolo wa cellulose amadziwika kuti etherification. Etherification imasintha kapangidwe kake ka cellulose, zomwe zimapangitsa kuti pakhale HPMC yokhala ndi zinthu zapadera zoyenera kugwiritsa ntchito zosiyanasiyana.
5. Katundu Wathupi: HPMC nthawi zambiri imakhala yoyera mpaka yoyera, yopanda fungo, komanso yopanda kukoma. Imasungunuka m'madzi ozizira ndipo imapanga njira zomveka bwino kapena zosokoneza pang'ono kutengera ndende ndi kalasi. HPMC imawonetsa kusungirako bwino kwa madzi, kukhuthala, kupanga mafilimu, ndi ntchito zapamtunda, zomwe zimapangitsa kuti zikhale zofunikira m'mafakitale osiyanasiyana, kuphatikizapo zomangamanga, mankhwala, chakudya, ndi zodzoladzola.

Ponseponse, zopangira zazikulu mu HPMC ndi cellulose, methyl chloride (ya methylation), ndi propylene oxide (ya hydroxypropylation), pamodzi ndi zopangira zamchere ndi zina zomwe zimagwiritsidwa ntchito popanga. Zosakaniza izi zimakumana ndi zochitika zamakina kuti zipange HPMC yokhala ndi zinthu zina zomwe zimapangidwira kuti zikwaniritse zofunikira zamagwiritsidwe osiyanasiyana.