Kodi ma viscosity a HPMC amadzimadzi amasintha bwanji ndi ndende?

Hydroxypropyl Methylcellulose (HPMC) ndi ether yosinthidwa ya cellulose yomwe imagwiritsidwa ntchito kwambiri popanga mankhwala, zowonjezera chakudya, zomangira, zodzoladzola ndi zina. HPMC ali thickening, filimu kupanga, adhesion ndi zina. Ubale pakati pa mamasukidwe akayendedwe ndi ndende ya yankho lake lamadzi ndi lofunika kwambiri pazogwiritsa ntchito zosiyanasiyana.

Makhalidwe amakayendedwe amadzimadzi a HPMC

Makhalidwe oyambira
HPMC amapanga mandala kapena translucent viscous njira pambuyo Kutha m'madzi. Kukhuthala kwake kumakhudzidwa osati ndi kuchuluka kwa HPMC, komanso ndi zinthu monga kulemera kwa maselo, mtundu wolowa m'malo ndi kutentha kwa yankho.

Kulemera kwa mamolekyu: Kulemera kwa maselo a HPMC, kumapangitsanso kukhuthala kwa yankho. Izi ndichifukwa choti ma macromolecules amapanga mawonekedwe ovuta kwambiri omangika mu yankho, zomwe zimawonjezera kukangana pakati pa mamolekyu.
Mtundu wolowa m'malo: Chiŵerengero cha methoxy ndi hydroxypropoxy substituents zimakhudza kusungunuka ndi kukhuthala kwa HPMC. Nthawi zambiri, methoxy ikakhala yapamwamba, kusungunuka kwa HPMC kumakhala bwino komanso kukhuthala kwa yankho kumakhalanso kokwezeka.

Ubale pakati pa ndende ndi mamasukidwe akayendedwe

Dilute solution stage:
Pamene ndende ya HPMC ili yochepa, kuyanjana pakati pa mamolekyu kumakhala kofooka ndipo yankho likuwonetsa katundu wa Newtonian fluid, ndiko kuti, kukhuthala kwake kumakhala kodziimira pawokha.
Panthawi imeneyi, kukhuthala kwa yankho kumawonjezeka mofanana ndi kuwonjezeka kwa ndende. Ubale wa mzerewu ukhoza kuwonetsedwa ndi kuphweka kwa viscosity equation:

Zitha kuwonedwa kuchokera ku data kuti kukhuthala kwa HPMC yamadzimadzi kumawonjezeka kwambiri ndi kuchuluka kwa ndende. Kukula kumeneku kudzawonekera pa graph ngati phirilo lokwera kwambiri, makamaka m'madera omwe ali ndi chidwi kwambiri.

Zinthu zosonkhezera
Zotsatira za kutentha
Kutentha kumakhudza kwambiri kukhuthala kwa HPMC yankho. Nthawi zambiri, kuwonjezeka kutentha kumachepetsa mamasukidwe akayendedwe a yankho. Izi zili choncho chifukwa kutentha kwakukulu kumayambitsa kusuntha kwa maselo ndikufooketsa mgwirizano pakati pa maunyolo a maselo, motero kuchepetsa kukhuthala.

Zotsatira za kumeta ubweya wa ubweya
Kwa mayankho apamwamba a HPMC, kukhuthala kumakhudzidwanso ndi kumeta ubweya. Pakumeta ubweya wambiri, kuyang'ana kwa maunyolo a molekyulu kumakhala kosasinthasintha ndipo kukangana kwamkati kumachepetsedwa, zomwe zimapangitsa kutsika kowoneka bwino kwa yankho. Chodabwitsa ichi chimatchedwa kumeta ubweya wa ubweya.

Mapulogalamu
Pokonzekera mankhwala, HPMC imagwiritsidwa ntchito kwambiri popaka mapiritsi, mafomu otulutsa nthawi zonse, ndi zokhuthala. Kumvetsetsa momwe ma viscosity amadzimadzi a HPMC amasinthira ndikukhazikika ndikofunikira pakupangira mankhwala oyenera. Mwachitsanzo, mu zokutira piritsi, ndende yoyenera ya HPMC imatha kuwonetsetsa kuti madzi akuya ali ndi mamasukidwe oyenera oti aphimbe pamwamba pa piritsi, pomwe sakhala okwera kwambiri kuti asakhale ovuta kunyamula.

M'makampani azakudya, HPMC imagwiritsidwa ntchito ngati thickener ndi stabilizer. Kumvetsetsa kugwirizana pakati pa ndende ndi mamasukidwe akayendedwe kungathandize kudziwa ndende mulingo woyenera kuonetsetsa kukoma ndi kapangidwe chakudya.

The mamasukidwe akayendedwe a HPMC amadzimadzi njira ali kwambiri zabwino malumikizanidwe ndi ndende. Imawonetsa kuwonjezeka kwa mzere mu gawo la dilute solution komanso kuwonjezereka kwamphamvu kwambiri. Maonekedwe a mamachulukidwe awa ndi ofunikira pakugwiritsa ntchito mafakitale osiyanasiyana, ndipo kumvetsetsa ndikuwongolera kusintha kwamakayendedwe a HPMC ndikofunikira kwambiri pakukhathamiritsa kwazinthu komanso kukonza kwazinthu.